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Search Results to Brooke Fridley

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One or more keywords matched the following properties of Fridley, Brooke

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research overview Dr. Fridley joined Children’s Mercy in December of 2023 as the Director of the Biostatistics and Epidemiology Core within the Division of Health Services and Outcomes Research. She is also Professor of Pediatrics at the University of Missouri – Kansas City and is a member of the University of Kansas Cancer Center (KUCC). Before joining Children’s Mercy, she was the Chair of the Department of Biostatistics and Bioinformatics and Scientific Director for the CCSG Biostatistics and Bioinformatics Shared Resource at Moffitt Cancer Center in Tampa, FL. She has extensive experience as a collaborating biostatistician and has worked on numerous cancer research studies over the course of her career. These research collaborations have resulted in over 290 publications and 6 NIH grants for which she was Principal Investigator. She also has extensive experience mentoring trainees and was MPI of a T32 entitled “Integrative Program in Cancer and Data Science” from NIH/NCI. The Fridley lab is focused on development of novel statistical and bioinformatic methods to answer questions that arise in cancer research. Recently, her lab has been working on analytical methods for understanding the spatial architecture of the tumor immune microenvironment and how this is related to clinical outcomes by leveraging the information from spatial single-cell protein and spatial transcriptomic experiments.

One or more keywords matched the following items that are connected to Fridley, Brooke

Item TypeName
Concept Antineoplastic Combined Chemotherapy Protocols
Concept Biopsy
Concept Blood Cell Count
Concept Blood Pressure Determination
Concept Breath Tests
Concept Chromatography, High Pressure Liquid
Concept Chromatography, Thin Layer
Concept Chromosome Mapping
Concept Clinical Trials as Topic
Concept Combined Modality Therapy
Concept Data Collection
Concept Demography
Concept Diagnostic Tests, Routine
Concept DNA Mutational Analysis
Concept Drug Screening Assays, Antitumor
Concept Drug Therapy
Concept Drug Therapy, Combination
Concept Enzyme-Linked Immunosorbent Assay
Concept Family
Concept Feasibility Studies
Concept Fluorescent Antibody Technique
Concept Follow-Up Studies
Concept Genetic Counseling
Concept Genetic Testing
Concept Immunoenzyme Techniques
Concept Immunohistochemistry
Concept Leukocyte Count
Concept Longitudinal Studies
Concept Mammography
Concept Methods
Concept Models, Theoretical
Concept Monte Carlo Method
Concept Neoplasm Staging
Concept Pilot Projects
Concept Prognosis
Concept Prospective Studies
Concept Radiotherapy
Concept Research Design
Concept Risk Management
Concept Sampling Studies
Concept Mass Spectrometry
Concept Statistics as Topic
Concept Tissue Preservation
Concept Transfection
Concept Transplantation, Autologous
Concept Blotting, Western
Concept Cohort Studies
Concept Epidemiologic Research Design
Concept Mastectomy, Segmental
Concept Mastectomy, Subcutaneous
Concept Logistic Models
Concept Epidemiologic Studies
Concept Case-Control Studies
Concept Liver Transplantation
Concept Polymerase Chain Reaction
Concept Mutagenesis, Site-Directed
Concept Mammaplasty
Concept Chemotherapy, Adjuvant
Concept Clinical Trials, Phase I as Topic
Concept Clinical Trials, Phase II as Topic
Concept Clinical Trials, Phase III as Topic
Concept In Situ Hybridization, Fluorescence
Concept Sequence Analysis, DNA
Concept Sequence Analysis, RNA
Concept Hematopoietic Stem Cell Transplantation
Concept Risk Assessment
Concept Patient Selection
Concept Radiotherapy, Adjuvant
Concept Coculture Techniques
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Neoadjuvant Therapy
Concept Oligonucleotide Array Sequence Analysis
Concept Gene Expression Profiling
Concept Electrophoretic Mobility Shift Assay
Concept Stem Cell Transplantation
Concept Tissue Array Analysis
Concept Chromatin Immunoprecipitation
Concept Early Detection of Cancer
Concept Genome-Wide Association Study
Concept Gene Knockdown Techniques
Concept Drug Discovery
Concept Genetic Association Studies
Concept Mendelian Randomization Analysis
Concept Delayed Diagnosis
Concept Precision Medicine
Concept Single-Cell Analysis
Concept High-Throughput Nucleotide Sequencing
Concept HapMap Project
Concept Neoplasm Grading
Concept Real-Time Polymerase Chain Reaction
Concept Public Health Surveillance
Concept Patient Outcome Assessment
Academic Article Multi-omics Data Deconvolution and Integration: New Methods, Insights, and Translational Implications.
Academic Article A Primer on Preprocessing, Visualization, Clustering, and Phenotyping of Barcode-Based Spatial Transcriptomics Data.
Academic Article Statistical Methods for Integrative Clustering of Multi-omics Data.
Academic Article Integrative clustering methods for high-dimensional molecular data.
Academic Article InterSIM: Simulation tool for multiple integrative 'omic datasets'.
Academic Article Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments.
Academic Article Statistics and Machine Learning in Mass Spectrometry-Based Metabolomics Analysis.
Academic Article Diagnostic tools in linkage analysis for quantitative traits.
Academic Article Imputation methods for missing data for polygenic models.
Academic Article Missing phenotype data imputation in pedigree data analysis.
Academic Article Model selection and Bayesian methods in statistical genetics: summary of group 11 contributions to Genetic Analysis Workshop 15.
Academic Article The genetics of gene expression: comparison of linkage scans using two phenotype normalization methods.
Academic Article Comparison of variable and model selection methods for genetic association studies using the GAW15 simulated data.
Academic Article Comparison of tagging single-nucleotide polymorphism methods in association analyses.
Academic Article Bayesian variable and model selection methods for genetic association studies.
Academic Article Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group.
Academic Article A Bayesian hierarchical nonlinear model for assessing the association between genetic variation and drug cytotoxicity.
Academic Article Assessment of genotype imputation methods.
Academic Article Localizing putative markers in genetic association studies by incorporating linkage disequilibrium into bayesian hierarchical models.
Academic Article Bayesian mixture models for the incorporation of prior knowledge to inform genetic association studies.
Academic Article Self-contained gene-set analysis of expression data: an evaluation of existing and novel methods.
Academic Article Use of the gamma method for self-contained gene-set analysis of SNP data.
Academic Article A Bayesian integrative genomic model for pathway analysis of complex traits.

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