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Iwakuma, Tomoo

One or more keywords matched the following items that are connected to Iwakuma, Tomoo

Item Type	Name
Concept	Mutation
Concept	Point Mutation
Concept	Mutation, Missense
Academic Article	Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing.
Academic Article	Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities.
Academic Article	DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway.
Academic Article	Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma.
Academic Article	Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase.
Academic Article	The interplay between mutant p53 and the mevalonate pathway.
Academic Article	Emerging Non-Canonical Functions and Regulation of p53.
Academic Article	[Study on carcinogenesis and mutation suppression: repair of alkylation DNA damage and suppression of tumors].
Academic Article	TP53 in bone and soft tissue sarcomas.
Academic Article	Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
Academic Article	Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
Academic Article	Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.
Academic Article	Li-Fraumeni syndrome: a p53 family affair.
Academic Article	Crippling p53 activities via knock-in mutations in mouse models.
Academic Article	Mutant p53 gain of oncogenic function: in vivo evidence, mechanism of action and its clinical implications.
Academic Article	Drugs Targeting p53 Mutations with FDA Approval and in Clinical Trials.
Academic Article	Therapeutic potential of combating cancer by restoring wild-type p53 through mRNA nanodelivery.

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Mutation