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Fridley, Brooke

One or more keywords matched the following items that are connected to Fridley, Brooke

Item Type	Name
Concept	Cell Line, Tumor
Academic Article	Bayseian genomic models for the incorporation of pathway topology knowledge into association studies.
Academic Article	Integrative gene set analysis: application to platinum pharmacogenomics.
Academic Article	Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.
Academic Article	Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.
Academic Article	Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Academic Article	Genome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.
Academic Article	Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.
Academic Article	HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Academic Article	HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.
Academic Article	Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer.
Academic Article	Drug discovery using clinical outcome-based Connectivity Mapping: application to ovarian cancer.
Academic Article	Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines.
Academic Article	Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.
Academic Article	Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines.
Academic Article	Nonlinear mixed-effects models for modeling in vitro drug response data to determine problematic cancer cell lines.
Academic Article	Modeling phenotypic heterogeneity towards evolutionarily inspired osteosarcoma therapy.
Academic Article	Gemcitabine and cytosine arabinoside cytotoxicity: association with lymphoblastoid cell expression.
Academic Article	FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.
Academic Article	Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen.
Academic Article	LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.
Academic Article	Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
Academic Article	Gene set analysis of purine and pyrimidine antimetabolites cancer therapies.
Academic Article	A Bayesian integrative genomic model for pathway analysis of complex traits.
Academic Article	Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.

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Cell Line Tumor