D001711PhysiologyG03.495.244G03.787.225G07.690.725.2255490.98009Biotransformationcmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson27457783Goldman JL, Koen YM, Rogers SA, Li K, Leeder JS, Hanzlik RPDrug metabolism and disposition: the biological fate of chemicalsGoldman JL, Koen YM, Rogers SA, Li K, Leeder JS, Hanzlik RP. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes. Drug Metab Dispos. 2016 10; 44(10):1603-7.Drug Metab Dispos2016-07-25T00:00:002016Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes.MDJenniferGoldmanJennifer L. Goldman87Goldman, JenniferDirector, Drug Safety Service3Assistant Professor1Professor23Director30515762Yang JJ, Whirl-Carrillo M, Scott SA, Turner AJ, Schwab M, Tanaka Y, Suarez-Kurtz G, Schaeffeler E, Klein TE, Miller NA, Gaedigk AClinical pharmacology and therapeuticsYang JJ, Whirl-Carrillo M, Scott SA, Turner AJ, Schwab M, Tanaka Y, Suarez-Kurtz G, Schaeffeler E, Klein TE, Miller NA, Gaedigk A. Pharmacogene Variation Consortium Gene Introduction: NUDT15. Clin Pharmacol Ther. 2019 05; 105(5):1091-1094.Clin Pharmacol Ther2018-12-04T00:00:002018Pharmacogene Variation Consortium Gene Introduction: NUDT15.31355458Gaedigk AClinical pharmacology and therapeuticsGaedigk A. Pharmacogenetics: Chasing Perfection. Clin Pharmacol Ther. 2019 08; 106(2):265-270.Clin Pharmacol Ther2019-08-01T00:00:002019Pharmacogenetics: Chasing Perfection.PediatricsResearchClinicalPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteChildren's Mercy Kansas CityPhDPaulTorenPaul C. Toren0.000000000000000.00000000000000164Toren, PaulDirector, Analytical Chemistry Core32847865Chapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JSDrug metabolism and disposition: the biological fate of chemicalsChapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JS. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites. Drug Metab Dispos. 2020 11; 48(11):1113-1120.Drug Metab Dispos2020-08-26T00:00:002020The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites.PhD, APRNStephaniStancilStephani L. Stancil0.000000000000000.00000000000000199Stancil, Stephani0000-0001-7308-3132Clinician Scientist, Adolescent Medicine34728519Stancil SL, Nolte W, Pearce RE, Staggs VS, Leeder JSDrug metabolism and disposition: the biological fate of chemicalsStancil SL, Nolte W, Pearce RE, Staggs VS, Leeder JS. The Impact of Age and Genetics on Naltrexone Biotransformation. Drug Metab Dispos. 2022 02; 50(2):168-173.Drug Metab Dispos2021-11-02T00:00:002021The Impact of Age and Genetics on Naltrexone Biotransformation.true1Clinician Scientist, Adolescent MedicineClinician Scientist, Adolescent Medicinetrue1Director, Analytical Chemistry CoreDirector, Analytical Chemistry Core1.997420.08694785research area of0.7049960.03879444subject area fortrue1Director, Drug Safety ServiceDirector, Drug Safety Servicetrue1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research Institute