Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness.
Li C, Wu B, Li Y, Liu Y, Wang J, Xie J, Xu X, Tian X, Ye Z, Guan J, Chen J, Xie S, Zhang B, Cai B, Wang Q, Yu H, Lan T, Man CH, Kang X, Qian P, Perry JM, He A, Jiang L, Zhao M. Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness. Blood. 2022 10 13; 140(15):1686-1701.