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Shannon L. Carpenter, MD, MSCI, FAAP

TitleChief, Section of Hematology
InstitutionChildren's Mercy Kansas City
DepartmentPediatrics
Address2401 Gillham Rd
Kansas City MO 64108
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    Other Positions
    TitleAssociate Director, Hematology/Oncology/BMT Division
    InstitutionChildren's Mercy Kansas City
    DepartmentPediatrics

    TitleProfessor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    Virginia Commonwealth University, Richmond, VAMD1998
    Children's Hospital Medical Center, Cincinnati, OHResidency2001Pediatrics
    Duke University, Durham, NCFellowship2004Pediatric Hematology/Oncology
    University of Texas Health Science Center, San Antonio, TXMS2006Clinical Investigation

    Collapse Overview 

    Collapse Research 
    Collapse research overview
    Dr. Carpenter's research focuses on bleeding and clotting disorders. She has published multiple collaborative manuscripts regarding the risk for and prevention of venous thromboembolism in hospitalized pediatric patients. She is currently leading a national trial investigating the development of inhibitors in untreated children with hemophilia. Additionally, she is involved in studies of bleeding disorders in women and girls and rare bleeding disorders. Dr. Carpenter also collaborates with Child Abuse Pediatricians regarding the work-up for bleeding disorders in children suspected of being abused.

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Chrisentery-Singleton T, Boggio LN, Carcao MD, Ibrahimi S, Khan O, Mahajerin A, Rajasekhar A, Sharma V, Steele M, Torres M, Rodino FJ, Carpenter SL. Long-term follow-up of patients with congenital thrombotic thrombocytopenia purpura receiving a plasma-derived factor VIII (Koate) that contains ADAMTS13. Haemophilia. 2023 Nov; 29(6):1638-1645. PMID: 37855744.
      View in: PubMed
    2. Wheeler AP, Lim MY, Huguelet PS, Jaffray J, Staber JM, Funkhouser K, Carpenter SL, Weyand AC. Trends in dedicated care for females with bleeding disorders within U.S. hemophilia treatment centers. Am J Hematol. 2023 Dec; 98(12):E399-E402. PMID: 37800397.
      View in: PubMed
    3. Carpenter SL. More than a baby step toward improved treatment: Commentary on "NEOnatal Central-venous Line Observational study on Thrombosis (NEOCLOT): evaluation of a national guideline on management of neonatal catheter-related venous thrombosis". J Thromb Haemost. 2023 04; 21(4):771-772. PMID: 36990518.
      View in: PubMed
    4. Ragni MV, Young G, Batsuli G, Bisson E, Carpenter SL, Croteau SE, Cuker A, Curtis RG, Denne M, Ewenstein B, Federizo A, Frick N, Funkhouser K, George LA, Hoots WK, Jobe SM, Krava E, Langmead CJ, Lewis RJ, L?pez J, Malec L, Mann Z, Miles ME, Neely E, Neufeld EJ, Pierce GF, Pipe SW, Pitler LR, Raffini L, Schnur KM, Shavit JA. Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: facilitating research through infrastructure, workforce, resources and funding. Expert Rev Hematol. 2023 03; 16(sup1):107-127. PMID: 36920855.
      View in: PubMed
    5. Roberts JC, Kulkarni R, Kouides PA, Sidonio RF, Carpenter SL, Konkle BA, Wu J, Ullman MM, Curtis R, Baker JR, Crook N, Nichol MB. Depression and anxiety in persons with Von Willebrand disease. Haemophilia. 2023 Mar; 29(2):545-554. PMID: 36516311.
      View in: PubMed
    6. Anderst J, Carpenter SL, Abshire TC, Killough E, Mendonca EA, Downs SM, Wetmore C, Allen C, Dickens D, Harper J, Rogers ZR, Jain J, Warwick A, Yates A, Hord J, Lipton J, Wilson H, Kirkwood S, Haney SB, Asnes AG, Gavril AR, Girardet RG, Heavilin N, Gilmartin ABH, Laskey A, Messner SA, Mohr BA, Nienow SM, Rosado N, Idzerda SM, Legano LA, Raj A, Sirotnak AP, Forkey HC, Keeshin B, Matjasko J, Edward H, Chavdar M, Di Paola J, Leavey P, Graham D, Hastings C, Hijiya N, Hord J, Matthews D, Pace B, Velez MC, Wechsler D, Billett A, Stork L, Hooker R. Evaluation for Bleeding Disorders in Suspected Child Abuse. Pediatrics. 2022 10 01; 150(4). PMID: 36180615.
      View in: PubMed
    7. Carpenter SL, Abshire TC, Killough E, Anderst JD. Evaluating for Suspected Child Abuse: Conditions That Predispose to Bleeding. Pediatrics. 2022 10 01; 150(4). PMID: 36120799.
      View in: PubMed
    8. Woods GM, Raffini L, Brand?o LR, Jaffray J, Branchford BR, Ng CJ, Sartain SE, Pak J, Male C, Zia A, Rizzi M, Sirachainan N, Faustino EVS, Carpenter SL, Goldenberg NA. Practical considerations and consensus opinion for children's hospital-based inpatient hemostasis and thrombosis (HAT) consultative services: Communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis. J Thromb Haemost. 2022 09; 20(9):2151-2158. PMID: 35748322.
      View in: PubMed
    9. Escobar M, Dunn A, Quon D, Trzaskoma B, Lee L, Ko RH, Carpenter SL. A phase IV, multicentre, open-label study of emicizumab prophylaxis in people with haemophilia A with or without FVIII inhibitors undergoing minor surgical procedures. Haemophilia. 2022 07; 28(4):e105-e108. PMID: 35510949.
      View in: PubMed
    10. Konkle BA, Quon DV, Raffini L, Recht M, Radulescu VC, Carpenter SL, Dunn AL, Lu M, Watt M. A Prospective Observational Study of Antihemophilic Factor (Recombinant) Prophylaxis Related to Physical Activity Levels in Patients with Hemophilia A in the United States (SPACE). J Blood Med. 2021; 12:883-896. PMID: 34703348.
      View in: PubMed
    11. Thau A, Saffren B, Anderst JD, Carpenter SL, Levin AV. A review on clotting disorders and retinal hemorrhages: Can they mimic abuse? Child Abuse Negl. 2021 08; 118:105070. PMID: 34049052.
      View in: PubMed
    12. Anderst J, Carpenter S, Frazier T, Appavu B, Noetzel M, Beslow LA, Sharma M. Subdural hemorrhage in a cohort with cerebral sinovenous thrombosis: Application to abusive head trauma. Child Abuse Negl. 2021 07; 117:105119. PMID: 34023741.
      View in: PubMed
    13. Thau A, Saffren B, Zakrzewski H, Anderst JD, Carpenter SL, Levin A. Retinal hemorrhage and bleeding disorders in children: A review. Child Abuse Negl. 2021 02; 112:104901. PMID: 33401159.
      View in: PubMed
    14. Abdel-Rahman SM, Gill H, Carpenter SL, Gueye P, Wicklund B, Breitkreutz M, Ghosh A, Kollu A. Design and Usability of an Electronic Health Record-Integrated, Point-of-Care, Clinical Decision Support Tool for Modeling and Simulation of Antihemophilic Factors. Appl Clin Inform. 2020 03; 11(2):253-264. PMID: 32268389.
      View in: PubMed
    15. Carpenter SL. Factoring Them In: Shining the Spotlight on Women and Girls with Congenital Bleeding Disorders. J Womens Health (Larchmt). 2020 05; 29(5):608. PMID: 31916907.
      View in: PubMed
    16. Olaiya O, Amos LE, Carpenter SL. Novel treatment of combined factor V and factor VIII deficiency with Factor Eight Inhibitor Bypass Activity. Haemophilia. 2020 Jan; 26(1):e21-e22. PMID: 31778262.
      View in: PubMed
    17. Amos LE, Yoo B, Miller N, Farrow EG, Walter A, Gibson M, Durham S, Herd S, Soden S, Carpenter SL. Using dried blood spots for variant analysis for patients with haemophilia. Haemophilia. 2019 Sep; 25(5):e339-e341. PMID: 31361374.
      View in: PubMed
    18. Aledort L, Carpenter SL, Cuker A, Kulkarni R, Recht M, Young G, Leissinger C. Why plasma-derived factor VIII? Haemophilia. 2019 May; 25(3):e183-e185. PMID: 30866124.
      View in: PubMed
    19. Amos LE, Silvey M, Hall M, Witmer CM, Carpenter SL. Primary thromboprophylaxis in hospitalized children: A multi-center retrospective analysis. Thromb Res. 2019 Apr; 176:1-7. PMID: 30743065.
      View in: PubMed
    20. Carpenter SL, Goldman J, Sherman AK, Selewski DT, Kallash M, Tran CL, Seamon M, Katsoufis C, Ashoor I, Hernandez J, Supe-Markovina K, D'alessandri-Silva C, DeJesus-Gonzalez N, Vasylyeva TL, Formeck C, Woll C, Gbadegesin R, Geier P, Devarajan P, Smoyer WE, Kerlin BA, Rheault MN. Association of infections and venous thromboembolism in hospitalized children with nephrotic syndrome. Pediatr Nephrol. 2019 02; 34(2):261-267. PMID: 30194664.
      View in: PubMed
    21. McWilliams A, Roberge J, Anderson WE, Moore CG, Rossman W, Murphy S, McCall S, Brown R, Carpenter S, Rissmiller S, Furney S. Aiming to Improve Readmissions Through InteGrated Hospital Transitions (AIRTIGHT): a Pragmatic Randomized Controlled Trial. J Gen Intern Med. 2019 01; 34(1):58-64. PMID: 30109585.
      View in: PubMed
    22. Carpenter SL, Richardson T, Hall M. Increasing rate of pulmonary embolism diagnosed in hospitalized children in the United States from 2001 to 2014. Blood Adv. 2018 06 26; 2(12):1403-1408. PMID: 29907635.
      View in: PubMed
    23. Carpenter SL, Khair K, Gringeri A, Valentino LA. Prophylactic bypassing agent use before and during immune tolerance induction in patients with haemophilia A and inhibitors to FVIII. Haemophilia. 2018 Jul; 24(4):570-577. PMID: 29901839.
      View in: PubMed
    24. Branchford BR, Carpenter SL. The Role of Inflammation in Venous Thromboembolism. Front Pediatr. 2018; 6:142. PMID: 29876337.
      View in: PubMed
    25. Anderst JD, Carpenter SL, Presley R, Berkoff MC, Wheeler AP, Sidonio RF, Soucie JM. Relevance of Abusive Head Trauma to Intracranial Hemorrhages and Bleeding Disorders. Pediatrics. 2018 05; 141(5). PMID: 29695583.
      View in: PubMed
    26. Silvey M, Hall M, Bilynsky E, Carpenter SL. Increasing rates of thrombosis in children with congenital heart disease undergoing cardiac surgery. Thromb Res. 2018 02; 162:15-21. PMID: 29253719.
      View in: PubMed
    27. Michael Wiater J, Carpenter S, Koueiter DM, Marcantonio D, Wiater BP. Influence of Body Mass Index on Clinical Outcomes in Reverse Total Shoulder Arthroplasty. J Surg Orthop Adv. 2017 FALL; 26(3):134-142. PMID: 29130873.
      View in: PubMed
    28. McGuinn C, Cheng D, Aschman D, Carpenter SL, Sidonio R, Soni A, Tarantino MD, Wheeler AP, Dunn AL. Radionuclide synovectomy/synoviorthesis (RS) in patients with bleeding disorders: A review of patient and procedure demographics and functional outcomes in the ATHNdataset. Haemophilia. 2017 Nov; 23(6):926-933. PMID: 28838029.
      View in: PubMed
    29. Sharma R, Dunn A, Aschman D, Cheng D, Wheeler A, Soni A, McGuinn C, Knoll C, Stein DT, Young G, French J, Sanders J, Davis JA, Tarantino M, Lim M, Gruppo R, Sidonio R, Ahuja S, Carpenter S, Pipe S, Shapiro A. Radionuclide synovectomy/synoviorthesis (RS) in persons with bleeding disorders: A review of impact of national guidance on frequency of RS using the ATHNdataset. Haemophilia. 2017 07; 23(4):e385-e388. PMID: 28544271.
      View in: PubMed
    30. Reeves JA, Dowlut-McElroy T, Mou SM, Strickland JL, Carpenter SL. Factor VII deficiency diagnosed after minor genital trauma. Haemophilia. 2017 03; 23(2):e133-e135. PMID: 28111834.
      View in: PubMed
    31. Amos LE, Carpenter SL, Hoeltzel MF. Lost at Sea in Search of a Diagnosis: A Case of Unexplained Bleeding. Pediatr Blood Cancer. 2016 07; 63(7):1305-6. PMID: 27062477.
      View in: PubMed
    32. Carpenter SL, Goldman J, Sherman AK, Jeremiah Bell J, Selveraju S, Newland JG, Jarka DE, Chastain K, Selvarangan R. Clinical variables and Staphylococcus aureus virulence factors associated with venous thromboembolism in children. Thromb Res. 2016 Feb; 138:69-73. PMID: 26709039.
      View in: PubMed
    33. Iverson KM, Vogt D, Dichter ME, Carpenter SL, Kimerling R, Street AE, Gerber MR. Intimate Partner Violence and Current Mental Health Needs Among Female Veterans. J Am Board Fam Med. 2015 Nov-Dec; 28(6):772-6. PMID: 26546653.
      View in: PubMed
    34. Rheault MN, Zhang L, Selewski DT, Kallash M, Tran CL, Seamon M, Katsoufis C, Ashoor I, Hernandez J, Supe-Markovina K, D'Alessandri-Silva C, DeJesus-Gonzalez N, Vasylyeva TL, Formeck C, Woll C, Gbadegesin R, Geier P, Devarajan P, Carpenter SL, Kerlin BA, Smoyer WE. AKI in Children Hospitalized with Nephrotic Syndrome. Clin J Am Soc Nephrol. 2015 Dec 07; 10(12):2110-8. PMID: 26450933.
      View in: PubMed
    35. Willig LK, Petrikin JE, Smith LD, Saunders CJ, Thiffault I, Miller NA, Soden SE, Cakici JA, Herd SM, Twist G, Noll A, Creed M, Alba PM, Carpenter SL, Clements MA, Fischer RT, Hays JA, Kilbride H, McDonough RJ, Rosterman JL, Tsai SL, Zellmer L, Farrow EG, Kingsmore SF. Whole-genome sequencing for identification of Mendelian disorders in critically ill infants: a retrospective analysis of diagnostic and clinical findings. Lancet Respir Med. 2015 May; 3(5):377-87. PMID: 25937001.
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    36. Dowlut-McElroy T, Williams KB, Carpenter SL, Strickland JL. Menstrual Patterns and Treatment of Heavy Menstrual Bleeding in Adolescents with Bleeding Disorders. J Pediatr Adolesc Gynecol. 2015 Dec; 28(6):499-501. PMID: 26231609.
      View in: PubMed
    37. Silvey MS, Carpenter SL, Wicklund BM. The development of pulmonary embolus in patients with haemophilia A and high-titre inhibitors - a case series and review of the literature. Haemophilia. 2015 Mar; 21(2):e134-e136. PMID: 25643736.
      View in: PubMed
    38. Antun A, Monahan PE, Manco-Johnson MJ, Callaghan MU, Kanin M, Knoll C, Carpenter SL, Davis JA, Guerrera MF, Kruse-Jarres R, Ragni MV, Witmer C, McCracken CE, Kempton CL. Inhibitor recurrence following immune tolerance induction: A multicenter retrospective cohort study. J Thromb Haemost. 2015; DOI: 10.1111/jth.13143.
    39. Jackson J, Miller M, Moffatt M, Carpenter S, Sherman A, Anderst J. Bruising in Children: Practice Patterns of Pediatric Hematologists and Child Abuse Pediatricians. Clin Pediatr (Phila). 2015 Jun; 54(6):563-9. PMID: 25398626.
      View in: PubMed
    40. Carpenter SL, Soucie JM, Presley RJ, Ragni MV, Wicklund BM, Silvey M, Davidson H. Hepatitis B vaccination is effective by subcutaneous route in children with bleeding disorders: a universal data collection database analysis. Haemophilia. 2015 Jan; 21(1):e39-43. PMID: 25381731.
      View in: PubMed
    41. Paroskie A, Carpenter SL, Lowen DE, Anderst J, DeBaun MR, Sidonio RF. A two-center retrospective review of the hematologic evaluation and laboratory abnormalities in suspected victims of non-accidental injury. Child Abuse Negl. 2014 Nov; 38(11):1794-800. PMID: 24928052.
      View in: PubMed
    42. Thornton KM, Nyp MF, Music Aplenc L, Jones GL, Carpenter SL, Guest EM, Shapiro SM, Manimtim WM. An unusual case of rapidly progressive hyperbilirubinemia. Case Rep Pediatr. 2013; 2013:284029. PMID: 24288641.
      View in: PubMed
    43. Anderst J, Carpenter S. A single case report lacking details does not equal a mimic of abusive head trauma. J Forensic Leg Med. 2013 Nov; 20(8):1149-50. PMID: 24237842.
      View in: PubMed
    44. Carpenter SL. Fighting the hydra: current understanding of pediatric thrombosis. Curr Probl Pediatr Adolesc Health Care. 2013 Aug; 43(7):162. PMID: 23890022.
      View in: PubMed
    45. Silvey M, Carpenter SL. Inherited thrombophilia in children. Curr Probl Pediatr Adolesc Health Care. 2013 Aug; 43(7):163-8. PMID: 23890023.
      View in: PubMed
    46. Tolbert J, Carpenter SL. Common acquired causes of thrombosis in children. Curr Probl Pediatr Adolesc Health Care. 2013 Aug; 43(7):169-77. PMID: 23890024.
      View in: PubMed
    47. Sharma M, Carpenter SL. Thromboprophylaxis in a pediatric hospital. Curr Probl Pediatr Adolesc Health Care. 2013 Aug; 43(7):178-83. PMID: 23890025.
      View in: PubMed
    48. Carpenter SL, Abshire TC, Anderst JD. Evaluating for suspected child abuse: conditions that predispose to bleeding. Pediatrics. 2013 Apr; 131(4):e1357-73. PMID: 23530171.
      View in: PubMed
    49. Anderst JD, Carpenter SL, Abshire TC. Evaluation for bleeding disorders in suspected child abuse. Pediatrics. 2013 Apr; 131(4):e1314-22. PMID: 23530182.
      View in: PubMed
    50. Narang SK., Melville JD, Greeley CS, Anderst JD, Carpenter SL, Spivack B. A Daubert Analysis of Abusive Head Trauma/Shaken Baby Syndrome—Part II: An Examination of the Differential Diagnosis. Hous J. Health L.& Policy. 2013; 203.
    51. Gringeri A, Leissinger C, Cortesi PA, Jo H, Fusco F, Riva S, Antmen B, Berntorp E, Biasoli C, Carpenter S, Kavkli K, Morfini M, Negrier C, Rocino A, Schramm W, Uscatescu MV, Windyga J, Zulfikar B, Montavani LG. Health-related quality of life in patients with haemophilia and inhibitors on prophylaxis with anti-inhibitor complex concentrate: results from the Pro-FEIBA study. Haemophilia. 2013; doi: 10.1111/hae.12178. [Epub .
    52. Radhi M, Carpenter SL. Thrombotic microangiopathies. ISRN Hematol. 2012; 2012:310596. PMID: 22888446.
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    53. Jackson J, Carpenter S, Anderst J. Challenges in the evaluation for possible abuse: presentations of congenital bleeding disorders in childhood. Child Abuse Negl. 2012 Feb; 36(2):127-34. PMID: 22398301.
      View in: PubMed
    54. Thornburg CD, Carpenter S, Zappa S, Munn J, Leissinger C. Current prescription of prophylactic factor infusions and perceived adherence for children and adolescents with haemophilia: a survey of haemophilia healthcare professionals in the United States. Haemophilia. 2012 Jul; 18(4):568-74. PMID: 22335526.
      View in: PubMed
    55. Carpenter SL, Michael Soucie J, Sterner S, Presley R. Increased prevalence of inhibitors in Hispanic patients with severe haemophilia A enrolled in the Universal Data Collection database. Haemophilia. 2012 May; 18(3):e260-5. PMID: 22250850.
      View in: PubMed
    56. Leissinger C, Gringeri A, Antmen B, Berntorp E, Biasoli C, Carpenter S, Cortesi P, Jo H, Kavakli K, Lassila R, Morfini M, N?grier C, Rocino A, Schramm W, Serban M, Uscatescu MV, Windyga J, Z?lfikar B, Mantovani L. Anti-inhibitor coagulant complex prophylaxis in hemophilia with inhibitors. N Engl J Med. 2011 Nov 03; 365(18):1684-92. PMID: 22047559.
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    57. Adame N, Carpenter SL. Closing the loophole: midwives and the administration of vitamin K in neonates. J Pediatr. 2009 May; 154(5):769-71. PMID: 19364563.
      View in: PubMed
    58. Carpenter SL, Lieff S, Howard TA, Eggleston B, Ware RE. UGT1A1 promoter polymorphisms and the development of hyperbilirubinemia and gallbladder disease in children with sickle cell anemia. Am J Hematol. 2008 Oct; 83(10):800-3. PMID: 18756540.
      View in: PubMed
    59. Carpenter SL, Mathew P. a2- Antiplasmin and its deficiency: Fibrinolysis out of balance. Haemophilia. 2008; 14(6):1250-1254.
    60. Carpenter SL, Zimmerman SA, Ware RE. Acute parvovirus B19 infection mimicking congenital dyserythropoietic anemia. J Pediatr Hematol Oncol. 2004 Feb; 26(2):133-5. PMID: 14767207.
      View in: PubMed
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