MD, PhD, FCAPMD, PhD, FCAPMidhatFarooqiMidhat Farooqi0.000000000000000.00000000000000161Farooqi, Midhat8168551958EpigeneticsImmunotherapyPediatric CancerGenomicsPathology, ClinicalPathology, Diagnostic Molecular0000-0002-5238-13498162343059Director, Molecular Oncology, Center for Pediatric Genomic MedicineAs a molecular pathologist, Dr. Farooqi interprets clinical genetic testing results for both pediatric and adult patients in the setting of inherited disease and oncology, including whole exome sequencing and tumor somatic profiling. His clinical interests involve the development of new clinical diagnostic tests, especially for pediatric oncology. His research interests include epigenetic profiling and single cell sequencing of pediatric liquid and solid tumors. Dr. Farooqi works closely with Dr. Erin Guest and other researchers at the Genomic Medicine Center (GMC). The scientists in the GMC have extensive experience in all aspects of sequencing and have supported two clinical trials studying leukemia in children and infants—T2016-003 and AALL0631—by performing and analyzing whole genome, whole exome, bulk RNA, whole genome bisulfite, single cell, and long read sequencing of patient samples in collaboration with Johns Hopkins University and the Children's Hospital of Philadelphia. The research team will be performing similar work for two current trials: AALL15P1 (studying infant leukemia) and NCT02789228 (studying multi-antigen specific lymphocytes for the treatment of pediatric solid tumors); Dr. Farooqi is the Principal Investigator for the sequencing project supporting NCT02789228. He is also the Principal Investigator for a grant from the National Cancer Institute centered around sequence data sharing from pediatric tumors in support of the nationwide Childhood Cancer Data Initiative. Dr. Farooqi looks forward to additional collaborative sequencing projects, especially in the areas of pediatric oncology and cancer immunotherapy.cmhprofilesont:personsuffixperson suffixprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:trainingAtOrganizationeducational organizationprns:trainingLocationtraining locationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifierbibo:suffixNamename suffixAddressvivo:address1address line 1vivo:address2address line 2vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipCertificationvivo:degreeEarneddegree earnedDepartmentDivisionvivo:educationalTrainingeducation and trainingEducational Trainingvivo:faxNumberfaxvivo:freetextKeywordkeywordsGrantvivo:hasCredentialcredentialsvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation ResourceIssued Credentialvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:orcidIdORCID idvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:researchOverviewresearch overviewRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD017422Procedures301150.947191Sequence Analysis, DNAMD, PhDTomiPastinenTomi Pastinen0.000000000000000.00000000000000113Pastinen, TomiDirector, Center for Pediatric Genomic Medicine MDBradleyWaradyBradley A. Warady0.000000000000000.0000000000000063Warady, BradleyDirector, Division of Pediatric Nephrology D020022Physiology382240.885426Genetic Predisposition to Disease3Assistant Professor2Associate Professor1ProfessorPhD, CGCEmilyFarrowEmily G. Farrow0.000000000000000.00000000000000124Farrow, EmilyDirector of Lab OperationsSurgeryMDShawnSt PeterShawn D St Peter0.000000000000000.00000000000000131St Peter, ShawnMedical Chairman D059014Procedures281000.923739High-Throughput Nucleotide Sequencing30551569Ahmed AA, Vundamati DS, Farooqi MS, Guest EHigh-throughputAhmed AA, Vundamati DS, Farooqi MS, Guest E. Precision Medicine in Pediatric Cancer: Current Applications and Future Prospects. High Throughput. 2018 Dec 13; 7(4).High Throughput2018-12-13T00:00:002018Precision Medicine in Pediatric Cancer: Current Applications and Future Prospects.MDErinGuestErin M. Guest0.000000000000000.00000000000000150Guest, Erin0000-0003-2482-5608Hematology/Oncology PediatricianPathology and Laboratory MedicinePediatricsMedical SchoolResearchClinicalUniversity of Kansas Medical CenterUniversity of Missouri-Kansas CityPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryChildren's Mercy Kansas City2401 Gillham RdKansas City MO 64108Kansas City64108MOAuthorship 63324Authorship 63612Authorship 64534Authorship 65001Authorship 65441Authorship 65782Authorship 65801Authorship 662817Authorship 66648Authorship 66885Authorship 67333Authorship 67345Authorship 67757Authorship 67912Authorship 67994Authorship 68013Authorship 68968Authorship 69443027155050Davies KD, Farooqi MS, Gruidl M, Hill CE, Woolworth-Hirschhorn J, Jones H, Jones KL, Magliocco A, Mitui M, O'Neill PH, O'Rourke R, Patel NM, Qin D, Ramos E, Rossi MR, Schneider TM, Smith GH, Zhang L, Park JY, Aisner DLThe Journal of molecular diagnostics : JMDDavies KD, Farooqi MS, Gruidl M, Hill CE, Woolworth-Hirschhorn J, Jones H, Jones KL, Magliocco A, Mitui M, O'Neill PH, O'Rourke R, Patel NM, Qin D, Ramos E, Rossi MR, Schneider TM, Smith GH, Zhang L, Park JY, Aisner DL. Multi-Institutional FASTQ File Exchange as a Means of Proficiency Testing for Next-Generation Sequencing Bioinformatics and Variant Interpretation. J Mol Diagn. 2016 07; 18(4):572-9.J Mol Diagn2016-05-04T00:00:002016Multi-Institutional FASTQ File Exchange as a Means of Proficiency Testing for Next-Generation Sequencing Bioinformatics and Variant Interpretation.27217445Farooqi MS, Mitui M, Londin ER, Park JYClinical chemistryFarooqi MS, Mitui M, Londin ER, Park JY. High Concentration Capture Probes Enhance Massively Parallel Sequencing Assays. Clin Chem. 2016 07; 62(7):1032-4.Clin Chem2016-05-23T00:00:002016High Concentration Capture Probes Enhance Massively Parallel Sequencing Assays.30553474Sussman RT, Shaffer S, Azzato EM, DeSloover D, Farooqi MS, Meyer A, Lieberman DB, Bigdeli A, Paolillo C, Ganapathy K, Sukhadia S, Rosenbaum JN, Daber RD, Morrissette JJDCancer geneticsSussman RT, Shaffer S, Azzato EM, DeSloover D, Farooqi MS, Meyer A, Lieberman DB, Bigdeli A, Paolillo C, Ganapathy K, Sukhadia S, Rosenbaum JN, Daber RD, Morrissette JJD. Validation of a next-generation sequencing oncology panel optimized for low input DNA. Cancer Genet. 2018 12; 228-229:55-63.Cancer Genet2018-09-19T00:00:002018Validation of a next-generation sequencing oncology panel optimized for low input DNA.22927400Owen JL, Zhang Y, Bae SH, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MSProceedings of the National Academy of Sciences of the United States of AmericaOwen JL, Zhang Y, Bae SH, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MS. Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16184-9.Proc Natl Acad Sci U S A2012-08-27T00:00:002012Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase.28459186Goldberg DS, Abt PL, Blumberg EA, Van Deerlin VM, Levine M, Reddy KR, Bloom RD, Nazarian SM, Sawinski D, Porrett P, Naji A, Hasz R, Suplee L, Trofe-Clark J, Sicilia A, McCauley M, Farooqi M, Gentile C, Smith J, Reese PPThe New England journal of medicineGoldberg DS, Abt PL, Blumberg EA, Van Deerlin VM, Levine M, Reddy KR, Bloom RD, Nazarian SM, Sawinski D, Porrett P, Naji A, Hasz R, Suplee L, Trofe-Clark J, Sicilia A, McCauley M, Farooqi M, Gentile C, Smith J, Reese PP. Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients. N Engl J Med. 2017 06 15; 376(24):2394-2395.N Engl J Med2017-04-30T00:00:002017Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients.31451289Repnikova E, Roberts J, Mc Dermott S, Farooqi MS, Iqbal NT, Silvey M, Nolen J, Taboada E, Li WPathology, research and practiceRepnikova E, Roberts J, Mc Dermott S, Farooqi MS, Iqbal NT, Silvey M, Nolen J, Taboada E, Li W. Clinical and molecular characterization of novel deletions causing epsilon gamma delta beta thalassemia: Report of two cases. Pathol Res Pract. 2019 Oct; 215(10):152578.Pathol Res Pract2019-08-05T00:00:002019Clinical and molecular characterization of novel deletions causing epsilon gamma delta beta thalassemia: Report of two cases.31306780Ahmed IA, Farooqi MS, Vander Lugt MT, Boklan J, Rose M, Friehling ED, Triplett B, Lieuw K, Saldana BD, Smith CM, Schwartz JR, Goyal RKBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow TransplantationAhmed IA, Farooqi MS, Vander Lugt MT, Boklan J, Rose M, Friehling ED, Triplett B, Lieuw K, Saldana BD, Smith CM, Schwartz JR, Goyal RK. Outcomes of Hematopoietic Cell Transplantation in Patients with Germline SAMD9/SAMD9L Mutations. Biol Blood Marrow Transplant. 2019 11; 25(11):2186-2196.Biol Blood Marrow Transplant2019-07-12T00:00:002019Outcomes of Hematopoietic Cell Transplantation in Patients with Germline SAMD9/SAMD9L Mutations.24961613Farooqi MS, Lai Y, Lancaster E, Schmitt SE, Sachais BSJournal of clinical apheresisFarooqi MS, Lai Y, Lancaster E, Schmitt SE, Sachais BS. Therapeutic plasma exchange and immunosuppressive therapy in a patient with anti-GAD antibody-related epilepsy: quantification of the antibody response. J Clin Apher. 2015 Feb; 30(1):8-14.J Clin Apher2014-06-25T00:00:002014Therapeutic plasma exchange and immunosuppressive therapy in a patient with anti-GAD antibody-related epilepsy: quantification of the antibody response.31076445Li W, Cooley LD, August KJ, Richardson AI, Shao L, Ahmed AA, Farooqi MS, Zwick DLBloodLi W, Cooley LD, August KJ, Richardson AI, Shao L, Ahmed AA, Farooqi MS, Zwick DL. Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL. Blood. 2019 07 18; 134(3):324-329.Blood2019-05-10T00:00:002019Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL.26220582Farooqi MS, Hashim IAClinical chemistryFarooqi MS, Hashim IA. A woman with primary biliary cirrhosis and hyponatremia. Clin Chem. 2015 Aug; 61(8):1028-31.Clin Chem2015-08-01T00:00:002015A woman with primary biliary cirrhosis and hyponatremia.29220079Gentile C, Van Deerlin VM, Goldberg DS, Reese PP, Hasz RD, Abt P, Blumberg E, Farooqi MSClinical transplantationGentile C, Van Deerlin VM, Goldberg DS, Reese PP, Hasz RD, Abt P, Blumberg E, Farooqi MS. Hepatitis C virus genotyping of organ donor samples to aid in transplantation of HCV-positive organs. Clin Transplant. 2018 02; 32(2).Clin Transplant2017-12-21T00:00:002017Hepatitis C virus genotyping of organ donor samples to aid in transplantation of HCV-positive organs.18552832Schneider JW, Gao Z, Li S, Farooqi M, Tang TS, Bezprozvanny I, Frantz DE, Hsieh JNature chemical biologySchneider JW, Gao Z, Li S, Farooqi M, Tang TS, Bezprozvanny I, Frantz DE, Hsieh J. Small-molecule activation of neuronal cell fate. Nat Chem Biol. 2008 Jul; 4(7):408-10.Nat Chem Biol2008-06-15T00:00:002008Small-molecule activation of neuronal cell fate.31550935Ahmed AA, Vundamati D, Farooqi M, Repnikova E, Zinkus T, Hetherington M, Paulson LEar, nose, & throat journalAhmed AA, Vundamati D, Farooqi M, Repnikova E, Zinkus T, Hetherington M, Paulson L. Next-Generation Sequencing in the Diagnosis of Rare Pediatric Sinonasal Tumors. Ear Nose Throat J. 2021 Jun; 100(5):NP263-NP268.Ear Nose Throat J2019-09-24T00:00:002019Next-Generation Sequencing in the Diagnosis of Rare Pediatric Sinonasal Tumors.31825089Porath B, Farooki S, Gener M, Amudhavalli SM, Grote L, Cooley LD, Ginn K, Farooqi MSClinical geneticsPorath B, Farooki S, Gener M, Amudhavalli SM, Grote L, Cooley LD, Ginn K, Farooqi MS. Occurrence and characterization of medulloblastoma in a patient with Curry-Jones syndrome. Clin Genet. 2020 04; 97(4):670-671.Clin Genet2019-12-11T00:00:002019Occurrence and characterization of medulloblastoma in a patient with Curry-Jones syndrome.31969338Burke MJ, Kostadinov R, Sposto R, Gore L, Kelley SM, Rabik C, Trepel JB, Lee MJ, Yuno A, Lee S, Bhojwani D, Jeha S, Chang BH, Sulis ML, Hermiston ML, Gaynon P, Huynh V, Verma A, Gardner R, Heym KM, Dennis RM, Ziegler DS, Laetsch TW, Oesterheld JE, Dubois SG, Pollard JA, Glade-Bender J, Cooper TM, Kaplan JA, Farooqi MS, Yoo B, Guest E, Wayne AS, Brown PAClinical cancer research : an official journal of the American Association for Cancer ResearchBurke MJ, Kostadinov R, Sposto R, Gore L, Kelley SM, Rabik C, Trepel JB, Lee MJ, Yuno A, Lee S, Bhojwani D, Jeha S, Chang BH, Sulis ML, Hermiston ML, Gaynon P, Huynh V, Verma A, Gardner R, Heym KM, Dennis RM, Ziegler DS, Laetsch TW, Oesterheld JE, Dubois SG, Pollard JA, Glade-Bender J, Cooper TM, Kaplan JA, Farooqi MS, Yoo B, Guest E, Wayne AS, Brown PA. Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study. Clin Cancer Res. 2020 05 15; 26(10):2297-2307.Clin Cancer Res2020-01-22T00:00:002020Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study.20090767Evers BM, Farooqi MS, Shelton JM, Richardson JA, Goldstein JL, Brown MS, Liang GThe Journal of investigative dermatologyEvers BM, Farooqi MS, Shelton JM, Richardson JA, Goldstein JL, Brown MS, Liang G. Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin. J Invest Dermatol. 2010 May; 130(5):1237-48.J Invest Dermatol2010-01-21T00:00:002010Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.29636372Rea B, Haun P, Emerson R, Vignali M, Farooqi M, Samimi S, Elenitsas R, Kirsch I, Bagg AJournal of clinical pathologyRea B, Haun P, Emerson R, Vignali M, Farooqi M, Samimi S, Elenitsas R, Kirsch I, Bagg A. Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma. J Clin Pathol. 2018 Sep; 71(9):814-820.J Clin Pathol2018-04-10T00:00:002018Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma.1134selected publications2.129270.0193304200research areas0.5270630.05110178coauthor of39.23284.1501260similar toMD, FACS, FAAPRichardHendricksonRichard J Hendrickson0.000000000000000.00000000000000165Hendrickson, RichardSurgical Director, Transplantation 2012University of Texas Southwestern Medical CenterDallas, TXUniversity of Texas Southwestern Medical Center, Molecular GeneticsMD, PhDMolecular Genetics2013Hospital of the University of PennsylvaniaPhiladelphia, PAHospital of the University of Pennsylvania, Anatomic & Clinical PathologyResidencyAnatomic & Clinical Pathology2015University of Texas Southwestern Medical CenterDallas, TXUniversity of Texas Southwestern Medical Center, Clinical PathologyResidencyClinical Pathology2016Hospital of the University of PennsylvaniaPhiladelphia, PAHospital of the University of Pennsylvania, Molecular Genetic PathologyFellowshipMolecular Genetic PathologyMolecular Genetic Pathology, American Board of Pathology & American Board of Medical Genetics & GenomicsClinical Pathology, American Board of PathologyPrincipal Investigator2024-06-30Braden’s Hope For Childhood CancerMidhat Farooqi2019-12-01Targeting Solid Tumors with Multi-antigen Specific T cells by Identifying the Genetic and Epigenetic Determinants of Therapeutic ResponsePhD, MScDithiBanerjeeDithi Banerjee0.000000000000000.00000000000000170Banerjee, DithiResearch Scientist PhDMDKevinGinnKevin F. Ginn0.000000000000000.00000000000000176Ginn, KevinNeuro-Oncologist and Director, Pediatric Brain Tumor ProgramPhD, MVScNeenaKanwarNeena Kanwar0.000000000000000.00000000000000178Kanwar, Neena0000-0002-3923-2453Research Scientist PhDDO, MATerrieFlattTerrie G. Flatt0.000000000000000.00000000000000181Flatt, TerriePhysician and Director, Spanish Language ClinicAuthorship 7857132417076Farooqi MS, Figueroa S, Gotway G, Wang J, Luu HS, Park JYThe Journal of pediatricsFarooqi MS, Figueroa S, Gotway G, Wang J, Luu HS, Park JY. Reinterpretation of Chromosomal Microarrays with Detailed Medical History. J Pediatr. 2020 07; 222:180-185.e1.J Pediatr2020-05-13T00:00:002020Reinterpretation of Chromosomal Microarrays with Detailed Medical History.MDAlainCunaAlain C. Cuna0.000000000000000.00000000000000186Cuna, Alain0000-0002-8174-4487Physician, NeonatologistAuthorship 8146233080408Smith SC, Farooqi MS, Gener MA, Ginn K, Joyce JM, Bendorf TM, Cooley LDThe Journal of molecular diagnostics : JMDSmith SC, Farooqi MS, Gener MA, Ginn K, Joyce JM, Bendorf TM, Cooley LD. Clinical Validation of Somatic Mutation Detection by the OncoScan CNV Plus Assay. J Mol Diagn. 2021 01; 23(1):29-37.J Mol Diagn2020-10-17T00:00:002020Clinical Validation of Somatic Mutation Detection by the OncoScan CNV Plus Assay.Authorship 8358733392505Baker TG, Alden J, Dubuc AM, Welsh CT, Znoyko I, Cooley LD, Farooqi MS, Schwartz S, Li YY, Cherniack AD, Lindhorst SM, Gener M, Wolff DJ, Meredith DMNeuro-oncology advancesBaker TG, Alden J, Dubuc AM, Welsh CT, Znoyko I, Cooley LD, Farooqi MS, Schwartz S, Li YY, Cherniack AD, Lindhorst SM, Gener M, Wolff DJ, Meredith DM. Near haploidization is a genomic hallmark which defines a molecular subgroup of giant cell glioblastoma. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa155.Neurooncol Adv2020-11-12T00:00:002020Near haploidization is a genomic hallmark which defines a molecular subgroup of giant cell glioblastoma.Principal InvestigatorCo-Prinicpal Investigator2024-06-30Masonic Cancer AllianceTerrie Flatt2020-10-01The Genomic and Cellular Landscape in Children and Young Adults with Sarcoma2022-06-30National Cancer InstituteMidhat Farooqi2020-07-01Free the Data: Open Sharing of Comprehensive Genomic Childhood Cancer Datasets3P30CA168524-09S3Authorship 90823Authorship 91491633631350Lansdon LA, Cadieux-Dion M, Yoo B, Miller N, Cohen ASA, Zellmer L, Zhang L, Farrow EG, Thiffault I, Repnikova EA, Cooley LD, Alaimo JT, Porath B, Herriges JC, Saunders CJ, Farooqi MSThe Journal of molecular diagnostics : JMDLansdon LA, Cadieux-Dion M, Yoo B, Miller N, Cohen ASA, Zellmer L, Zhang L, Farrow EG, Thiffault I, Repnikova EA, Cooley LD, Alaimo JT, Porath B, Herriges JC, Saunders CJ, Farooqi MS. Factors Affecting Migration to GRCh38 in Laboratories Performing Clinical Next-Generation Sequencing. J Mol Diagn. 2021 05; 23(5):651-657.J Mol Diagn2021-02-22T00:00:002021Factors Affecting Migration to GRCh38 in Laboratories Performing Clinical Next-Generation Sequencing.33661568Dermott SM, Kucine N, Farooqi MS, Li W, Silvey MPediatric blood & cancerDermott SM, Kucine N, Farooqi MS, Li W, Silvey M. Polycythemia vera in a 2-year-old child with a JAK2 exon 12 deletion. Pediatr Blood Cancer. 2021 07; 68(7):e28994.Pediatr Blood Cancer2021-03-04T00:00:002021Polycythemia vera in a 2-year-old child with a JAK2 exon 12 deletion.Authorship 9691333913590Ahmed AA, Habeebu S, Farooqi MS, Gamis AS, Gonzalez E, Flatt T, Sherman A, Surrey L, Arnold MA, Conces M, Koo S, Dioufa N, Barr FG, Tsokos MGPediatric blood & cancerAhmed AA, Habeebu S, Farooqi MS, Gamis AS, Gonzalez E, Flatt T, Sherman A, Surrey L, Arnold MA, Conces M, Koo S, Dioufa N, Barr FG, Tsokos MG. MYOD1 as a prognostic indicator in rhabdomyosarcoma. Pediatr Blood Cancer. 2021 09; 68(9):e29085.Pediatr Blood Cancer2021-04-29T00:00:002021MYOD1 as a prognostic indicator in rhabdomyosarcoma.PhD, FACMGAnaCohenAna Cohen0.000000000000000.00000000000000209Cohen, AnaAssistant Director Clinical Genome CenterAuthorship 9993434953820Shi G, Xu J, Barnes SF, Farooqi MS, Luu HS, Gotway G, Park JYThe Journal of pediatricsShi G, Xu J, Barnes SF, Farooqi MS, Luu HS, Gotway G, Park JY. Chromosomal Microarray Reinterpretation: Applications to Pediatric Practice. J Pediatr. 2022 Apr; 243:219-223.J Pediatr2021-12-23T00:00:002021Chromosomal Microarray Reinterpretation: Applications to Pediatric Practice.Authorship 10301235158790Ahmed AA, Farooqi MS, Habeebu SS, Gonzalez E, Flatt TG, Wilson AL, Barr FGCancersAhmed AA, Farooqi MS, Habeebu SS, Gonzalez E, Flatt TG, Wilson AL, Barr FG. NanoString Digital Molecular Profiling of Protein and microRNA in Rhabdomyosarcoma. Cancers (Basel). 2022 Jan 21; 14(3).Cancers (Basel)2022-01-21T00:00:002022NanoString Digital Molecular Profiling of Protein and microRNA in Rhabdomyosarcoma.Authorship 104971235869940Lansdon LA, Cadieux-Dion M, Herriges JC, Johnston J, Yoo B, Alaimo JT, Thiffault I, Miller N, Cohen ASA, Repnikova EA, Zhang L, Farooqi MS, Farrow EG, Saunders CJClinical chemistryLansdon LA, Cadieux-Dion M, Herriges JC, Johnston J, Yoo B, Alaimo JT, Thiffault I, Miller N, Cohen ASA, Repnikova EA, Zhang L, Farooqi MS, Farrow EG, Saunders CJ. Clinical Validation of Genome Reference Consortium Human Build 38 in a Laboratory Utilizing Next-Generation Sequencing Technologies. Clin Chem. 2022 09 01; 68(9):1177-1183.Clin Chem2022-09-01T00:00:002022Clinical Validation of Genome Reference Consortium Human Build 38 in a Laboratory Utilizing Next-Generation Sequencing Technologies.Authorship 10691436201717Elsbernd A, Boulouadnine B, Ahmed A, Farooqi M, Sandritter T, Shakhnovich V, Blanding D, Demoulin JB, Thompson JJCO precision oncologyElsbernd A, Boulouadnine B, Ahmed A, Farooqi M, Sandritter T, Shakhnovich V, Blanding D, Demoulin JB, Thompson J. Novel Oncogenic <i>PDGFRB</i> Variant in Severe Infantile Myofibromatosis With Response to Imatinib Using Therapeutic Drug Monitoring. JCO Precis Oncol. 2022 10; 6:e2200250.JCO Precis Oncol2022-10-01T00:00:002022Novel Oncogenic <i>PDGFRB</i> Variant in Severe Infantile Myofibromatosis With Response to Imatinib Using Therapeutic Drug Monitoring.Authorship 1120114Authorship 1129414Authorship 11390436715450Awotoye W, Whitt JC, Yoo B, Farooqi MS, Farrow EG, Allareddy V, Amendt BA, Rengasamy Venugopalan SJournal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyAwotoye W, Whitt JC, Yoo B, Farooqi MS, Farrow EG, Allareddy V, Amendt BA, Rengasamy Venugopalan S. Genetic heterogeneity and enrichment of variants in DNA-repair genes in ameloblastoma. J Oral Pathol Med. 2023 Mar; 52(3):263-270.J Oral Pathol Med2023-02-21T00:00:002023Genetic heterogeneity and enrichment of variants in DNA-repair genes in ameloblastoma.36917897Cooley LD, Lansdon LA, Laurence K, Herriges JC, Zhang L, Repnikova EA, Joyce J, Thakor P, Warren L, Smith SC, Yoo B, Gener M, Ginn KF, Farooqi MSCancer geneticsCooley LD, Lansdon LA, Laurence K, Herriges JC, Zhang L, Repnikova EA, Joyce J, Thakor P, Warren L, Smith SC, Yoo B, Gener M, Ginn KF, Farooqi MS. Integrated genetic profiling of archival pediatric high-grade glial tumors and reassessment with 2021 WHO classification of paediatric CNS tumours. Cancer Genet. 2023 06; 274-275:10-20.Cancer Genet2023-03-05T00:00:002023Integrated genetic profiling of archival pediatric high-grade glial tumors and reassessment with 2021 WHO classification of paediatric CNS tumours.37190159Gonzalez E, Ahmed AA, McCarthy L, Chastain K, Habeebu S, Zapata-Tarres M, Cardenas-Cardos R, Velasco-Hidalgo L, Corcuera-Delgado C, Rodriguez-Jurado R, Garc?a-Rodr?guez L, Parrales A, Iwakuma T, Farooqi MS, Lee B, Weir SJ, Flatt TGCancersGonzalez E, Ahmed AA, McCarthy L, Chastain K, Habeebu S, Zapata-Tarres M, Cardenas-Cardos R, Velasco-Hidalgo L, Corcuera-Delgado C, Rodriguez-Jurado R, Garc?a-Rodr?guez L, Parrales A, Iwakuma T, Farooqi MS, Lee B, Weir SJ, Flatt TG. Perinucleolar Compartment (PNC) Prevalence as an Independent Prognostic Factor in Pediatric Ewing Sarcoma: A Multi-Institutional Study. Cancers (Basel). 2023 Apr 10; 15(8).Cancers (Basel)2023-04-10T00:00:002023Perinucleolar Compartment (PNC) Prevalence as an Independent Prognostic Factor in Pediatric Ewing Sarcoma: A Multi-Institutional Study.true1Research Scientist PhDResearch Scientist PhDtrue1Research Scientist PhDResearch Scientist PhDtrue1Director, Division of Pediatric Nephrology Director, Division of Pediatric Nephrology true1Surgical Director, Transplantation Surgical Director, Transplantation true1Assistant Director Clinical Genome CenterAssistant Director Clinical Genome CenterAuthorship 1168916Authorship 116901037532182Meredith DM, Cooley LD, Dubuc A, Morrissette J, Sussman RT, Nasrallah MP, Rathbun P, Yap KL, Wadhwani N, Bao L, Wolff DJ, Ida C, Sukhanova M, Horbinski C, Jennings LJ, Farooqi M, Gener M, Ginn K, Kam KL, Sasaki K, Kanagal-Shamanna R, Alexandrescu S, Brat D, Lu XModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncMeredith DM, Cooley LD, Dubuc A, Morrissette J, Sussman RT, Nasrallah MP, Rathbun P, Yap KL, Wadhwani N, Bao L, Wolff DJ, Ida C, Sukhanova M, Horbinski C, Jennings LJ, Farooqi M, Gener M, Ginn K, Kam KL, Sasaki K, Kanagal-Shamanna R, Alexandrescu S, Brat D, Lu X. ROS1 Alterations as a Potential Driver of Gliomas in Infant, Pediatric, and Adult Patients. Mod Pathol. 2023 Nov; 36(11):100294.Mod Pathol2023-07-31T00:00:002023ROS1 Alterations as a Potential Driver of Gliomas in Infant, Pediatric, and Adult Patients.37476329Galbraith K, Vasudevaraja V, Serrano J, Shen G, Tran I, Abdallat N, Wen M, Patel S, Movahed-Ezazi M, Faustin A, Spino-Keeton M, Roberts LG, Maloku E, Drexler SA, Liechty BL, Pisapia D, Krasnozhen-Ratush O, Rosenblum M, Shroff S, Bou? DR, Davidson C, Mao Q, Suchi M, North P, Hopp A, Segura A, Jarzembowski JA, Parsons L, Johnson MD, Mobley B, Samore W, McGuone D, Gopal PP, Canoll PD, Horbinski C, Fullmer JM, Farooqui MS, Gokden M, Wadhwani NR, Richardson TE, Umphlett M, Tsankova NM, DeWitt JC, Sen C, Placantonakis DG, Pacione D, Wisoff JH, Teresa Hidalgo E, Harter D, William CM, Cordova C, Kurz SC, Barbaro M, Orringer DA, Karajannis MA, Sulman EP, Gardner SL, Zagzag D, Tsirigos A, Allen JC, Golfinos JG, Snuderl MNeuro-oncology advancesGalbraith K, Vasudevaraja V, Serrano J, Shen G, Tran I, Abdallat N, Wen M, Patel S, Movahed-Ezazi M, Faustin A, Spino-Keeton M, Roberts LG, Maloku E, Drexler SA, Liechty BL, Pisapia D, Krasnozhen-Ratush O, Rosenblum M, Shroff S, Bou? DR, Davidson C, Mao Q, Suchi M, North P, Hopp A, Segura A, Jarzembowski JA, Parsons L, Johnson MD, Mobley B, Samore W, McGuone D, Gopal PP, Canoll PD, Horbinski C, Fullmer JM, Farooqui MS, Gokden M, Wadhwani NR, Richardson TE, Umphlett M, Tsankova NM, DeWitt JC, Sen C, Placantonakis DG, Pacione D, Wisoff JH, Teresa Hidalgo E, Harter D, William CM, Cordova C, Kurz SC, Barbaro M, Orringer DA, Karajannis MA, Sulman EP, Gardner SL, Zagzag D, Tsirigos A, Allen JC, Golfinos JG, Snuderl M. Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines for clinical testing. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad076.Neurooncol Adv2023-06-26T00:00:002023Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines for clinical testing.Authorship 11957337877563Gonzalez E, Flatt TG, Farooqi M, Johnson L, Ahmed AACurrent molecular medicineGonzalez E, Flatt TG, Farooqi M, Johnson L, Ahmed AA. Polypyrimidine Tract Binding Protein: A Universal Player in Cancer Development. Curr Mol Med. 2023 Oct 24.Curr Mol Med2023-10-24T00:00:002023Polypyrimidine Tract Binding Protein: A Universal Player in Cancer Development.D001932Disorders12440.952559Brain NeoplasmsPhDBrookeFridleyBrooke Fridley0.000000000000000.00000000000000222Fridley, BrookeDirector, Biostatistics and Epidemiology Coretrue1Director, Biostatistics and Epidemiology CoreDirector, Biostatistics and Epidemiology Coretrue1Director, Molecular Oncology, Center for Pediatric Genomic MedicineDirector, Molecular Oncology, Center for Pediatric Genomic Medicine2Associate ProfessorAssociate Professor3Clinical Assistant ProfessorClinical Assistant Professortrue1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Physician, NeonatologistPhysician, Neonatologisttrue1Physician and Director, Spanish Language ClinicPhysician and Director, Spanish Language Clinictrue1Director, Center for Pediatric Genomic Medicine Director, Center for Pediatric Genomic Medicine true1Director of Lab OperationsDirector of Lab Operationstrue1Hematology/Oncology PediatricianHematology/Oncology Pediatriciantrue1Neuro-Oncologist and Director, Pediatric Brain Tumor ProgramNeuro-Oncologist and Director, Pediatric Brain Tumor Programtrue1Medical Chairman Medical Chairman D005910Disorders6260.965062Glioma