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Search Results to Jay Vivian

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One or more keywords matched the following properties of Vivian, Jay

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keywords Drug Screening
research overview Dr. Vivian's research uses the mouse and pluripotent stem cells as genetic models of disease, to understand the basis of various disorders and for therapeutic discovery. These efforts leverage expertise in stem cell biology, mouse experimental genetics, molecular biology, genetic engineering, and developmental biology. A major focus of his lab involves the development and analysis of animal and pluripotent stem cell models of rare pediatric congenital disorders, using the genetic data mapped by human genetics studies focused on pediatric neurological disorders. These collaborative translational efforts make substantial use of genome editing to engineer genetically modified mice and patient-specific induced pluripotent stem cells for therapeutic discovery.

One or more keywords matched the following items that are connected to Vivian, Jay

Item TypeName
Concept Arabinofuranosyluracil
Concept Base Sequence
Concept Benzamides
Concept beta-Galactosidase
Concept Bilirubin
Concept Calcium
Concept Calcium, Dietary
Concept Choline O-Acetyltransferase
Concept Chromatin
Concept Codon
Concept Deoxyribonucleases
Concept Desmin
Concept Dioxoles
Concept Diphenylamine
Concept DNA-Binding Proteins
Concept Enkephalins
Concept Erythropoietin
Concept Ethylnitrosourea
Concept Exons
Concept Embryonic and Fetal Development
Concept Fibroblast Growth Factors
Concept gamma-Aminobutyric Acid
Concept Glutamate Decarboxylase
Concept Glycoproteins
Concept Gonadotropins
Concept Histocompatibility Antigens
Concept Histones
Concept Hypoxanthine Phosphoribosyltransferase
Concept Luteinizing Hormone
Concept Membrane Proteins
Concept Methyltransferases
Concept Muscle Proteins
Concept Parvalbumins
Concept Pregnancy Proteins
Concept Progesterone
Concept Prolactin
Concept Promoter Regions, Genetic
Concept Protein Kinase C
Concept Histone-Lysine N-Methyltransferase
Concept Protein Precursors
Concept Proto-Oncogene Proteins
Concept Receptors, Cell Surface
Concept Ribosomal Proteins
Concept RNA, Messenger
Concept Thymidine Kinase
Concept Transcription Factors
Concept Trans-Activators
Concept Mifepristone
Concept Cell Adhesion Molecules
Concept Transforming Growth Factor beta
Concept RNA-Binding Proteins
Concept Receptors, Erythropoietin
Concept MyoD Protein
Concept DNA Primers
Concept Myogenic Regulatory Factors
Concept Myogenin
Concept Codon, Nonsense
Concept Homeodomain Proteins
Concept Gene Expression Regulation, Developmental
Concept Vascular Cell Adhesion Molecule-1
Concept Bone Morphogenetic Proteins
Concept Protein Isoforms
Concept Muscle Development
Concept RNA, Small Interfering
Concept Intercellular Signaling Peptides and Proteins
Concept Vascular Endothelial Growth Factor Receptor-1
Concept Vascular Endothelial Growth Factor A
Concept Embryonic Development
Concept Fetal Development
Concept Estrogen Receptor alpha
Concept Estrogen Receptor beta
Concept MAP Kinase Kinase 1
Concept Adaptor Proteins, Signal Transducing
Concept Green Fluorescent Proteins
Concept TRPC Cation Channels
Concept Proto-Oncogene Protein c-ets-1
Concept GATA2 Transcription Factor
Concept GATA3 Transcription Factor
Concept Fibroblast Growth Factor 4
Concept Basic Helix-Loop-Helix Transcription Factors
Concept Receptors, Notch
Concept Smad1 Protein
Concept Smad2 Protein
Concept Smad4 Protein
Concept Smad5 Protein
Concept Smad7 Protein
Concept Hedgehog Proteins
Concept Bone Morphogenetic Protein 4
Concept Nodal Protein
Concept Left-Right Determination Factors
Academic Article Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac.
Academic Article Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment.
Academic Article OVO-like 1 regulates progenitor cell fate in human trophoblast development.
Academic Article Tipping the balance toward trophoblast development.
Academic Article Short Term Development and Fate of MGE-Like Neural Progenitor Cells in Jaundiced and Non-Jaundiced Rat Brain.
Academic Article Myogenin is required for late but not early aspects of myogenesis during mouse development.
Academic Article Wild-type myoblasts rescue the ability of myogenin-null myoblasts to fuse in vivo.
Academic Article A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation.
Academic Article Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice.
Academic Article In Vivo Validation of CRISPR Reagents in Preimplantation Mouse Embryos.
Academic Article Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.
Academic Article Global growth deficiencies in mice lacking the ribosomal protein HIP/RPL29.
Academic Article ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development.
Academic Article Early mammalian erythropoiesis requires the Dot1L methyltransferase.
Grant Hippo Signaling Effector and Placentation
Grant Cancer Center Support Grant
Grant A novel drug screen for therapies for Vici Syndrome

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