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Search Results to Tom Curran

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One or more keywords matched the following items that are connected to Curran, Tom

Item TypeName
Concept Cells, Cultured
Concept Tumor Cells, Cultured
Academic Article Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
Academic Article CRK proteins selectively regulate T cell migration into inflamed tissues.
Academic Article Essential roles of Crk and CrkL in fibroblast structure and motility.
Academic Article Disabled-1 interacts with a novel developmentally regulated protocadherin.
Academic Article ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.
Academic Article Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1.
Academic Article Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma.
Academic Article Differential binding of ligands to the apolipoprotein E receptor 2.
Academic Article Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.
Academic Article Gli1 is important for medulloblastoma formation in Ptc1+/- mice.
Academic Article The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Academic Article Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure.
Academic Article Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling.
Academic Article The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress.
Academic Article Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity.
Academic Article Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling.
Academic Article fos-lacZ transgenic mice: mapping sites of gene induction in the central nervous system.
Academic Article Inhibition of jun transformation by a mutated fos gene: design of an anti-oncogene.
Academic Article Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements.
Academic Article Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.
Academic Article Inducible proto-oncogenes of the nervous system: their contribution to transcription factors and neuroplasticity.
Academic Article Barium modulates c-fos expression and post-translational modification.
Academic Article The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.
Academic Article Extended life span and tumorigenicity of nonestablished mouse connective tissue cells transformed by the fos oncogene of FBR-MuSV.
Academic Article Deletion of the gag region from FBR murine osteosarcoma virus does not affect its enhanced transforming activity.
Academic Article Microinjection of transforming ras protein induces c-fos expression.
Academic Article The effects of phorbol ester and Ca ionophore on c-fos and c-myc expression and on DNA synthesis in human lymphocytes are not directly related.
Academic Article A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.
Academic Article Calcium as a modulator of the immediate-early gene cascade in neurons.
Academic Article Expression of c-fos in NIH3T3 cells is very low but inducible throughout the cell cycle.
Academic Article Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells.
Academic Article A central role for Fos in human B- and T-cell NFAT (nuclear factor of activated T cells): an acidic region is required for in vitro assembly.
Academic Article Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death.
Academic Article Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.
Academic Article Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle.
Academic Article Continuous c-fos expression precedes programmed cell death in vivo.
Academic Article Functional NMDA receptors are transiently active and support the survival of Purkinje cells in culture.

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