Crohn Disease
"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Descriptor ID |
D003424
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MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
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Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
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Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 2004 | 2 | 1 | 3 | 2007 | 1 | 0 | 1 | 2011 | 3 | 0 | 3 | 2012 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 | 2016 | 1 | 0 | 1 | 2020 | 1 | 1 | 2 | 2021 | 1 | 0 | 1 | 2022 | 2 | 0 | 2 | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Keever-Keigher MR, Harvey L, Williams V, Vyhlidal CA, Ahmed AA, Johnston JJ, Louiselle DA, Grundberg E, Pastinen T, Friesen CA, Chevalier R, Smail C, Shakhnovich V. Genomic insights into pediatric intestinal inflammatory and eosinophilic disorders using single-cell RNA-sequencing. Front Immunol. 2024; 15:1420208.
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Moore MM, Gee MS, Iyer RS, Chan SS, Ayers TD, Bardo DME, Chandra T, Cooper ML, Dotson JL, Gadepalli SK, Gill AE, Levin TL, Nadel HR, Schooler GR, Shet NS, Squires JH, Trout AT, Wall JJ, Rigsby CK. ACR Appropriateness Criteria? Crohn Disease-Child. J Am Coll Radiol. 2022 05; 19(5S):S19-S36.
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Forss A, Clements M, Myrelid P, Strid H, S?derman C, Wagner A, Andersson D, Hjelm F, Ol?n O, Halfvarson J, Ludvigsson JF. Ustekinumab Is Associated with Real-World Long-Term Effectiveness and Improved Health-Related Quality of Life in Crohn's Disease. Dig Dis Sci. 2023 01; 68(1):65-76.
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Forss A, Clements M, Myrelid P, Strid H, S?derman C, Wagner A, Andersson D, Hjelm F, Ol?n O, Ludvigsson JF, Halfvarson J. Prospective observational study on Stelara (ustekinumab) assessing effectiveness in Crohn's disease (PROSE): a 16-week follow-up. Scand J Gastroenterol. 2021 Jun; 56(6):680-686.
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Vyhlidal CA, Chapron BD, Ahmed A, Singh V, Casini R, Shakhnovich V. Effect of Crohn's Disease on Villous Length and CYP3A4 Expression in the Pediatric Small Intestine. Clin Transl Sci. 2021 03; 14(2):729-736.
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Goddard GR, Lim IIP, Cheng YC, Velazco CS, Jenkins T, Rosen NG, Kotagal M, Garrison AP, Falcone R, Rymeski B, Frischer JS. A child presents with perianal symptoms - how often is this Crohn's disease? J Pediatr Surg. 2021 Sep; 56(9):1618-1622.
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Singh M, Singh V, Schurman JV, Friesen CA. Mucosal Th17 Cells Are Increased in Pediatric Functional Dyspepsia Associated with Chronic Gastritis. Dig Dis Sci. 2020 11; 65(11):3184-3190.
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Proksell SS, Greer JB, Theisen BK, Davis PL, Rosh JR, Keljo DJ, Goyal A, Shah SA, Brand MH, Herfarth HH, Cross RK, Siegel CA, Koltun WA, Isaacs KL, Regueiro MD. IBD LIVE Case Series: Case 9: Do Race and Extraintestinal Manifestations Affect Treatment of Severe Crohn's Colitis? Inflamm Bowel Dis. 2018 03 19; 24(4):698-713.
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Shakhnovich V, Vyhlidal C, Friesen C, Hildreth A, Singh V, Daniel J, Kearns GL, Leeder JS. Decreased Pregnane X Receptor Expression in Children with Active Crohn's Disease. Drug Metab Dispos. 2016 07; 44(7):1066-9.
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Goyal A, Hyams JS, Lerer T, Leleiko NS, Otley AR, Griffiths AM, Rosh JR, Cabrera JM, Oliva-Hemker MM, Mack DR, Rick JN, Pfefferkorn MD, Carvalho R, Grossman AB, Hitch MC, Sudel B, Kappelman MD, Saeed SA, Faubion WA, Schaefer ME, Markowitz JF, Keljo DJ. Liver enzyme elevations within 3 months of diagnosis of inflammatory bowel disease and likelihood of liver disease. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):321-3.
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