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Pastinen, Tomi

One or more keywords matched the following items that are connected to Pastinen, Tomi

Item Type	Name
Concept	DNA Methylation
Academic Article	Epigenetic modification of the gene for the vitamin B(12) chaperone MMACHC can result in increased tumorigenicity and methionine dependence.
Academic Article	Cell culture-induced aberrant methylation of the imprinted IG DMR in human lymphoblastoid cell lines.
Academic Article	Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines.
Academic Article	Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia.
Academic Article	Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.
Academic Article	Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Academic Article	The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts.
Academic Article	Transient DNMT1 suppression reveals hidden heritable marks in the genome.
Academic Article	An epigenome-wide association study of total serum immunoglobulin E concentration.
Academic Article	Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci.
Academic Article	Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Academic Article	Epigenome data release: a participant-centered approach to privacy protection.
Academic Article	High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism.
Academic Article	Bacterial infection remodels the DNA methylation landscape of human dendritic cells.
Academic Article	funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types.
Academic Article	Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation.
Academic Article	DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis.
Academic Article	An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies.
Academic Article	DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.
Academic Article	The International Human Epigenome Consortium Data Portal.
Academic Article	Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.
Academic Article	Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Academic Article	Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.
Academic Article	Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis.
Academic Article	Pioneer factor Pax7 deploys a stable enhancer repertoire for specification of cell fate.
Academic Article	A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data.
Academic Article	Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.
Academic Article	Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes.
Academic Article	H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Academic Article	Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing.
Academic Article	Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism.
Academic Article	Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in na?ve CD4+ T cells.
Academic Article	A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation.
Academic Article	High-resolution analyses of human sperm dynamic methylome reveal thousands of novel age-related epigenetic alterations.
Academic Article	Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation.
Academic Article	Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals.
Academic Article	Epimutations in both the TESK2 and MMACHC promoters in the Epi-cblC inherited disorder of intracellular metabolism of vitamin B12.
Academic Article	Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature.
Academic Article	The Role of Dynamic DNA Methylation in Liver Transplant Rejection in Children.
Academic Article	Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort.
Academic Article	Adverse Maternal Environments Perturb Hepatic DNA Methylome and Transcriptome Prior to the Adult-Onset Non-Alcoholic Fatty Liver Disease in Mouse Offspring.

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DNA Methylation