D004742Chemicals & DrugsG02.111.570.080.689.330G05.360.080.689.330G05.360.340.024.340.137.750.2497180.986187Enhancer Elements, Geneticcmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonMD, PhDTomiPastinenTomi Pastinen0.000000000000000.00000000000000113Pastinen, TomiDirector, Center for Pediatric Genomic Medicine PhD, MScWarrenCheungWarren Cheung0.000000000000000.00000000000000119Cheung, Warren0000-0003-0267-7464Bioinformatics Manager2Associate Professor1Professor28903037Li N, Johnson DC, Weinhold N, Kimber S, Dobbins SE, Mitchell JS, Kinnersley B, Sud A, Law PJ, Orlando G, Scales M, Wardell CP, F?rsti A, Hoang PH, Went M, Holroyd A, Hariri F, Pastinen T, Meissner T, Goldschmidt H, Hemminki K, Morgan GJ, Kaiser M, Houlston RSCell reportsLi N, Johnson DC, Weinhold N, Kimber S, Dobbins SE, Mitchell JS, Kinnersley B, Sud A, Law PJ, Orlando G, Scales M, Wardell CP, F?rsti A, Hoang PH, Went M, Holroyd A, Hariri F, Pastinen T, Meissner T, Goldschmidt H, Hemminki K, Morgan GJ, Kaiser M, Houlston RS. Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism. Cell Rep. 2017 Sep 12; 20(11):2556-2564.Cell Rep2017-09-12T00:00:002017Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism.29358650Mayran A, Khetchoumian K, Hariri F, Pastinen T, Gauthier Y, Balsalobre A, Drouin JNature geneticsMayran A, Khetchoumian K, Hariri F, Pastinen T, Gauthier Y, Balsalobre A, Drouin J. Pioneer factor Pax7 deploys a stable enhancer repertoire for specification of cell fate. Nat Genet. 2018 02; 50(2):259-269.Nat Genet2018-01-22T00:00:002018Pioneer factor Pax7 deploys a stable enhancer repertoire for specification of cell fate.28973438Younger ST, Rinn JLNucleic acids researchYounger ST, Rinn JL. p53 regulates enhancer accessibility and activity in response to DNA damage. Nucleic Acids Res. 2017 Sep 29; 45(17):9889-9900.Nucleic Acids Res2017-09-29T00:00:002017p53 regulates enhancer accessibility and activity in response to DNA damage.PhDScottYoungerScott T. Younger0.000000000000000.00000000000000137Younger, Scott0000-0002-6237-445XDirector of Disease Gene Engineering, Center for Pediatric Genomic MedicinePhDElinGrundbergElin Grundberg0.000000000000000.00000000000000138Grundberg, Elin0000-0001-5415-7896Roberta D. Harding & William F. Bradley Jr. Endowed Chair in Genomic Research PediatricsResearchClinicalChildren's Mercy Kansas City33863903Watt S, Vasquez L, Walter K, Mann AL, Kundu K, Chen L, Sims Y, Ecker S, Burden F, Farrow S, Farr B, Iotchkova V, Elding H, Mead D, Tardaguila M, Ponstingl H, Richardson D, Datta A, Flicek P, Clarke L, Downes K, Pastinen T, Fraser P, Frontini M, Javierre BM, Spivakov M, Soranzo NNature communicationsWatt S, Vasquez L, Walter K, Mann AL, Kundu K, Chen L, Sims Y, Ecker S, Burden F, Farrow S, Farr B, Iotchkova V, Elding H, Mead D, Tardaguila M, Ponstingl H, Richardson D, Datta A, Flicek P, Clarke L, Downes K, Pastinen T, Fraser P, Frontini M, Javierre BM, Spivakov M, Soranzo N. Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease. Nat Commun. 2021 04 16; 12(1):2298.Nat Commun2021-04-16T00:00:002021Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.true1Bioinformatics ManagerBioinformatics ManagerGenomic Medicine CenterPhDBrookeFridleyBrooke Fridley0.000000000000000.00000000000000222Fridley, BrookeDirector, Biostatistics and Epidemiology Core35234924Liu X, Zhao B, Shaw TI, Fridley BL, Duckett DR, Tan AC, Teng MNucleic acids researchLiu X, Zhao B, Shaw TI, Fridley BL, Duckett DR, Tan AC, Teng M. Summarizing internal dynamics boosts differential analysis and functional interpretation of super enhancers. Nucleic Acids Res. 2022 04 08; 50(6):3115-3127.Nucleic Acids Res2022-04-08T00:00:002022Summarizing internal dynamics boosts differential analysis and functional interpretation of super enhancers.true1Director, Biostatistics and Epidemiology CoreDirector, Biostatistics and Epidemiology Coretrue1Director of Disease Gene Engineering, Center for Pediatric Genomic MedicineDirector of Disease Gene Engineering, Center for Pediatric Genomic Medicinetrue1Director, Center for Pediatric Genomic Medicine Director, Center for Pediatric Genomic Medicine true1Roberta D. Harding & William F. Bradley Jr. Endowed Chair in Genomic Research Roberta D. Harding & William F. Bradley Jr. Endowed Chair in Genomic Research 1.210960.04096327research area of0.8727840.020535317subject area for