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Search Results to Tomoo Iwakuma

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research overview Dr. Iwakuma's primary research focuses on the field of Cancer Research, especially dissecting the mechanism of cancer progression and discovering novel drugs or compounds that specifically kill cancer cells, with special focus on the tumor suppressor p53 pathway.

One or more keywords matched the following items that are connected to Iwakuma, Tomoo

Item TypeName
Concept B-Lymphocytes
Concept Cells, Cultured
Concept HeLa Cells
Concept Stem Cells
Concept Tumor Cells, Cultured
Concept Neoplastic Stem Cells
Concept CD4-Positive T-Lymphocytes
Concept Th1 Cells
Concept Enteroendocrine Cells
Concept NIH 3T3 Cells
Concept HCT116 Cells
Concept Th17 Cells
Grant The role of MDM2-MTBP axis in cancer metastasis
Academic Article Metastatic potential of tumor-initiating cells in solid tumors.
Academic Article Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis.
Academic Article Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities.
Academic Article Genome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer.
Academic Article Unsaturated fatty acids regulate stemness of ovarian cancer cells through NF-?B.
Academic Article Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma.
Academic Article Regulation of cytotoxic T-cell responses by p53 in cancer.
Academic Article EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells.
Academic Article Self-inactivating lentiviral vectors with U3 and U5 modifications.
Academic Article Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system.
Academic Article Suppressing STAT5 signaling affects osteosarcoma growth and stemness.
Academic Article Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
Academic Article Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.
Academic Article Mdm2 and Mdm4 loss regulates distinct p53 activities.
Academic Article Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway.
Academic Article A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.
Academic Article CD117 and Stro-1 identify osteosarcoma tumor-initiating cells associated with metastasis and drug resistance.
Academic Article Colonic L-cell impairment in aged subjects with type 2 diabetes leads to diminished GLP-1 production.
Academic Article Genes to Cells

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