Create The International Center for Indigenous Phytotherapy Studies (TICIPS). Dr. Goggin is Co-Leader of Research Project I which is a randomized double blind placebo controlled study to investigate the safety and efficacy of Lessertia frutescens in HIV-infected South Africans with early disease. The specific goals of this study are to: 1) determine the safety of Lessertia frutescens when used by HIV-1 infected adults with early disease, 2) determine the effect of Lessertia frutescens on secondary and Tertiary outcomes, and 3) document the impact of Lessertia frutescens on markers of HIV disease progression.