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Search Results to Laura Ramsey

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research overview Dr. Ramsey joined Children’s Mercy in 2023 as the Section Chief of Individualized Therapeutics in the Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation. She is leading the implementation of a pharmacogenomics program that is fully integrated with the electronic health record, and she is developing model-informed decision support for several medications. Before joining Children’s Mercy, Dr. Ramsey was an Associate Professor at Cincinnati Children’s Hospital Medical Center, co-director of the Genetic Pharmacology Service, and co-director of the Clinical Pharmacology Fellowship program. She completed her postdoctoral fellowship in Pharmacogenetics at St. Jude Children’s Research Hospital and received her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota – Twin Cities. Dr. Ramsey is interested in all aspects of pharmacogenetics, from basic research to implementation in patient care. She has led projects to study pharmacogenetic variants that influence response, toxicity, and dosing of antidepressants, immunosuppressants, and chemotherapy in children. She has authored over 100 peer-reviewed manuscripts, hundreds of abstract presentations, and is extramurally funded, including a National Institutes of Health R01 award.

One or more keywords matched the following items that are connected to Ramsey, Laura

Item TypeName
Concept Treatment Outcome
Concept Enzyme Replacement Therapy
Concept Precision Medicine
Academic Article A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy.
Academic Article Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.
Academic Article The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.
Academic Article Pharmacogenomics of acute lymphoid leukemia: new insights into treatment toxicity and efficacy.
Academic Article Severe hypertriglyceridaemia during therapy for childhood acute lymphoblastic leukaemia.
Academic Article Effect of premedications in a murine model of asparaginase hypersensitivity.
Academic Article Genome-wide analysis links NFATC2 with asparaginase hypersensitivity.
Academic Article Learning Health Systems as Facilitators of Precision Medicine.
Academic Article Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy.
Academic Article Impact of Pharmacogenetics on Efficacy and Safety of Statin Therapy for Dyslipidemia.
Academic Article Implementation of Pharmacogenetics at Cincinnati Children's Hospital Medical Center: Lessons Learned Over 14 Years of Personalizing Medicine.
Academic Article Interpreting and Implementing Clinical Pharmacogenetic Tests: Perspectives From Service Providers.
Academic Article Gene-Based Dose Optimization in Children.
Academic Article Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia.
Academic Article Cariprazine in Youth with Bipolar and Psychotic Disorders: A Retrospective Chart Review.
Academic Article The Influence of Pharmacodynamic Genes on Fluoxetine Response in Pediatric Anxiety and Depressive Disorders.
Academic Article Novel pharmacological treatments for generalized anxiety disorder: Pediatric considerations.
Academic Article Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care.
Academic Article Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study.
Academic Article Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients.
Academic Article The Impact of Marijuana on Antidepressant Treatment in Adolescents: Clinical and Pharmacologic Considerations.
Academic Article Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.
Academic Article Advancing Precision Medicine Through the New Pharmacogenomics Global Research Network.
Academic Article Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy.
Academic Article Pediatric Therapeutic Drug Monitoring for Selective Serotonin Reuptake Inhibitors.
Academic Article Pharmacogenetically Guided Escitalopram Treatment for Pediatric Anxiety Disorders: Protocol for a Double-Blind Randomized Trial.
Academic Article Best-worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy.
Academic Article Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing.
Academic Article Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center.
Award or Honor Receipt Darrell Abernethy Early Stage Investigator Award
Grant Identifying Pharmacogenomic Predictors of Methotrexate Response and Metabolite Biotransformation in JIA

Search Criteria
  • Precision
  • Therapeutics