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The effect of a high-calorie diet on bone growth is mediated by the insulin receptor.
Wu S, Zhang Y, De Luca F. The effect of a high-calorie diet on bone growth is mediated by the insulin receptor. Bone. 2019 05; 122:166-175.
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PubMed
subject areas
3-Hydroxybutyric Acid
Animals
Apoptosis
Bone Development
Cell Differentiation
Cell Proliferation
Cells, Cultured
Chondrocytes
Diet, High-Fat
Gene Deletion
Growth Plate
Hormones
Insulin
Insulin-Like Growth Factor I
Leptin
Metabolome
Mice, Knockout
Organ Specificity
Phosphorylation
Proto-Oncogene Proteins c-akt
Receptor, Insulin
Signal Transduction
Tibia
Weight Gain
The effect of a high-calorie diet on bone growth is mediated by the insulin receptor.