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Selvarangan, Rangaraj

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Dr. Selvarangan is the Director of the Clinical Microbiology and Molecular Infectious Diseases Laboratory in Children’s Mercy Hospital accredited by College of American Pathologists. He has more than fifteen years of experience with directorship of high complexity clinical laboratory testing and research in the area of laboratory test evaluation and selection for implementation in routine clinical care. His research area encompasses advanced diagnostics for infectious diseases, epidemiology of infections in children, vaccine related studies, biomarker discovery and host response to infections and interventions to improve patient care and outcomes. His clinical research experience also includes federal funding and more than 100 clinical trials supported by In vitro diagnostic industry. His research team specializes in large volume prospective enrollment of children in clinical trials for infectious diseases in outpatient and inpatient settings. As the founding Principal Investigator of Kansas City-New Vaccine Surveillance Network (KC-NVSN) program since 2009, sponsored by Centers for Disease Control and Prevention, he has direct working knowledge on establishment and collaboration of multisite national networks.

One or more keywords matched the following items that are connected to Selvarangan, Rangaraj

Item Type	Name
Concept	Adenoviridae Infections
Concept	Adenovirus Infections, Human
Concept	Bacterial Infections
Concept	Bordetella Infections
Concept	Campylobacter Infections
Concept	Central Nervous System Infections
Concept	Chlamydia Infections
Concept	Clostridium Infections
Concept	Cross Infection
Concept	Cytomegalovirus Infections
Concept	Enterobacteriaceae Infections
Concept	Enterovirus Infections
Concept	Escherichia coli Infections
Concept	Haemophilus Infections
Concept	Klebsiella Infections
Concept	Mycobacterium Infections
Concept	Mycoplasma Infections
Concept	Picornaviridae Infections
Concept	Pneumococcal Infections
Concept	Pseudomonas Infections
Concept	Respiratory Tract Infections
Concept	Rotavirus Infections
Concept	Staphylococcal Infections
Concept	Staphylococcal Skin Infections
Concept	Streptococcal Infections
Concept	Urinary Tract Infections
Concept	Mycobacterium avium-intracellulare Infection
Concept	Immunocompromised Host
Concept	Gram-Positive Bacterial Infections
Concept	Infection Control
Concept	Caliciviridae Infections
Concept	Paramyxoviridae Infections
Concept	Coronavirus Infections
Concept	Respiratory Syncytial Virus Infections
Concept	Astroviridae Infections
Concept	Moraxellaceae Infections
Concept	Asymptomatic Infections
Academic Article	Genetic commonality of macrolide-resistant group A beta hemolytic streptococcus pharyngeal strains.
Academic Article	False-positive results of Campylobacter rapid antigen testing.
Academic Article	Mycoplasma edwardii peritonitis in a patient on maintenance peritoneal dialysis.
Academic Article	No evidence of vancomycin minimal inhibitory concentration creep or heteroresistance identified in pediatric Staphylococcus aureus blood isolates.
Academic Article	Prevalence of 3 sexually transmitted infections in a pediatric emergency department.
Academic Article	Enterovirus d68. A focused review and clinical highlights from the 2014 U.S. Outbreak.
Academic Article	Severe enterovirus 68 respiratory illness in children requiring intensive care management.
Academic Article	Severe respiratory illness associated with a nationwide outbreak of enterovirus D68 in the USA (2014): a descriptive epidemiological investigation.
Academic Article	Molecular Evolution and Intraclade Recombination of Enterovirus D68 during the 2014 Outbreak in the United States.
Academic Article	Reducing Overutilization of Testing for Clostridium difficile Infection in a Pediatric Hospital System: A Quality Improvement Initiative.
Academic Article	Clinical variables and Staphylococcus aureus virulence factors associated with venous thromboembolism in children.
Academic Article	Integrating a Rapid Diagnostic Test and Antimicrobial Stewardship: Optimizing Discharge Antibiotics in Skin and Soft Tissue Infections.
Academic Article	Clinical Course of Enterovirus D68 in Hospitalized Children.
Academic Article	Evaluating the Impact of Implementing a Clinical Practice Guideline for Febrile Infants With Positive Respiratory Syncytial Virus or Enterovirus Testing.
Academic Article	Outcome of children with rhinovirus detection prior to allogeneic hematopoietic cell transplant.
Academic Article	Dra/AfaE adhesin of uropathogenic Dr/Afa+ Escherichia coli mediates mortality in pregnant rats.
Academic Article	Disseminated nontuberculous mycobacterial infections in sickle cell anemia patients.
Academic Article	Treatment outcomes for nontuberculous mycobacterial cervicofacial lymphadenitis in children based on the type of surgical intervention.
Academic Article	Comparison of BD Directigen EZ RSV and Binax NOW RSV tests for rapid detection of respiratory syncytial virus from nasopharyngeal aspirates in a pediatric population.
Academic Article	Susceptibilities of Haemophilus influenzae, Streptococcus pneumoniae, including serotype 19A, and Moraxella catarrhalis paediatric isolates from 2005 to 2007 to commonly used antibiotics.
Academic Article	Human parechovirus 3 causing sepsis-like illness in children from midwestern United States.
Academic Article	Improving surveillance for pediatric Clostridium difficile infection: derivation and validation of an accurate case-finding tool.
Academic Article	Molecular epidemiology and clinical presentation of human adenovirus infections in Kansas City children.
Academic Article	Characterization of AfaE adhesins produced by extraintestinal and intestinal human Escherichia coli isolates: PCR assays for detection of Afa adhesins that do or do not recognize Dr blood group antigens.
Academic Article	Rapid receptor-clustering assay to detect uropathogenic and diarrheal Escherichia coli isolates bearing adhesins of the Dr family.
Academic Article	Interaction of Dr adhesin with collagen type IV is a critical step in Escherichia coli renal persistence.
Academic Article	Human parechovirus in respiratory specimens from children in Kansas City, Missouri.
Academic Article	Routine laboratory testing data for surveillance of rotavirus hospitalizations to evaluate the impact of vaccination.
Academic Article	Genotype prevalence and risk factors for severe clinical adenovirus infection, United States 2004-2006.
Academic Article	Role of nursing unit factors on performance of phlebotomy and subsequent blood culture contamination rates.
Academic Article	Innate Susceptibility to Norovirus Infections Influenced by FUT2 Genotype in a United States Pediatric Population.
Academic Article	Head-to-head comparison of the diagnostic accuracies of BD Veritor? System RSV and Quidel? Sofia? RSV FIA systems for respiratory syncytial virus (RSV) diagnosis.
Academic Article	BD Veritor System Respiratory Syncytial Virus Rapid Antigen Detection Test: Point-of-Care Results in Primary Care Pediatric Offices Compared With Reverse Transcriptase Polymerase Chain Reaction and Viral Culture Methods.
Academic Article	The human Parechoviruses: an overview.
Academic Article	Demographics and microbiology of otorrhea through patent tubes failing ototopical and/or oral antibiotic therapy.
Academic Article	Detection of toxigenic Clostridium difficile in pediatric stool samples: an evaluation of Quik Check Complete Antigen assay, BD GeneOhm Cdiff PCR, and ProGastro Cd PCR assays.
Academic Article	Clindamycin-susceptibility Rates of Methicillin-resistant Staphylococcus aureus Varies by Infection Type in Pediatric Patients.
Academic Article	A longitudinal case series description of meningitis due to Streptococcus gallolyticus subsp. pasteurianus in infants.
Academic Article	Rotavirus Strain Trends During the Postlicensure Vaccine Era: United States, 2008-2013.
Academic Article	Evaluation of xTAG Respiratory Viral Panel FAST and xTAG Human Parainfluenza Virus Analyte-Specific Reagents for detection of human parainfluenza viruses in respiratory specimens.
Academic Article	Utility of a focused vancomycin-resistant enterococci screening protocol to identify colonization in hospitalized children.
Academic Article	Optimization of a combined human parechovirus-enterovirus real-time reverse transcription-PCR assay and evaluation of a new parechovirus 3-specific assay for cerebrospinal fluid specimen testing.
Academic Article	Antibiotic Prophylaxis Is Associated with Subsequent Resistant Infections in Children with an Initial Extended-Spectrum-Cephalosporin-Resistant Enterobacteriaceae Infection.
Academic Article	The Molecular and Clinical Epidemiology of Extended-Spectrum Cephalosporin- and Carbapenem-Resistant Enterobacteriaceae at 4 US Pediatric Hospitals.
Academic Article	Severe Parechovirus 3 Infections in Young Infants-Kansas and Missouri, 2014.
Academic Article	Effectiveness of pentavalent and monovalent rotavirus vaccines in concurrent use among US children <5 years of age, 2009-2011.
Academic Article	Bordetella parapertussis bacteremia: two case reports.
Academic Article	Multicenter clinical performance evaluation of BD Veritor? system for rapid detection of respiratory syncytial virus.
Academic Article	Evaluation of RIDA?GENE norovirus GI/GII real time RT-PCR using stool specimens collected from children and adults with acute gastroenteritis.
Academic Article	Evaluation of the illumigene Mycoplasma Direct DNA Amplification Assay.
Academic Article	Severe respiratory illness associated with enterovirus D68 - Missouri and Illinois, 2014.
Academic Article	Evaluation of 3 analyte-specific reagents for detection of Bordetella pertussis and Bordetella parapertussis in clinical specimens.
Academic Article	Factors Associated With Rotavirus Vaccine Coverage.
Academic Article	Evidence for Household Transmission of Rotavirus in the United States, 2011-2016.
Academic Article	Emergence of Parechovirus A4 Central Nervous System Infections among Infants in Kansas City, Missouri, USA.
Academic Article	Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA1.
Academic Article	Epidemiologic Association Between FUT2 Secretor Status and Severe Rotavirus Gastroenteritis in Children in the United States.
Academic Article	Long-term Consistency in Rotavirus Vaccine Protection: RV5 and RV1 Vaccine Effectiveness in US Children, 2012-2013.
Academic Article	Use of Administrative Data for the Identificationof Laboratory-Confirmed Influenza Infection: The Validity ofInfluenza-Specific ICD-9 Codes.
Academic Article	Intestinal Carriage of Third-Generation Cephalosporin-Resistant and Extended-Spectrum ?-Lactamase-Producing Enterobacteriaceae in Healthy US Children.
Academic Article	Antifungal azoles itraconazole and posaconazole exhibit potent in vitro antiviral activity against clinical isolates of parechovirus A3 (Picornaviridae).
Academic Article	Multicenter Clinical Evaluation of the Alere i Respiratory Syncytial Virus Isothermal Nucleic Acid Amplification Assay.
Academic Article	Comparison of Six Sample-to-Answer Influenza A/B and Respiratory Syncytial Virus Nucleic Acid Amplification Assays Using Respiratory Specimens from Children.
Academic Article	Multicenter Clinical Evaluation of the Automated Aries Group A Strep PCR Assay from Throat Swabs.
Academic Article	Impact of multiplex molecular assay turn-around-time on antibiotic utilization and clinical management of hospitalized children with acute respiratory tract infections.
Academic Article	Seroepidemiology of Parechovirus A3 Neutralizing Antibodies, Australia, the Netherlands, and United States.
Academic Article	Development of experimental model of chronic pyelonephritis with Escherichia coli O75:K5:H-bearing Dr fimbriae: mutation in the dra region prevented tubulointerstitial nephritis.
Academic Article	Dr fimbriae operon of uropathogenic Escherichia coli mediate microtubule-dependent invasion to the HeLa epithelial cell line.
Academic Article	Laboratory diagnosis of Trypanosoma cruzi infection in a colony-raised pigtailed macaque.
Academic Article	Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018.
Academic Article	Evaluation of BacterioScan 216Dx in Comparison to Urinalysis as a Screening Tool for Diagnosis of Urinary Tract Infections in Children.
Academic Article	Comparative analysis of Four sample-to-answer influenza A/B and RSV nucleic acid amplification assays using adult respiratory specimens.
Academic Article	Infectious Causes of Acute Gastroenteritis in US Children Undergoing Allogeneic Hematopoietic Cell Transplant: A Longitudinal, Multicenter Study.
Academic Article	Association of Rotavirus Vaccination With Inpatient and Emergency Department Visits Among Children Seeking Care for Acute Gastroenteritis, 2010-2016.
Academic Article	Enterovirus D68 outbreak detection through a syndromic disease epidemiology network.
Academic Article	Evaluation of Genotypic Antiviral Resistance Testing as an Alternative to Phenotypic Testing in a Patient with DOCK8 Deficiency and Severe HSV-1 Disease.
Academic Article	Multicenter Clinical Evaluation of the Revogene Strep A Molecular Assay for Detection of Streptococcus pyogenes from Throat Swab Specimens.
Academic Article	Frequency of asymptomatic and symptomatic respiratory virus detection in pediatric hematopoietic cell transplant patients.
Academic Article	Detection of Clostridioides difficile by Real-time PCR in Young Children Does Not Predict Disease.
Academic Article	Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016.
Academic Article	Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children: Multicenter Surveillance, United States, January-March 2020.
Academic Article	Host Immune Response to Enterovirus and Parechovirus Systemic Infections in Children.
Academic Article	Positive Impact of Routine Testing for Enterovirus and Parechovirus on Length of Hospitalization and Antimicrobial Use among Inpatients =6 Months of Age.
Academic Article	Emergence of Parechovirus A3 as the Leading Cause of Central Nervous System Infection, Surpassing Any Single Enterovirus Type, in Children in Kansas City, Missouri, USA, from 2007 to 2016.
Academic Article	Childhood Outcomes Following Parechovirus Infections in a US Young Infant Cohort.
Academic Article	High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection.
Academic Article	Rotavirus Genotype Trends and Gastrointestinal Pathogen Detection in the United States, 2014-2016: Results From the New Vaccine Surveillance Network.
Grant	Enhanced Surveillance for New Vaccine Preventable Diseases
Academic Article	Global Trends in Norovirus Genotype Distribution among Children with Acute Gastroenteritis.
Academic Article	Real-time gastrointestinal infection surveillance through a cloud-based network of clinical laboratories.
Academic Article	Acute Respiratory Illnesses in Children in the SARS-CoV-2 Pandemic: Prospective Multicenter Study.
Academic Article	A multicenter evaluation of viral bloodstream detections in children presenting to the Emergency Department with suspected systemic infection.
Academic Article	Maternal parechovirus A (PeV-A) shedding, serostatus, and the risk of central nervous system PeV-A infections in infants.
Academic Article	The Impact of Prior Infection and Age on Antibody Persistence After Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine.
Academic Article	Clinical Influenza Testing Practices in Hospitalized Children at United States Medical Centers, 2015-2018.
Academic Article	Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-November 2018-2020.
Academic Article	Neutralizing Enterovirus D68 Antibodies in Children after 2014 Outbreak, Kansas City, Missouri, USA.
Academic Article	Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination.
Academic Article	Understanding Variation in Rotavirus Vaccine Effectiveness Estimates in the United States: The Role of Rotavirus Activity and Diagnostic Misclassification.
Academic Article	Vaccination After SARS-CoV-2 Infection Increased Antibody Avidity Against the Omicron Variant Compared to Vaccination Alone.
Academic Article	A multi-center study to determine genetic variations in the fusion gene of respiratory syncytial virus (RSV) from children <2 years of age in the U.S.
Academic Article	Differences in pediatric SARS-CoV-2 symptomology and Co-infection rates among COVID-19 Pandemic waves.
Academic Article	Clinical Presentation and Severity of Adenovirus Detection Alone vs Adenovirus Co-detection With Other Respiratory Viruses in US Children With Acute Respiratory Illness from 2016 to 2018.
Academic Article	Cepheid Xpert Xpress Flu/RSV evaluation performed by minimally trained non-laboratory operators in a CLIA-waived environment.
Academic Article	Rotavirus Strain Trends in United States, 2009-2016: Results from the National Rotavirus Strain Surveillance System (NRSSS).
Academic Article	Comparative analysis of three multiplex platforms for the detection of respiratory viral pathogens.
Academic Article	Respiratory Virus Surveillance Among Children with Acute Respiratory Illnesses - New Vaccine Surveillance Network, United States, 2016-2021.
Academic Article	Disruption of seasonal enterovirus and parechovirus detections in the CSF and plasma of children during the COVID-19 pandemic.
Academic Article	Circulation of Rhinoviruses and/or Enteroviruses in Pediatric Patients With Acute Respiratory Illness Before and During the COVID-19 Pandemic in the US.
Academic Article	Comparative in vitro antipseudomonal activity of ceftolozane/tazobactam against Pseudomonas aeruginosa isolates from children with cystic fibrosis.
Academic Article	Multicenter Evaluation of the DiaSorin Molecular Simplexa Congenital CMV Direct PCR Test on Neonatal Saliva and Urine Specimens.
Academic Article	A Comparison of Pathogen Detection and Risk Factors among Symptomatic Children with Gastroenteritis Compared with Asymptomatic Children in the Post-rotavirus Vaccine Era.
Academic Article	Prevalence and clinical presentation of EV-D68 infections in Kansas City children during the 2022 season.
Academic Article	Multi-center clinical evaluation of the Panther Fusion SARS-CoV-2/Flu A/B/RSV assay in nasopharyngeal swab specimens from symptomatic individuals.
Academic Article	Respiratory Syncytial Virus-Associated Hospitalizations Among Children <5 Years Old: 2016 to 2020.
Academic Article	Seasonality, Clinical Characteristics, and Outcomes of Respiratory Syncytial Virus Disease by Subtype Among Children Aged <5 Years: New Vaccine Surveillance Network, United States, 2016-2020.
Academic Article	Notes from the Field: Reemergence of Mycoplasma pneumoniae Infections in Children and Adolescents After the COVID-19 Pandemic, United States, 2018-2024.
Academic Article	Early Estimate of Nirsevimab Effectiveness for Prevention of Respiratory Syncytial Virus-Associated Hospitalization Among Infants Entering Their First Respiratory Syncytial Virus Season - New Vaccine Surveillance Network, October 2023-February 2024.
Academic Article	Medical Costs of Respiratory Syncytial Virus-Associated Hospitalizations and Emergency Department Visits in Children Aged Younger Than 5?Years: Observational Findings from the New Vaccine Surveillance Network, 2016-2019.
Academic Article	Diagnosis, management, and outcomes of parechovirus infections in infants: an overview.
Academic Article	Prevalence and Genetic Diversity of Adenovirus 40/41, Astrovirus, and Sapovirus in Children With Acute Gastroenteritis in Kansas City, 2011-2016.
Academic Article	Respiratory Syncytial Virus-Associated Hospitalizations in Children <5 Years: 2016-2022.
Academic Article	Pneumococcal Colonization in Children With Persistent Asthma: A Retrospective Cohort.
Academic Article	School knowledge of infectious diseases in schools: conducting surveillance and on-demand, symptomatic respiratory viral testing in a large pre-kindergarten-12th grade school district.
Academic Article	Influenza C virus in U.S. children with acute respiratory infection 2016-2019.
Academic Article	Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022.
Academic Article	Prevalence of SARS-CoV-2 in Children Identified by Preprocedural Testing at 5 US Children's Hospital Systems.
Academic Article	Respiratory Syncytial Virus Disease Burden and Nirsevimab Effectiveness in Young Children From 2023-2024.
Academic Article	Antimicrobial Susceptibility Trends in E. coli Causing Pediatric Urinary Tract Infections in the United States.

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Infections
immunocompromised hosts