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Search Results to Jonathan B. Wagner

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One or more keywords matched the following properties of Wagner, Jonathan

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keywords Pediatric Cardiology
keywords Pediatric Clinical Pharmacology
preferred title Physician and Interim Division Director, Clinical Pharmacology, Toxicology & Therapeutic Innovation
research overview Jon Wagner, DO, FAAP, graduated with a Bachelor of Science degree in biochemistry with cum laude latin honors from the University of Missouri-Columbia and received his medical degree with magna cum laude honors from Kansas City University College of Osteopathic Medicine. He completed pediatrics residency at Children’s Mercy Kansas City (CMKC), followed by a dual fellowship training in pediatric cardiology and pediatric clinical pharmacology. Dr. Wagner joined Children’s Mercy Kansas City faculty in 2013. He currently holds an academic rank of Associate Professor of Pediatrics at University of Missouri-Kansas City School of Medicine. He is the division director of Clinical Pharmacology and Toxicology at CMKC. His early career research involved the impact of genetic variation and development on statin disposition during childhood. His series of pharmacogenomics driven pharmacokinetic studies involving statins has contributed to further understanding of inter-individual variability of statin response in the pediatric population. Dr. Wagner has served as a site-primary investigator for the Fontan Udenafil Exercise Longitudinal (FUEL) and Fontan Associated Liver Disease (FALD) trials sponsored by the Pediatric Heart Network (NHLBI). He is the primary investigator of the IMProving Drug dosing and Outcomes for single Ventricle patients with Fontan Associated Liver Disease (IMPROVE-FALD) research program at Children’s Mercy Kansas. He has been the director of the Cardiology Pharmacogenomics Repository (CPR) at CMKC since 2013. Dr. Wagner has previously been honored as the 2018 CMKC Department of Pediatrics Research Achievement Award and 2022 Kansas City University Alumnus of the Year Award. He holds the Matson Family Endowed Professorship in Cardiac Research at CMKC. He has received over 3 million dollars in external funding during his career from the American Heart Association, Thrasher Research Fund, and the National Institutes of Health (NIH) to support his research and fellowship programs involving pediatric cardiovascular disease and pediatric clinical pharmacology. Dr. Wagner serves on the Advisory Council on Rare Disease and Personalized Medicine for Missouri Health Net division of the Missouri Department of Social Services and was a past member of American Heart Association Kansas City Board of Directors. Dr. Wagner’s passion and research goals involve clinical integration of pharmacogenomics, pathophysiology, and precision medicine into routine cardiovascular care, but simultaneously is passionate about spending quality time with his wife (Margo) and 2 boys (Oliver and Teddy) when not busy at work.

One or more keywords matched the following items that are connected to Wagner, Jonathan

Item TypeName
Concept Pediatrics
Concept Pediatric Obesity
Academic Article Pediatric pharmacogenomics: a systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children.
Academic Article Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study.
Academic Article Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics.
Academic Article Pediatric pharmacokinetics.
Academic Article Oseltamivir-warfarin interaction in hypoplastic left heart syndrome: case report and review.
Academic Article Pediatric Statin Administration: Navigating a Frontier with Limited Data.
Academic Article Impact of Genetic Variation on Pravastatin Systemic Exposure in Pediatric Hypercholesterolemia.
Academic Article Drug Dose Selection in Pediatric Obesity: Available Information for the Most Commonly Prescribed Drugs to Children.
Academic Article Impact of SLCO1B1 Genetic Variation on Rosuvastatin Systemic Exposure in Pediatric Hypercholesterolemia.
Academic Article Children Are Not Small Adults: Specific Findings in Statin Exposure and Response in a Growing Population.
Grant Statin Optimization in Pediatrics
Grant Cardiology Pharmacogenomics Repository
Grant Pharmacokinetics of pravastatin and simvastatin in pediatric dyslipidemia patients: Clinical impact of genetic variation in statin disposition
Grant Pharmacokinetics of pravastatin and simvastatin in pediatric dyslipidemia patients: Clinical impact of genetic variation in statin disposition
Grant Pharmacokinetics of pravastatin and simvastatin in pediatric dyslipidemia patients: Clinical impact of genetic variation in statin disposition
Grant Pharmacokinetics of rosuvastatin and atorvastatin in pediatric dyslipidemia patients: Clinical impact of genetic variation in statin disposition
Academic Article Critical need for pharmacologic treatment options in NAFLD: A pediatric perspective.
Academic Article Efficacy of Weight Reduction on Pediatric Nonalcoholic Fatty Liver Disease: Opportunities to Improve Treatment Outcomes Through Pharmacotherapy.
Award or Honor Receipt Department of Pediatrics Research Achievement Award
Award or Honor Receipt Mary Colleen Alderman Excellence in Pediatric Finalist
Grant Effects of Pediatric Liver Adiposity on Statin Disposition and Response
Grant Children’s Mercy Hospital Collaborative Fellowship Program in Pediatric Pharmacology
Academic Article In Tsongalis G eds. Advances in Molecular Pathology
Academic Article Peak Oxygen Consumption (V?O 2peak ) Recovery Delay in a Pediatric Fontan Population.
Academic Article Pediatric Pharmacogenetics and Pharmacogenomics, and Pharmacoproteomics. In Nelson’s Textbook of Pediatrics, 21st edition, Kliegman RM, Stanton BF, St. Geme III JW, Schor NF, Behrman RE, (Eds
Academic Article SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia.
Academic Article Pediatric Beta Blocker Therapy: A Comprehensive Review of Development and Genetic Variation to Guide Precision-Based Therapy in Children, Adolescents, and Young Adults.

Search Criteria
  • Pediatric
  • Clinical Pharmacology