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Chavez-Bueno, Susana

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Neonatal E. coli sepsis

research overview

Dr. Chavez-Bueno’s current research work focuses on the pathogenesis of E. coli sepsis in newborns. Her overall research goal is to identify novel virulence factors relevant to the pathogen’s ability to traverse the gut and invade the bloodstream causing neonatal sepsis. Her studies utilize in vitro and animal models designed to characterize the bacterial components that determine invasion and trafficking across intestinal epithelium and interact with gut specific immune regulators as potential therapeutic targets to decrease life-threatening neonatal E. coli disease. Dr. Chavez-Bueno is an elected member of the Society for Pediatric Research and member of the Infectious Diseases Society of America.

One or more keywords matched the following items that are connected to Chavez-Bueno, Susana

Item Type	Name
Concept	Escherichia coli
Concept	Escherichia coli Infections
Concept	Escherichia coli Proteins
Academic Article	Genotypic and phenotypic characterization of invasive neonatal Escherichia coli clinical isolates.
Academic Article	Genome Sequence of SCB34, a Sequence Type 131 Multidrug-Resistant Escherichia coli Isolate Causing Neonatal Early-Onset Sepsis.
Academic Article	Whole-Genome Sequences of the Archetypal K1 Escherichia coli Neonatal Isolate RS218 and Contemporary Neonatal Bacteremia Clinical Isolates SCB11, SCB12, and SCB15.
Academic Article	Route of infection alters virulence of neonatal septicemia Escherichia coli clinical isolates.
Academic Article	Antibiotic resistance and molecular characterization of bacteremia Escherichia coli isolates from newborns in the United States.
Grant	Escherichia coli K1 Invasive Infections in Neonates
Grant	Escherichia Coli Colonization in Women in Preterm Labor
Grant	Effects of Probiotics on the Intestinal Microbiome and Inflammatory Response to Infection by Bacteremia-Producing Escherichia coli
Grant	Escherichia coli K1 Invasive Infections in Neonates
Grant	Role of Bacterial Virulence Factors in the Pathogenesis and Host Response to Neonatal Invasive E. coli Infections
Grant	Exposure to low pH Reveals Virulence Factors in Neonatal Escherichia coli Bacteremia after Oral Inoculation
Grant	Bacterial Genes Relevant to Gut Translocation and Virulence in Neonatal Escherichia coli Strains
Grant	Single Immunoglobulin Interleukin-l Related Receptor (SIGIRR) and Escherichia coli Interactions in the Neonatal Gut
Grant	Identification of Virulence Factors in E. coli Strains Causing Neonatal Sepsis
Grant	Role of rfaZ in Pathogenesis of Escherichia coli Neonatal Sepsis
Grant	Escherichia coli Siderophore Receptor IutA as a Virulence Factor in Neonatal Sepsis
Academic Article	Prevalence of Escherichia coli Cervical Colonization in Women in Preterm Labor
Academic Article	Whole-genome sequencing-based phylogeny, antibiotic resistance, and invasive phenotype of Escherichia coli strains colonizing the cervix of women in preterm labor.
Academic Article	Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates.
Academic Article	Evolutionary and functional history of the Escherichia coli K1 capsule.
Grant	Prenatal Lactoferrin to Mitigate Escherichia coli-induced Preterm Delivery and Neonatal Sepsis

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Escherichia coli