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Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.
Reisman SA, Csanaky IL, Aleksunes LM, Klaassen CD. Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. Toxicol Sci. 2009 May; 109(1):31-40.
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PubMed
subject areas
Acetaminophen
Adaptor Proteins, Signal Transducing
Animals
Bile
Biotransformation
Carrier Proteins
Cytoskeletal Proteins
Gene Knockdown Techniques
Guinea Pigs
Liver
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Microscopy, Fluorescence
Microsomes, Liver
NAD(P)H Dehydrogenase (Quinone)
NADPH Dehydrogenase
NF-E2-Related Factor 2
Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.