Diabetes Mellitus, Type 1
"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Descriptor ID |
D003922
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| MeSH Number(s) |
C18.452.394.750.124 C19.246.267 C20.111.327
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| Concept/Terms |
Diabetes Mellitus, Type 1- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Insulin-Dependent
- Diabetes Mellitus, Insulin Dependent
- Insulin-Dependent Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent, 1
- Diabetes Mellitus, Juvenile-Onset
- Diabetes Mellitus, Juvenile Onset
- Juvenile-Onset Diabetes Mellitus
- Type 1 Diabetes Mellitus
- Diabetes Mellitus, Sudden-Onset
- Diabetes Mellitus, Sudden Onset
- Mellitus, Sudden-Onset Diabetes
- Sudden-Onset Diabetes Mellitus
- Diabetes Mellitus, Type I
- IDDM
- Insulin-Dependent Diabetes Mellitus 1
- Insulin Dependent Diabetes Mellitus 1
- Juvenile-Onset Diabetes
- Diabetes, Juvenile-Onset
- Juvenile Onset Diabetes
- Diabetes Mellitus, Brittle
- Brittle Diabetes Mellitus
- Diabetes Mellitus, Ketosis-Prone
- Diabetes Mellitus, Ketosis Prone
- Ketosis-Prone Diabetes Mellitus
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Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".
Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".
This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 1 | 3 | | 2016 | 4 | 0 | 4 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 2 | 2 | | 2022 | 4 | 0 | 4 | | 2023 | 3 | 0 | 3 | | 2024 | 3 | 1 | 4 | | 2025 | 3 | 0 | 3 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.
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Greenbaum CJ, Long SA, Gitelman SE, Gaglia JL, Daniels M, Brusko TM, Lord S, Bundy BN, Krischer JP, Haller MJ, Steck AK, DiMeglio LA, Evans-Molina C, Moran A, Prahalad P, Wilson DM, Russell WE, Sherr JL, Raskin P, Clements MA, Moore WV, Libman I, Wassermann K, von Herrath M, Bergholdt R, Hastrup H, Kobernat SE, Kus AM, Tung LW, Goland RS, Herold KC. Phase I Clinical Trial of Islet Antigen-Specific Plasmid Coexpressing Tolerogenic Proteins Demonstrates Safety in Adults With Type 1 Diabetes. Diabetes. 2026 Mar 01; 75(3):506-518.
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Chen KY, Tallon EM, Shyu CR. APEA: A Type 1 Diabetes Self-Management Ambient-AI Assistance Tool that Bridges Trajectory Prediction, Interactive Explanation, and Just-in-Time Adaptive Intervention Action. AMIA Annu Symp Proc. 2024; 2024:257-266.
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Shao X, Le Fur S, Cheung W, Belot MP, Perge K, Bouhours-Nouet N, Bensignor C, Levaillant L, Ge B, Kwan T, Lathrop M, Pastinen T, Bougn?res P. CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci. Sci Rep. 2025 May 08; 15(1):15999.
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Vandervelden C, Lockee B, Barnes M, Tallon EM, Williams DD, Kahkoska A, Cristello Sarteau A, Patton SR, Sonabend RY, Kohlenberg JD, Clements MA. Predicting and Ranking Diabetic Ketoacidosis Risk Among Youth with Type 1 Diabetes with a Clinic-to-Clinic Transferrable Machine Learning Model. Diabetes Technol Ther. 2025 Apr; 27(4):271-282.
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Shapiro MR, Tallon EM, Brown ME, Posgai AL, Clements MA, Brusko TM. Leveraging artificial intelligence and machine learning to accelerate discovery of disease-modifying therapies in type 1 diabetes. Diabetologia. 2025 Mar; 68(3):477-494.
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Patton SR, Bergford S, Gal RL, Calhoun P, Clements MA, Sherr JL, Riddell MC. Fear of hypoglycemia relates to glycemic levels during and after real-world physical activity in adolescents with type 1 diabetes. Diabet Med. 2025 Apr; 42(4):e15482.
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Ohman-Hanson R, Alonso GT, Pyle L, McDonough R, Clements M. Management of diabetic ketoacidosis in children: Does early insulin glargine help improve outcomes? J Diabetes. 2024 Aug; 16(8):e13597.
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Zarse E, Knoll MM, Halpin K, Thompson M, Williams DD, Tallon EM, Kallanagowdar G, Tsai S. Recognizing Complications in Youth With Diabetes Admitted With Diabetic Ketoacidosis Versus Hyperglycemic Hyperosmolar State. J Pediatr Health Care. 2024 Sep-Oct; 38(5):761-768.
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Levy CJ, Bailey R, Laffel LM, Forlenza G, DiMeglio LA, Hughes MS, Brown SA, Aleppo G, Bhargava A, Shah VN, Clements MA, Kipnes M, Bruggeman B, Daniels M, Rodriguez H, Calhoun P, Lum JW, Sasson-Katchalski R, Pinsker JE, Pollom R, Beck RW. Multicenter Evaluation of Ultra-Rapid Lispro Insulin with Control-IQ Technology in Adults, Adolescents, and Children with Type 1 Diabetes. Diabetes Technol Ther. 2024 Sep; 26(9):652-660.
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Bergford S, Riddell MC, Gal RL, Patton SR, Clements MA, Sherr JL, Calhoun P. Predicting Hypoglycemia and Hyperglycemia Risk During and After Activity for Adolescents with Type 1 Diabetes. Diabetes Technol Ther. 2024 Oct; 26(10):728-738.
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