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Search Results to Laura Ramsey

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research overview Dr. Ramsey joined Children’s Mercy in 2023 as the Section Chief of Individualized Therapeutics in the Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation. She is leading the implementation of a pharmacogenomics program that is fully integrated with the electronic health record, and she is developing model-informed decision support for several medications. Before joining Children’s Mercy, Dr. Ramsey was an Associate Professor at Cincinnati Children’s Hospital Medical Center, co-director of the Genetic Pharmacology Service, and co-director of the Clinical Pharmacology Fellowship program. She completed her postdoctoral fellowship in Pharmacogenetics at St. Jude Children’s Research Hospital and received her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota – Twin Cities. Dr. Ramsey is interested in all aspects of pharmacogenetics, from basic research to implementation in patient care. She has led projects to study pharmacogenetic variants that influence response, toxicity, and dosing of antidepressants, immunosuppressants, and chemotherapy in children. She has authored over 100 peer-reviewed manuscripts, hundreds of abstract presentations, and is extramurally funded, including a National Institutes of Health R01 award.

One or more keywords matched the following items that are connected to Ramsey, Laura

Item TypeName
Concept Hospitals, Pediatric
Concept Pediatrics
Concept Treatment Outcome
Concept Enzyme Replacement Therapy
Concept Precision Medicine
Grant Children's Mercy Hospital Collaborative Fellowship Program in Pediatric Pharmacology
Academic Article A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy.
Academic Article Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.
Academic Article The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.
Academic Article Pharmacogenomics of acute lymphoid leukemia: new insights into treatment toxicity and efficacy.
Academic Article Severe hypertriglyceridaemia during therapy for childhood acute lymphoblastic leukaemia.
Academic Article Effect of premedications in a murine model of asparaginase hypersensitivity.
Academic Article Genome-wide analysis links NFATC2 with asparaginase hypersensitivity.
Academic Article Learning Health Systems as Facilitators of Precision Medicine.
Academic Article Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy.
Academic Article Impact of Pharmacogenetics on Efficacy and Safety of Statin Therapy for Dyslipidemia.
Academic Article Implementation of Pharmacogenetics at Cincinnati Children's Hospital Medical Center: Lessons Learned Over 14 Years of Personalizing Medicine.
Academic Article CYP2C19-Guided Escitalopram and Sertraline Dosing in Pediatric Patients: A Pharmacokinetic Modeling Study.
Academic Article Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive Disorders.
Academic Article Interpreting and Implementing Clinical Pharmacogenetic Tests: Perspectives From Service Providers.
Academic Article Gene-Based Dose Optimization in Children.
Academic Article Pharmacogenetics of treating pediatric anxiety and depression.
Academic Article Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia.
Academic Article Cariprazine in Youth with Bipolar and Psychotic Disorders: A Retrospective Chart Review.
Academic Article The Influence of Pharmacodynamic Genes on Fluoxetine Response in Pediatric Anxiety and Depressive Disorders.
Academic Article Novel pharmacological treatments for generalized anxiety disorder: Pediatric considerations.
Academic Article Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care.
Academic Article CYP2D6 Phenotype Influences Aripiprazole Tolerability in Pediatric Patients with Mood Disorders.
Academic Article Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study.
Academic Article Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients.
Academic Article Characterizing Pharmacogenetic Testing Among Children's Hospitals.
Academic Article Acute Neurofunctional Effects of Escitalopram in Pediatric Anxiety: A Double-Blind, Placebo-Controlled Trial.
Academic Article Perspectives from the Society for Pediatric Research: pharmacogenetics for pediatricians.
Academic Article Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies.
Academic Article The Impact of Marijuana on Antidepressant Treatment in Adolescents: Clinical and Pharmacologic Considerations.
Academic Article Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.
Academic Article Advancing Precision Medicine Through the New Pharmacogenomics Global Research Network.
Academic Article SLCO1B1 *15 allele is associated with methotrexate-induced nausea in pediatric patients with inflammatory bowel disease.
Academic Article Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy.
Academic Article Pediatric Therapeutic Drug Monitoring for Selective Serotonin Reuptake Inhibitors.
Academic Article Influence of CYP2D6 metabolizer status on ondansetron efficacy in pediatric patients undergoing hematopoietic stem cell transplantation: A case series.
Academic Article Pharmacogenetically Guided Escitalopram Treatment for Pediatric Anxiety Disorders: Protocol for a Double-Blind Randomized Trial.
Academic Article Best-worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy.
Academic Article Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing.
Academic Article Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center.
Academic Article Pediatric Psychopharmacology for Depressive and Anxiety Disorders.
Academic Article Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients.
Academic Article Enhancing pharmacokinetic and pharmacodynamic knowledge in pediatrics.
Academic Article Current Practices in Pharmacogenomics.
Academic Article Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients.
Award or Honor Receipt Darrell Abernethy Early Stage Investigator Award
Grant Improving the Effectiveness and Safety of Escitalopram in Pediatric Anxiety Disorders Using Pharmacogenetically-guided Dosing
Grant Identifying Pharmacogenomic Predictors of Methotrexate Response and Metabolite Biotransformation in JIA
Academic Article From Dose to Exposure: Shifting the Paradigm of Pediatric Clinical Pharmacology Research and Education.
Academic Article Pharmacogenetic testing in primary care could bolster depression treatment: A value proposition.
Academic Article Optimizing early phase clinical trial washout periods: a report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium.

Search Criteria
  • Pediatric
  • Precision
  • Therapeutics