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Search Results to Andrea Gaedigk

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One or more keywords matched the following items that are connected to Gaedigk, Andrea

Item TypeName
Concept Dextromethorphan
Academic Article Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.
Academic Article Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine.
Academic Article Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans.
Academic Article CYP2D6 inhibition by selective serotonin reuptake inhibitors: analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6.
Academic Article Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".
Academic Article Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans.
Academic Article Identification of CYP2D6 impaired functional alleles in Mexican Americans.
Academic Article Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail.
Academic Article CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.
Academic Article Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.
Academic Article Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype.
Academic Article The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
Academic Article Evaluation of a [13C]-dextromethorphan breath test to assess CYP2D6 phenotype.
Academic Article Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual.
Academic Article Six-month, prospective, longitudinal, open-label caffeine and dextromethorphan phenotyping study in children with growth hormone deficiency receiving recombinant human growth hormone replacement.
Academic Article Variability in drug metabolizing enzyme activity in HIV-infected patients.
Academic Article Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations.
Academic Article Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan.
Academic Article Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics.
Academic Article In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report.
Academic Article Pharmacogenetic comparison of CYP2D6 predictive and measured phenotypes in a South African cohort.
Academic Article Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and Caucasians.
Academic Article Quantification of intraindividual variability and the influence of menstrual cycle phase on CYP2D6 activity as measured by dextromethorphan phenotyping.
Academic Article Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.
Academic Article Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.
Academic Article Limitations of dextromethorphan N-demethylation as a measure of CYP3A activity.
Academic Article Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".
Academic Article Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.

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