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Search Results to Elin Grundberg

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One or more keywords matched the following properties of Grundberg, Elin

PropertyValue
keywords Complex diseases
keywords Metabolic diseases
research overview Dr. Elin Grundberg completed her PhD (2006) in Molecular Medicine at Uppsala University, Sweden and following post-doctoral training at the McGill University and Genome Quebec Innovation Centre she joined Wellcome Trust Sanger institute in 2009 to lead the international MuTHER Consortium, which included developing a major resource of detailed genomics and epigenomics data from multiple disease-targeted tissues from twins. In 2012, she was appointed Tenure-Track Assistant Professor at the Department of Human Genetics at McGill University where her group was applying various next-generation sequencing approaches to understand genetic and epigenetic factors underlying complex disease susceptibility. Dr. Grundberg lead two CIHR team grants on this topic including the EpiTriO Consotium with partners in Canada and Europe. She held a Canada Research Chair (tier 2) in Disease Genomics and Epigenomics. In Oct 2017, Dr. Grundberg joined the faculty at Children’s Mercy Kansas City where she holds the Roberta D. Harding & William F. Bradley, Jr. Endowed Chair in Genomic Research. She is building a comprehensive research program leveraging international collaborations (King’s College London, UK; INSERM, France, Helmholtz Zentrum, Germany, McGill, Canada) as well as local collaborators (CM, UMKC, KUMC) for tissue-resources and methodologies essential for contemporary disease genomics and epigenomics. Research areas span genomics medicine applied in pediatric and adult populations including rare diseases, metabolic diseases, social and environmental health and perinatal/maternal health. Dr. Grundberg currently collaborates with a number of large international research consortia and is the author of over 75 scientific papers.

One or more keywords matched the following items that are connected to Grundberg, Elin

Item TypeName
Concept Autoimmune Diseases
Concept Bone Diseases, Developmental
Concept Bone Diseases, Metabolic
Concept Cardiovascular Diseases
Concept Chronic Disease
Concept Coronary Artery Disease
Concept Coronary Disease
Concept Disease Models, Animal
Concept Metabolic Diseases
Concept Genetic Predisposition to Disease
Concept Rare Diseases
Concept Actin-Related Protein 2-3 Complex
Academic Article Population genomics in a disease targeted primary cell model.
Academic Article Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.
Academic Article A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.
Academic Article An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.
Academic Article Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Academic Article Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Academic Article Large-scale association analysis identifies new risk loci for coronary artery disease.
Academic Article Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Academic Article Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.
Academic Article Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Academic Article Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Academic Article Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.
Academic Article The impact of estradiol on bone mineral density is modulated by the specific estrogen receptor-alpha cofactor retinoblastoma-interacting zinc finger protein-1 insertion/deletion polymorphism.
Academic Article Large-scale association study between two coding LRP5 gene polymorphisms and bone phenotypes and fractures in men.
Academic Article Type I collagen alpha1 Sp1 polymorphism and the risk of cruciate ligament ruptures or shoulder dislocations.
Academic Article Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.
Academic Article Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
Academic Article Human metabolic individuality in biomedical and pharmaceutical research.
Academic Article Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.
Academic Article Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Academic Article Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.
Academic Article An atlas of genetic influences on osteoporosis in humans and mice.
Academic Article UCP1 expression-associated gene signatures of human epicardial adipose tissue.
Award or Honor Receipt Canada Research Chair in Disease Genomics and Epigenomics (Tier 2)
Grant Environmental Exposures, AHR Activation, and Placental Origins of Development
Grant Understanding etiology of metabolic diseases by integrative genomics and epigenomics approaches
Academic Article Capturing functional epigenomes for insight into metabolic diseases.
Academic Article Single-cell analysis of human adipose tissue identifies depot and disease specific cell types.
Grant Understanding Mechanisms Underlying Chronic Stress-Induced Asthma in Children by Population and Single-Cell Epigenomics Approaches
Academic Article Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range.
Academic Article Genomic answers for children: Dynamic analyses of >1000 pediatric rare disease genomes.

Search Criteria
  • Complex
  • diseases