18328428Kimura H, Ng JM, Curran TCancer cellAntineoplastic Agents; Bone and Bones; Chondrocytes; Hedgehog Proteins; Receptors, G-Protein-Coupled; Signal TransductionAdministration, Oral; Aging; Animals; Animals, Newborn; Bone Remodeling; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cerebellar Neoplasms; Dose-Response Relationship, Drug; Growth Plate; Kruppel-Like Transcription Factors; Luciferases; Medulloblastoma; Mice; Mice, Transgenic; Microscopy, Fluorescence; Microscopy, Video; Osteogenesis; Recombinant Fusion Proteins; Smoothened Receptor; Time Factors; Zinc Finger Protein GLI1Kimura H, Ng JM, Curran T. Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure. Cancer Cell. 2008 Mar; 13(3):249-60.Cancer Cell2008-03-01T00:00:002008Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure.prns:hasAuthorListauthor listprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAuthorshipvivo:hasSubjectAreahas subject areaInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedInformationResourcelinked information resourcerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptD008156Chemicals & Drugs560.998838LuciferasesD008527Disorders490.985355MedulloblastomaD008822Living Beings13330.988518Mice, TransgenicD008856Procedures330.998706Microscopy, FluorescenceD010012Physiology770.996712OsteogenesisD011993Chemicals & Drugs6120.990711Recombinant Fusion ProteinsD013997Concepts & Ideas612470.920232Time FactorsD015398Physiology321110.935367Signal TransductionD016723Physiology110.997202Bone RemodelingAuthorship 13680.1641890.1641892authors10.2528has subject areaD018715ProceduresMicroscopy, VideoD019902AnatomyChondrocytesD043562Chemicals & Drugs770.995699Receptors, G-Protein-CoupledD049109Physiology26560.977282Cell ProliferationD051379Living Beings513120.910614MiceD051741Chemicals & Drugs460.998373Kruppel-Like Transcription FactorsD053823Chemicals & Drugs450.997645Hedgehog ProteinsD000284Procedures23620.982389Administration, OralAuthorship 6004D000375Concepts & IdeasPhysiology14340.972414AgingD000818Living Beings726640.834746AnimalsD000831Living Beings11530.974102Animals, NewbornD000970Chemicals & Drugs20570.947703Antineoplastic AgentsD001842Anatomy5160.992887Bone and BonesD002113Physiology330.99825Calcification, PhysiologicD002454Physiology20440.976137Cell DifferentiationD002478Anatomy30760.979689Cells, CulturedD002528Disorders240.996002Cerebellar NeoplasmsD004305Concepts & Ideas38950.95931Dose-Response Relationship, DrugD006132AnatomyGrowth Plate