33539569Downes KJ, Goldman JLClinical pharmacology and therapeuticsAnti-Infective Agents; Drug MonitoringArea Under Curve; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Humans; Microbiological TechniquesDownes KJ, Goldman JL. Too Much of a Good Thing: Defining Antimicrobial Therapeutic Targets to Minimize Toxicity. Clin Pharmacol Ther. 2021 04; 109(4):905-917.Clin Pharmacol Ther2021-02-27T00:00:002021Too Much of a Good Thing: Defining Antimicrobial Therapeutic Targets to Minimize Toxicity.cmhprofilesont:personsuffixperson suffixprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD008828Procedures450.997927Microbiological TechniquesD016903Procedures10190.983245Drug MonitoringD019540Concepts & Ideas13340.990747Area Under CurveMDJenniferGoldmanJennifer L. Goldman87Goldman, JenniferDirector, Drug Safety ServiceD064420Disorders16390.938676Drug-Related Side Effects and Adverse ReactionsPediatricsClinicalChildren's Mercy Kansas CityD000890Chemicals & Drugs8210.9718Anti-Infective AgentsAuthorship 879220.8082160.8082161authors10.257has subject areatrue1Director, Drug Safety ServiceDirector, Drug Safety ServiceD004305Concepts & Ideas38950.95931Dose-Response Relationship, DrugD006801Living Beings12067970.397999Humans