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Search Results to Alain C. Cuna

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One or more keywords matched the following properties of Cuna, Alain

keywords Necrotizing Enterocolitis
research overview Dr. Cuna's main research interest is on defining the pathogenesis of necrotizing enterocolitis (NEC) – a devastating inflammatory bowel disease of preterm infants - and translating this knowledge to improve outcomes of NEC. His current focus is on understanding how host genetics and intestinal bacterial communities interact with each other to modulate inflammation in the developing neonatal gut. New knowledge gained from this research is anticipated to help in the development of personalized, microbial-based therapies based on underlying genetic predisposition and/or gut microbiome signatures to help maintain gut homeostasis. Such novel, individualized therapies are expected to drastically reduce the incidence of NEC in a safe and effective manner by targeting infants at highest risk of the disease.

One or more keywords matched the following items that are connected to Cuna, Alain

Item TypeName
Concept Enterocolitis, Necrotizing
Academic Article Genetic alterations in necrotizing enterocolitis.
Academic Article Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4-mediated necrotizing enterocolitis in a mouse model.
Academic Article Bowel ultrasound for predicting surgical management of necrotizing enterocolitis: a systematic review and meta-analysis.
Academic Article Bowel Ultrasound for the Diagnosis of Necrotizing Enterocolitis: A Meta-analysis.
Academic Article Genetic predisposition to necrotizing enterocolitis in premature infants: Current knowledge, challenges, and future directions.
Academic Article NEC-like intestinal injury is ameliorated by Lactobacillus rhamnosus GG in parallel with SIGIRR and A20 induction in neonatal mice.
Academic Article Implementation of bowel ultrasound practice for the diagnosis and management of necrotising enterocolitis.
Academic Article A randomised trial of re-feeding gastric residuals in preterm infants.
Grant Gene-environment interactions in necrotizing enterocolitis: impact of SIGIRR mutation and gut microbiota on intestinal TLR hyperactivity
Academic Article Dynamics of the preterm gut microbiome in health and disease.
Academic Article Racial Disparities in Necrotizing Enterocolitis.
Academic Article Feasibility and acceptability of a diagnostic randomized clinical trial of bowel ultrasound in infants with suspected necrotizing enterocolitis.
Grant Multicenter Comparative Effectiveness Trial of Bowel Ultrasound for Diagnosis of Necrotizing Enterocolitis (NEC)
Academic Article Imaging for Diagnosis and Assessment of Necrotizing Enterocolitis.
Academic Article Necrotizing enterocolitis in premature infants-A defect in the brakes? Evidence from clinical and animal studies.
Academic Article Early antibiotics and risk for necrotizing enterocolitis in premature infants: A narrative review.
Academic Article Degree of Uncertainty in Reporting Imaging Findings for Necrotizing Enterocolitis: A Secondary Analysis from a Pilot Randomized Diagnostic Trial.

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  • Necrotizing Enterocolitis