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Institution

Statin Optimization in Pediatrics


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Collapse Overview 
Collapse abstract
Major Goals: 1) Determine the role of gastric acid on the formation of 3a-PVA and the functional consequences of 3a-PVA on PVA transport. 2) Develop and validate a PBPK model of pravastatin in children and adolescents from planned and existing biotransformation and pharmacogenomics studies to optimize statin therapy in children.
Collapse sponsor award id
KL2TR002367

Collapse Time 
Collapse start date
2017-09-01
Collapse end date
2020-06-30