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Search Results to Todd Bradley

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research overview Dr. Bradley's research group seeks to understand how immune responses are regulated and to use these tools to engineer immunity. Dysregulation of the immune system can result in an over-stimulated immune response as observed in allergy and autoimmune disorders, or a poor immune response that results in susceptibility to infection and cancer. Dr. Bradley uses genomic technologies to dissect the molecular and cellular mechanisms that shape the immune response and determine how human genetics impacts an individual immunity in order to identify biomarkers and pathways that can be targeted to improve immunotherapies and vaccines. Prior to joining Children's Mercy, Dr. Bradley was Director of Viral Genetic Analysis and Assistant Professor of Medicine at the Human Vaccine Institute at the Duke University Medical Center.

One or more keywords matched the following items that are connected to Bradley, Todd

Item TypeName
Concept Immunity, Cellular
Concept Immunity, Innate
Concept Adaptive Immunity
Concept Immunity, Humoral
Concept Immunity, Heterologous
Academic Article Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.
Academic Article A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge.
Academic Article Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV.
Academic Article Targeting Natural Killer Cells for Improved Immunity and Control of the Adaptive Immune Response.
Academic Article Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors.
Academic Article Cross-reactive antibody immunity against SARS-CoV-2 in children and adults.
Academic Article Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals.
Academic Article Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range.
Grant Impact of Antibody Effector Function Diversity on Antiviral Activity In Situ
Academic Article Humoral and cellular response to the COVID-19 vaccine in immunocompromised children.
Academic Article Host immunity associated with spontaneous suppression of viremia in therapy-na?ve young rhesus macaques following neonatal SHIV infection.

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  • Immunity