30257076Shakhnovich V, Abdel-Rahman S, Friesen CA, Weigel J, Pearce RE, Gaedigk A, Leeder JS, Kearns GLPediatric obesityBody Weight; Gastroesophageal Reflux; Pantoprazole; Pediatric Obesity; Proton Pump InhibitorsAdolescent; Child; Cytochrome P-450 CYP2C19; Drug Dosage Calculations; Female; Follow-Up Studies; Genotype; Humans; Male; Prospective StudiesShakhnovich V, Abdel-Rahman S, Friesen CA, Weigel J, Pearce RE, Gaedigk A, Leeder JS, Kearns GL. Lean body weight dosing avoids excessive systemic exposure to proton pump inhibitors for children with obesity. Pediatr Obes. 2019 01; 14(1).Pediatr Obes2018-09-26T00:00:002018Lean body weight dosing avoids excessive systemic exposure to proton pump inhibitors for children with obesity.cmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD008297Physiology11633280.54802MaleD011446Concepts & IdeasProcedures725220.854676Prospective Studies1ProfessorAuthorship 34420.3416320.1708164authors10.2514has subject areaAuthorship 43146Authorship 43157D054328Chemicals & Drugs9130.982063Proton Pump InhibitorsD054796Concepts & IdeasProcedures10170.980165Drug Dosage CalculationsAuthorship 57463MDCraigFriesenCraig A. Friesen0.000000000000000.00000000000000149Friesen, CraigAssociate Division Director, GastroenterologyD063766Disorders291280.814798Pediatric ObesityD000293Living Beings10621370.61882AdolescentD065731Chemicals & Drugs12550.96451Cytochrome P-450 CYP2C19PediatricsResearchClinicalPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteChildren's Mercy Kansas CityD001835Concepts & IdeasPhysiology25560.973727Body Weighttrue1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Associate Division Director, GastroenterologyAssociate Division Director, Gastroenterologytrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research InstituteD002648Living Beings11632570.520082ChildD005260Physiology11835990.534568FemaleD005500Procedures673270.907969Follow-Up StudiesD005764Disorders13450.937124Gastroesophageal RefluxD005838Physiology404010.883905GenotypeD006801Living Beings12067970.397999Humans