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Search Results to Jay Vivian

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research overview Dr. Vivian's research uses the mouse and pluripotent stem cells as genetic models of disease, to understand the basis of various disorders and for therapeutic discovery. These efforts leverage expertise in stem cell biology, mouse experimental genetics, molecular biology, genetic engineering, and developmental biology. A major focus of his lab involves the development and analysis of animal and pluripotent stem cell models of rare pediatric congenital disorders, using the genetic data mapped by human genetics studies focused on pediatric neurological disorders. These collaborative translational efforts make substantial use of genome editing to engineer genetically modified mice and patient-specific induced pluripotent stem cells for therapeutic discovery.

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  • Pediatric
  • Clinical Pharmacology