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Search Results to Robert H. Lane

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One or more keywords matched the following properties of Lane, Robert

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keywords Epigenetics
research overview Dr. Lane’s research program focuses upon on how perinatal events affect in vivo epigenetic determinants of gene expression and lead to adult disease. In 1996, Dr. Lane published his first original science manuscript on this focus, and he has remained committed to the topic. Indeed, the vast majority of his > 90 publications are devoted to how perinatal events lead to adult disease. In 2003, Dr. Lane published his first original science manuscript on how perinatal events impact in vivo epigenetics. This study stands among the earliest to demonstrate that a perinatal event affected the epigenetics of a specific gene. Dr. Lane also has a track record of NIH funding as P.I. and a Co-I, the latter demonstrating his willingness to enthusiastically engage in team science. In 2013, Dr. Lane accepted the position of Pediatrician in Chief and Chair of Pediatrics at Children’s Hospital of Wisconsin. This move required Dr. Lane to move his laboratory. Yet, despite the move and the job requirements, Dr. Lane has maintained his scholarly productivity. In 2020, Dr. Lane accepted the position of Executive Vice President /Physician in Chief at Children’s Mercy in Kansas City. Dr. Lane has actively participated in the US Developmental Origins and Health and Disease Society. He has served as the scientific program officer for 2018 and 2019. In 2019, he was elected President of the Society. Dr. Lane’s laboratory has continued to be productive scientifically publishing papers in 2018 and 2019. Dr. Lane also chaired the NIH Social Epigenomics Study Section in 2020. His laboratory will move from Milwaukee to Kansas City in 6/2020 pending the impact of COVID-19.

One or more keywords matched the following items that are connected to Lane, Robert

Item TypeName
Concept Epigenomics
Grant Uteroplacental Insufficiency Alters DNA Methylation
Grant Maternal Diet Modifies the Fetal Primate Epigenome and Circadian Gene Expression
Academic Article Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats.
Academic Article Growth retardation alters the epigenetic characteristics of hepatic dual specificity phosphatase 5.
Academic Article Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene.
Academic Article Epigenetics and fetal adaptation to perinatal events: diversity through fidelity.
Academic Article Intrauterine growth retardation affects expression and epigenetic characteristics of the rat hippocampal glucocorticoid receptor gene.
Academic Article Fetal growth restriction alters transcription factor binding and epigenetic mechanisms of renal 11beta-hydroxysteroid dehydrogenase type 2 in a sex-specific manner.
Academic Article Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth.
Academic Article Intrauterine growth restriction affects hippocampal dual specificity phosphatase 5 gene expression and epigenetic characteristics.
Academic Article Epigenetics and the developmental origins of lung disease.
Academic Article Stem cell DNA methylation: a consequence of intrauterine growth restriction.
Academic Article Intrauterine growth restriction, neural microRNA expression and hypertension in the mouse.
Academic Article Placental variability in methylation reflects maternal and fetal pathogenesis.
Academic Article Intrauterine growth restriction disturbs mediators of placental protein turnover.
Academic Article Traumatic brain injury increased IGF-1B mRNA and altered IGF-1 exon 5 and promoter region epigenetic characteristics in the rat pup hippocampus.
Academic Article Epigenetics and the developmental origins of disease: the key to unlocking the door of personalized medicine.
Academic Article Epigenetic mechanisms in fetal origins of health and disease.
Academic Article Epigenetics: where environment, society and genetics meet.
Academic Article Fetal programming, epigenetics, and adult onset disease.
Academic Article Intrauterine growth restriction disrupts developmental epigenetics around distal growth hormone response elements on the rat hepatic IGF-1 gene.
Academic Article Epigenetic contributions to the developmental origins of adult lung disease.
Academic Article The relationship between early-life environment, the epigenome and the microbiota.
Academic Article Persistent pulmonary hypertension alters the epigenetic characteristics of endothelial nitric oxide synthase gene in pulmonary artery endothelial cells in a fetal lamb model.
Academic Article Epigenetics: an accessible mechanism through which to track and respond to an obesogenic environment.
Grant Epigenetic Modulation of the PPARgamma Transcription in the IUGR Rat
Grant Epigenetics Participate in Neonatal CLD
Academic Article Hippocampal epigenetic and insulin-like growth factor alterations in noninvasive versus invasive mechanical ventilation in preterm lambs.
Academic Article Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus
Academic Article Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus.
Academic Article Adverse maternal environment affects hippocampal HTR2c variant expression and epigenetic characteristics in mouse offspring.

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  • Epigenomics