 Mice, Inbred CFTR
"Mice, Inbred CFTR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
| Descriptor ID |
D018181
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| MeSH Number(s) |
B01.050.050.199.520.520.445 B01.050.150.900.649.865.635.505.500.400.445
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| Concept/Terms |
Mice, Inbred CFTR- Mice, Inbred CFTR
- CFTR Mice, Inbred
- Inbred CFTR Mice
- Mouse, CFTR
- CFTR Mouse
- Mouse, Inbred CFTR
- CFTR Mouse, Inbred
- Inbred CFTR Mouse
- Mice, CFTR
- CFTR Mice
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