The objective of this study is to advance translational science by examining factors influencing youth research advisory board (YRAB) implementation and sustainability within clinical and translational science institutes (CTSIs). To that end, we will 1) describe current use of YRABs within CTSIs through a national survey and individual interviews of CTSI leaders and YRAB members and 2) assess contexts, processes, and immediate outcomes during YRAB implementation at Children's Mercy.