Item Type | Name |
Concept
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Blood Proteins
|
Concept
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Calmodulin-Binding Proteins
|
Concept
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Chromosomal Proteins, Non-Histone
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Concept
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Cytoskeletal Proteins
|
Concept
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DNA-Binding Proteins
|
Concept
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Eye Proteins
|
Concept
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Fungal Proteins
|
Concept
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Intermediate Filament Proteins
|
Concept
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Luminescent Proteins
|
Concept
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Membrane Proteins
|
Concept
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Microtubule-Associated Proteins
|
Concept
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Muscle Proteins
|
Concept
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Neoplasm Proteins
|
Concept
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Nerve Tissue Proteins
|
Concept
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Nuclear Proteins
|
Concept
|
Oncogene Proteins, Viral
|
Concept
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Proteins
|
Concept
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Proto-Oncogene Proteins
|
Concept
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Recombinant Fusion Proteins
|
Concept
|
Recombinant Proteins
|
Concept
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Repressor Proteins
|
Concept
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Retroviridae Proteins
|
Concept
|
Viral Proteins
|
Concept
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Oncogene Proteins
|
Concept
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Proto-Oncogene Proteins c-myc
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Concept
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Proto-Oncogene Proteins p21(ras)
|
Concept
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Extracellular Matrix Proteins
|
Concept
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Proto-Oncogene Proteins c-jun
|
Concept
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Proto-Oncogene Proteins c-fos
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Concept
|
Oncogene Proteins v-fos
|
Concept
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Immediate-Early Proteins
|
Concept
|
Homeodomain Proteins
|
Concept
|
Cell Cycle Proteins
|
Concept
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Proto-Oncogene Proteins c-bcl-2
|
Concept
|
GTPase-Activating Proteins
|
Concept
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CCAAT-Enhancer-Binding Proteins
|
Concept
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Tumor Suppressor Proteins
|
Concept
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LDL-Receptor Related Proteins
|
Concept
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Saccharomyces cerevisiae Proteins
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Concept
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Escherichia coli Proteins
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Concept
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Adaptor Proteins, Vesicular Transport
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Concept
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Intracellular Signaling Peptides and Proteins
|
Concept
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Adaptor Proteins, Signal Transducing
|
Concept
|
Green Fluorescent Proteins
|
Concept
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Proto-Oncogene Proteins c-crk
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Concept
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Apoptosis Regulatory Proteins
|
Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proto-Oncogene Proteins c-maf
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Concept
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Hedgehog Proteins
|
Concept
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GPI-Linked Proteins
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Academic Article
|
Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL).
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Academic Article
|
Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer.
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Academic Article
|
Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.
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Academic Article
|
Crk proteins transduce FGF signaling to promote lens fiber cell elongation.
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Academic Article
|
Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
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Academic Article
|
Nestin Mediates Hedgehog Pathway Tumorigenesis.
|
Academic Article
|
CRK proteins selectively regulate T cell migration into inflamed tissues.
|
Academic Article
|
Crk and CrkL are required for cell transformation by v-fos and v-ras.
|
Academic Article
|
Neurobiology: Reelin mediates form and function.
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Academic Article
|
Dendritic planarity of Purkinje cells is independent of Reelin signaling.
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Academic Article
|
Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis.
|
Academic Article
|
Essential roles of Crk and CrkL in fibroblast structure and motility.
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Academic Article
|
Yayoi era mutation disrupts brain and muscle.
|
Academic Article
|
Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse.
|
Academic Article
|
Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.
|
Academic Article
|
A gene expression approach to mapping the functional maturation of the hippocampus.
|
Academic Article
|
Role of DNA 5-methylcytosine transferase in cell transformation by fos.
|
Academic Article
|
Reelin regulates the development and synaptogenesis of the layer-specific entorhino-hippocampal connections.
|
Academic Article
|
Gene dosage in mice--BAC to the future.
|
Academic Article
|
Thyroid hormone regulates reelin and dab1 expression during brain development.
|
Academic Article
|
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.
|
Academic Article
|
Mutant mice with scrambled brains: understanding the signaling pathways that control cell positioning in the CNS.
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Academic Article
|
Reelin is a ligand for lipoprotein receptors.
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Academic Article
|
The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched.
|
Academic Article
|
Cortical development: Cdk5 gets into sticky situations.
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Academic Article
|
Reelin mRNA expression during embryonic brain development in the chick.
|
Academic Article
|
Disabled-1 is expressed in type AII amacrine cells in the mouse retina.
|
Academic Article
|
Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.
|
Academic Article
|
Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1.
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Academic Article
|
Role of the reelin signaling pathway in central nervous system development.
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Academic Article
|
The reelin pathway modulates the structure and function of retinal synaptic circuitry.
|
Academic Article
|
Disabled-1 interacts with a novel developmentally regulated protocadherin.
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Academic Article
|
Brain development: integrins and the Reelin pathway.
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Academic Article
|
Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.
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Academic Article
|
Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling.
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Academic Article
|
ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.
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Academic Article
|
mPPP1R16B is a novel mouse protein phosphatase 1 targeting subunit whose mRNA is located in cell bodies and dendrites of neurons in four distinct regions of the brain.
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Academic Article
|
Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1.
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Academic Article
|
Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding.
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Academic Article
|
Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma.
|
Academic Article
|
Crystal structures of the Dab homology domains of mouse disabled 1 and 2.
|
Academic Article
|
Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain.
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Academic Article
|
Differential binding of ligands to the apolipoprotein E receptor 2.
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Academic Article
|
Components of the reelin signaling pathway are expressed in the spinal cord.
|
Academic Article
|
Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins.
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Academic Article
|
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.
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Academic Article
|
Gli1 is important for medulloblastoma formation in Ptc1+/- mice.
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Academic Article
|
A transcriptome map of cellular transformation by the fos oncogene.
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Academic Article
|
Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics.
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Academic Article
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The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
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Academic Article
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Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies.
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Academic Article
|
The hedgehog pathway and neurological disorders.
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Academic Article
|
Cardiovascular and craniofacial defects in Crk-null mice.
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Academic Article
|
Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor.
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Academic Article
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Loss of suppressor-of-fused function promotes tumorigenesis.
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Academic Article
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Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality.
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Academic Article
|
Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure.
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Academic Article
|
Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling.
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Academic Article
|
Cancer: Hedgehog's other great trick.
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Academic Article
|
Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway.
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Academic Article
|
Ectopic expression of reelin alters migration of sympathetic preganglionic neurons in the spinal cord.
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Academic Article
|
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor.
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Academic Article
|
Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L.
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Academic Article
|
The genetic landscape of the childhood cancer medulloblastoma.
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Academic Article
|
PTHrP treatment fails to rescue bone defects caused by Hedgehog pathway inhibition in young mice.
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Academic Article
|
The Hedgehog's tale: developing strategies for targeting cancer.
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Academic Article
|
The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress.
|
Academic Article
|
Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.
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Academic Article
|
Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity.
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Academic Article
|
Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.
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Academic Article
|
Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
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Academic Article
|
The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice.
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Academic Article
|
Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53.
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Academic Article
|
Whole-exome identifies RXRG and TH germline variants in familial isolated prolactinoma.
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Academic Article
|
Fos and Jun: oncogenic transcription factors.
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Academic Article
|
Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts.
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Academic Article
|
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.
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Academic Article
|
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.
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Academic Article
|
Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling.
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Academic Article
|
Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase.
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Academic Article
|
fos-lacZ transgenic mice: mapping sites of gene induction in the central nervous system.
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Academic Article
|
Fos is phosphorylated by p34cdc2, cAMP-dependent protein kinase and protein kinase C at multiple sites clustered within regulatory regions.
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Academic Article
|
Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.
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Academic Article
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Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun.
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Academic Article
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Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains.
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Academic Article
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Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity.
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Academic Article
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Fosvergnügen. The excitement of immediate-early genes.
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Academic Article
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Inhibition of jun transformation by a mutated fos gene: design of an anti-oncogene.
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Academic Article
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DNA bending by Fos and Jun: the flexible hinge model.
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Academic Article
|
Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.
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Academic Article
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Analysis of dimerization and DNA binding functions in Fos and Jun by domain-swapping: involvement of residues outside the leucine zipper/basic region.
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Academic Article
|
Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements.
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Academic Article
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Induction of c-fos mRNA expression by afterdischarge in the hippocampus of naive and kindled rats.
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Academic Article
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Redox regulation of fos and jun DNA-binding activity in vitro.
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Academic Article
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Fos and jun cooperate in transcriptional regulation via heterologous activation domains.
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Academic Article
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Altered protein conformation on DNA binding by Fos and Jun.
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Academic Article
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Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.
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Academic Article
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A ubiquitous nuclear protein stimulates the DNA-binding activity of fos and jun indirectly.
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Academic Article
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Inducible proto-oncogenes of the nervous system: their contribution to transcription factors and neuroplasticity.
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Academic Article
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Inducible proto-oncogene transcription factors: third messengers in the brain?
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Academic Article
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Encounters with Fos and Jun on the road to AP-1.
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Academic Article
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Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1.
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Academic Article
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Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence.
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Academic Article
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Barium modulates c-fos expression and post-translational modification.
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Academic Article
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Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.
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Academic Article
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Stimulus-transcription coupling in neurons: role of cellular immediate-early genes.
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Academic Article
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The carboxy terminus of the viral Jun oncoprotein is required for complex formation with the cellular Fos protein.
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Academic Article
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Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains.
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Academic Article
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The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.
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Academic Article
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Regulation of proenkephalin by Fos and Jun.
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Academic Article
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Calcium and proto-oncogene involvement in the immediate-early response in the nervous system.
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Academic Article
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Dynamic alterations occur in the levels and composition of transcription factor AP-1 complexes after seizure.
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Academic Article
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The structure and function of the fos proto-oncogene.
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Academic Article
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Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain.
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Academic Article
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The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites.
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Academic Article
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Extended life span and tumorigenicity of nonestablished mouse connective tissue cells transformed by the fos oncogene of FBR-MuSV.
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Academic Article
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Deletion of the gag region from FBR murine osteosarcoma virus does not affect its enhanced transforming activity.
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Academic Article
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The fos gene product undergoes extensive post-translational modification in eukaryotic but not in prokaryotic cells.
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Academic Article
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Mapping patterns of c-fos expression in the central nervous system after seizure.
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Academic Article
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Beyond the second messenger: oncogenes and transcription factors.
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Academic Article
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Microinjection of transforming ras protein induces c-fos expression.
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Academic Article
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Memories of fos.
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Academic Article
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Common DNA binding site for Fos protein complexes and transcription factor AP-1.
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Academic Article
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A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.
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Academic Article
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Fos-associated protein p39 is the product of the jun proto-oncogene.
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Academic Article
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Expression of c-fos protein in brain: metabolic mapping at the cellular level.
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Academic Article
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fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.
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Academic Article
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Fos and Jun: the AP-1 connection.
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Academic Article
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Calcium as a modulator of the immediate-early gene cascade in neurons.
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Academic Article
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Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos protein.
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Academic Article
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Analysis of Fos protein complexes and Fos-related antigens by high-resolution two-dimensional gel electrophoresis.
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Academic Article
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Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.
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Academic Article
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The Fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose.
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Academic Article
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Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein.
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Academic Article
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FBR murine osteosarcoma virus. I. Molecular analysis and characterization of a 75,000-Da gag-fos fusion product.
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Academic Article
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FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences acquired from two cellular genes.
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Academic Article
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Identification of a 39,000-dalton protein in cells transformed by the FBJ murine osteosarcoma virus.
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Academic Article
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Candidate product of the FBJ murine osteosarcoma virus oncogene: characterization of a 55,000-dalton phosphoprotein.
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Academic Article
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Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini.
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Academic Article
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Viral and cellular fos proteins: a comparative analysis.
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Academic Article
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Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.
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Academic Article
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c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene.
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Academic Article
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The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains.
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Academic Article
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Transcription factors as molecular mediators in cell death.
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Academic Article
|
Reeler gene discrepancies.
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Academic Article
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Use of fluorescence resonance energy transfer to estimate intramolecular distances in the Msx-1 homeodomain.
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Academic Article
|
Human genetics. Smart transcription factors.
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Academic Article
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Apoptosis in the nervous system: new revelations.
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Academic Article
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A protein related to extracellular matrix proteins deleted in the mouse mutant reeler.
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Academic Article
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Fos: an immediate-early transcription factor in neurons.
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Academic Article
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Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats.
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Academic Article
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Analysis of c-Fos and c-Jun redox-dependent DNA binding activity.
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Academic Article
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Transcription. Zen and the art of Fos and Jun.
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Academic Article
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Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements.
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Academic Article
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Design of a "minimAl" homeodomain: the N-terminal arm modulates DNA binding affinity and stabilizes homeodomain structure.
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Academic Article
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A central role for Fos in human B- and T-cell NFAT (nuclear factor of activated T cells): an acidic region is required for in vitro assembly.
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Academic Article
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A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins.
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Academic Article
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Energy transfer analysis of Fos-Jun dimerization and DNA binding.
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Academic Article
|
Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.
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Academic Article
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Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun.
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Academic Article
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Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle.
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Academic Article
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Isolation of the cyclosporin-sensitive T cell transcription factor NFATp.
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Academic Article
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Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.
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Academic Article
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Differential roles for Fos and Jun in DNA-binding: redox-dependent and independent functions.
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Academic Article
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Dimerization and DNA binding alter phosphorylation of Fos and Jun.
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Academic Article
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Selective DNA bending by a variety of bZIP proteins.
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Academic Article
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The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun.
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Academic Article
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The regulation of c-fos: too much is never enough.
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Academic Article
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Escape from redox regulation enhances the transforming activity of Fos.
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Academic Article
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Continuous c-fos expression precedes programmed cell death in vivo.
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Academic Article
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Regulation of proto-oncogene expression in adult and developing lungs.
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Academic Article
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Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro.
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Academic Article
|
Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes.
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Academic Article
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Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF.
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Academic Article
|
An enhanced immune response in mice lacking the transcription factor NFAT1.
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Academic Article
|
The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.
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Academic Article
|
Developmental expression of Fos-lacZ in the brains of postnatal transgenic rats.
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Academic Article
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c-Jun stimulates origin-dependent DNA unwinding by polyomavirus large Tantigen.
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Academic Article
|
Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody.
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Academic Article
|
The human reelin gene: isolation, sequencing, and mapping on chromosome 7.
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Academic Article
|
Identification of redox/repair protein Ref-1 as a potent activator of p53.
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Academic Article
|
The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions.
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Academic Article
|
Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice.
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Academic Article
|
Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin.
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Academic Article
|
Reeler: new tales on an old mutant mouse.
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Academic Article
|
Role of reelin in the control of brain development.
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Academic Article
|
Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.
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Academic Article
|
Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
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Academic Article
|
Requirement for Crk and CrkL during postnatal lens development.
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Academic Article
|
Quantitative assessment of glioblastoma phenotypes in vitro establishes cell migration as a robust readout of Crk and CrkL activity.
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Academic Article
|
Statins repress hedgehog signaling in medulloblastoma with no bone toxicities.
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Academic Article
|
Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.
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