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"Alarmins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A structurally diverse group of endogenous molecules that includes the HMGB1 PROTEIN; S100 PROTEINS; HSP60, Hsp70, Cathelicidin, IL-33, and DEFENSINS. They are constitutively available, released upon tissue damage, and activate the immune system. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.

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