D066298Concepts & IdeasProceduresE05.48110210.995256In Vitro Techniquescmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson22484150Converse GL, Armstrong M, Quinn RW, Buse EE, Cromwell ML, Moriarty SJ, Lofland GK, Hilbert SL, Hopkins RAActa biomaterialiaConverse GL, Armstrong M, Quinn RW, Buse EE, Cromwell ML, Moriarty SJ, Lofland GK, Hilbert SL, Hopkins RA. Effects of cryopreservation, decellularization and novel extracellular matrix conditioning on the quasi-static and time-dependent properties of the pulmonary valve leaflet. Acta Biomater. 2012 Jul; 8(7):2722-9.Acta Biomater2012-04-04T00:00:002012Effects of cryopreservation, decellularization and novel extracellular matrix conditioning on the quasi-static and time-dependent properties of the pulmonary valve leaflet.26138612Goldman JL, Leeder JS, Van Haandel L, Pearce REDrug metabolism and disposition: the biological fate of chemicalsGoldman JL, Leeder JS, Van Haandel L, Pearce RE. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015 Sep; 43(9):1372-80.Drug Metab Dispos2015-07-02T00:00:002015In Vitro Hepatic Oxidative Biotransformation of Trimethoprim.27895113Boberg M, Vrana M, Mehrotra A, Pearce RE, Gaedigk A, Bhatt DK, Leeder JS, Prasad BDrug metabolism and disposition: the biological fate of chemicalsBoberg M, Vrana M, Mehrotra A, Pearce RE, Gaedigk A, Bhatt DK, Leeder JS, Prasad B. Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants. Drug Metab Dispos. 2017 02; 45(2):216-223.Drug Metab Dispos2016-11-28T00:00:002016Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants.28960269Burgess KS, Ipe J, Swart M, Metzger IF, Lu J, Gufford BT, Thong N, Desta Z, Gaedigk R, Pearce RE, Gaedigk A, Liu Y, Skaar TCClinical pharmacology and therapeuticsBurgess KS, Ipe J, Swart M, Metzger IF, Lu J, Gufford BT, Thong N, Desta Z, Gaedigk R, Pearce RE, Gaedigk A, Liu Y, Skaar TC. Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs. Clin Pharmacol Ther. 2018 07; 104(1):130-138.Clin Pharmacol Ther2017-10-25T00:00:002017Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs.MDJenniferGoldmanJennifer L. Goldman87Goldman, JenniferDirector, Drug Safety Service3Assistant Professor1ProfessorSurgeryMDShawnSt PeterShawn D St Peter0.000000000000000.00000000000000131St Peter, ShawnMedical Chairman 0.301610.004294610research area of0.201250.0086301433subject area forPediatricsResearchClinicalPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstitutePhDTaejuParkTaeju Park0.000000000000000.0000000000000041Park, Taeju0000-0003-3897-3994Research Faculty PhDChildren's Mercy Kansas City33561443Park T, Large N, Curran TThe Journal of biological chemistryPark T, Large N, Curran T. Quantitative assessment of glioblastoma phenotypes in?vitro establishes cell migration as a robust readout of Crk and CrkL activity. J Biol Chem. 2021 Jan-Jun; 296:100390.J Biol Chem2021-02-06T00:00:002021Quantitative assessment of glioblastoma phenotypes in?vitro establishes cell migration as a robust readout of Crk and CrkL activity.true1Research Faculty PhDResearch Faculty PhDtrue1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Director, Drug Safety ServiceDirector, Drug Safety Servicetrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research Institutetrue1Medical Chairman Medical Chairman