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Search Results to Jay Vivian

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One or more keywords matched the following properties of Vivian, Jay

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keywords Pluripotent Stem Cells
research overview Dr. Vivian's research uses the mouse and pluripotent stem cells as genetic models of disease, to understand the basis of various disorders and for therapeutic discovery. These efforts leverage expertise in stem cell biology, mouse experimental genetics, molecular biology, genetic engineering, and developmental biology. A major focus of his lab involves the development and analysis of animal and pluripotent stem cell models of rare pediatric congenital disorders, using the genetic data mapped by human genetics studies focused on pediatric neurological disorders. These collaborative translational efforts make substantial use of genome editing to engineer genetically modified mice and patient-specific induced pluripotent stem cells for therapeutic discovery.

One or more keywords matched the following items that are connected to Vivian, Jay

Item TypeName
Concept Human Embryonic Stem Cells
Concept Hematopoietic Stem Cells
Concept Stem Cells
Concept Computational Biology
Concept Embryonic Stem Cells
Concept Induced Pluripotent Stem Cells
Concept Neural Stem Cells
Academic Article Fate of Neural Progenitor Cells Transplanted Into Jaundiced and Nonjaundiced Rat Brains.
Academic Article Transforming growth factor-beta superfamily in mouse embryonic stem cell self-renewal.
Academic Article Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment.
Academic Article TGF-?-superfamily signaling regulates embryonic stem cell heterogeneity: self-renewal as a dynamic and regulated equilibrium.
Academic Article Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis.
Academic Article OVO-like 1 regulates progenitor cell fate in human trophoblast development.
Academic Article Short Term Development and Fate of MGE-Like Neural Progenitor Cells in Jaundiced and Non-Jaundiced Rat Brain.
Academic Article Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice.
Academic Article Reprogramming of Primary Human Cells to Induced Pluripotent Stem Cells Using Sendai Virus.
Academic Article An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells.
Academic Article Gene-based chemical mutagenesis in mouse embryonic stem cells.
Academic Article ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development.
Academic Article Activation of the VEGFR1 chromatin domain: an angiogenic signal-ETS1/HIF-2alpha regulatory axis.
Academic Article Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cells.
Academic Article Early mammalian erythropoiesis requires the Dot1L methyltransferase.
Grant Hippo Signaling Effector and Placentation
Grant Cancer Center Support Grant
Academic Article DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin.
Academic Article MGE-Like Neural Progenitor Cell Survival and Expression of Parvalbumin and Proenkephalin in a Jaundiced Rat Model of Kernicterus.
Grant Induced pluripotent stem cell models for pediatric KMT2A-r leukemia development and discovery or targeted therapies
Grant A CRISPR genetic screen in an induced pluripotent stem cell model to discover modifiers of therapy-related pediatric leukemia

Search Criteria
  • Stem Cell
  • Biology