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Search Results to Alain C. Cuna

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research overview Dr. Cuna's main research interest is on defining the pathogenesis of necrotizing enterocolitis (NEC) – a devastating inflammatory bowel disease of preterm infants - and translating this knowledge to improve outcomes of NEC. His current focus is on understanding how host genetics and intestinal bacterial communities interact with each other to modulate inflammation in the developing neonatal gut. New knowledge gained from this research is anticipated to help in the development of personalized, microbial-based therapies based on underlying genetic predisposition and/or gut microbiome signatures to help maintain gut homeostasis. Such novel, individualized therapies are expected to drastically reduce the incidence of NEC in a safe and effective manner by targeting infants at highest risk of the disease.

One or more keywords matched the following items that are connected to Cuna, Alain

Item TypeName
Concept Intensive Care Units, Neonatal
Concept Intensive Care, Neonatal
Academic Article Neonatal Graves' Disease with Maternal Hypothyroidism.
Academic Article Genetic predisposition to necrotizing enterocolitis in premature infants: Current knowledge, challenges, and future directions.
Academic Article NEC-like intestinal injury is ameliorated by Lactobacillus rhamnosus GG in parallel with SIGIRR and A20 induction in neonatal mice.
Academic Article Implementation of bowel ultrasound practice for the diagnosis and management of necrotising enterocolitis.
Academic Article A randomised trial of re-feeding gastric residuals in preterm infants.
Academic Article Quality Improvement Project to Reduce Delayed Vaccinations in Preterm Infants.
Grant Gene-environment interactions in necrotizing enterocolitis: impact of SIGIRR mutation and gut microbiota on intestinal TLR hyperactivity
Academic Article Dynamics of the preterm gut microbiome in health and disease.
Academic Article A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children's Hospitals Neonatal Consortium Severe BPD Group.
Academic Article Chronic lung disease in full-term infants: Characteristics and neonatal intensive care outcomes in infants referred to children's hospitals.
Grant Multicenter Comparative Effectiveness Trial of Bowel Ultrasound for Diagnosis of Necrotizing Enterocolitis (NEC)
Academic Article The Detrimental Effects of Peripartum Antibiotics on Gut Proliferation and Formula Feeding Injury in Neonatal Mice Are Alleviated with Lactobacillus rhamnosus GG.
Academic Article Current Patterns of Probiotic Use in U.S. Neonatal Intensive Care Units: A Multi-Institution Survey.

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