D001665Chemicals & DrugsG02.111.570.12016280.99228Binding Sitescmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson28960269Burgess KS, Ipe J, Swart M, Metzger IF, Lu J, Gufford BT, Thong N, Desta Z, Gaedigk R, Pearce RE, Gaedigk A, Liu Y, Skaar TCClinical pharmacology and therapeuticsBurgess KS, Ipe J, Swart M, Metzger IF, Lu J, Gufford BT, Thong N, Desta Z, Gaedigk R, Pearce RE, Gaedigk A, Liu Y, Skaar TC. Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs. Clin Pharmacol Ther. 2018 07; 104(1):130-138.Clin Pharmacol Ther2017-10-25T00:00:002017Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs.3Assistant Professor1Professor30168593Shokoohi F, Stephens DA, Bourque G, Pastinen T, Greenwood CMT, Labbe ABiometricsShokoohi F, Stephens DA, Bourque G, Pastinen T, Greenwood CMT, Labbe A. A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data. Biometrics. 2019 03; 75(1):210-221.Biometrics2018-10-09T00:00:002018A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data.28973438Younger ST, Rinn JLNucleic acids researchYounger ST, Rinn JL. p53 regulates enhancer accessibility and activity in response to DNA damage. Nucleic Acids Res. 2017 Sep 29; 45(17):9889-9900.Nucleic Acids Res2017-09-29T00:00:002017p53 regulates enhancer accessibility and activity in response to DNA damage.PhDScottYoungerScott T. Younger0.000000000000000.00000000000000137Younger, Scott0000-0002-6237-445XDirector of Disease Gene Engineering, Center for Pediatric Genomic MedicinePhDToddBradleyTodd Bradley0.000000000000000.00000000000000145Bradley, ToddDirector of Immunogenomics, Center for Pediatric Genomic MedicinePediatricsResearchClinicalPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstitutePhDTaejuParkTaeju Park0.000000000000000.0000000000000041Park, Taeju0000-0003-3897-3994Research Faculty PhDChildren's Mercy Kansas City32005150Borys SM, Younger STBMC genomicsBorys SM, Younger ST. Identification of functional regulatory elements in the human genome using pooled CRISPR screens. BMC Genomics. 2020 Jan 31; 21(1):107.BMC Genomics2020-01-31T00:00:002020Identification of functional regulatory elements in the human genome using pooled CRISPR screens.25972460Ke X, McKnight RA, Gracey Maniar LE, Sun Y, Callaway CW, Majnik A, Lane RH, Cohen SSAmerican journal of physiology. Regulatory, integrative and comparative physiologyKe X, McKnight RA, Gracey Maniar LE, Sun Y, Callaway CW, Majnik A, Lane RH, Cohen SS. IUGR increases chromatin-remodeling factor Brg1 expression and binding to GR exon 1.7 promoter in newborn male rat hippocampus. Am J Physiol Regul Integr Comp Physiol. 2015 Jul 15; 309(2):R119-27.Am J Physiol Regul Integr Comp Physiol2015-05-13T00:00:002015IUGR increases chromatin-remodeling factor Brg1 expression and binding to GR exon 1.7 promoter in newborn male rat hippocampus.0.44610.0041829716research area of0.1875330.0084310353subject area fortrue1Research Faculty PhDResearch Faculty PhDtrue1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Director of Disease Gene Engineering, Center for Pediatric Genomic MedicineDirector of Disease Gene Engineering, Center for Pediatric Genomic Medicinetrue1Director of Immunogenomics, Center for Pediatric Genomic MedicineDirector of Immunogenomics, Center for Pediatric Genomic Medicinetrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research Institute