D015662Chemicals & DrugsD02.065.884.725.867.500D02.092.146.807.867.500D02.886.590.700.725.867.500D03.383.742.906.500D26.310.8755130.970954Trimethoprim, Sulfamethoxazole Drug Combinationcmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson24380396van Haandel L, Goldman JL, Pearce RE, Leeder JSChemical research in toxicologyvan Haandel L, Goldman JL, Pearce RE, Leeder JS. Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children. Chem Res Toxicol. 2014 Feb 17; 27(2):211-8.Chem Res Toxicol2014-01-13T00:00:002014Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children.29869446Goldman JL, van Haandel LPharmacoepidemiology and drug safetyGoldman JL, van Haandel L. Trimethoprim: The overlooked component of trimethoprim-sulfamethoxazole idiosyncratic adverse drug reactions. Pharmacoepidemiol Drug Saf. 2018 08; 27(8):949-951.Pharmacoepidemiol Drug Saf2018-06-04T00:00:002018Trimethoprim: The overlooked component of trimethoprim-sulfamethoxazole idiosyncratic adverse drug reactions.3.979870.05297465research area of0.8643770.1046479subject area forMD, PhDTomiPastinenTomi Pastinen0.000000000000000.00000000000000113Pastinen, TomiDirector, Center for Pediatric Genomic Medicine MD, MSCRBridgetteJonesBridgette L. Jones57Jones, BridgettePhysicianMDJenniferGoldmanJennifer L. Goldman87Goldman, JenniferDirector, Drug Safety Service1Professor23Director31142578Miller JO, Taylor J, Goldman JLPediatricsMiller JO, Taylor J, Goldman JL. Severe Acute Respiratory Failure in Healthy Adolescents Exposed to Trimethoprim-Sulfamethoxazole. Pediatrics. 2019 06; 143(6).Pediatrics2019-06-01T00:00:002019Severe Acute Respiratory Failure in Healthy Adolescents Exposed to Trimethoprim-Sulfamethoxazole.PediatricsResearchClinicalPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteChildren's Mercy Kansas CityPhDPaulTorenPaul C. Toren0.000000000000000.00000000000000164Toren, PaulDirector, Analytical Chemistry Core33513317Miller JO, Shih AR, Mino-Kenudson M, Taylor MS, Goldman JLAmerican journal of respiratory and critical care medicineMiller JO, Shih AR, Mino-Kenudson M, Taylor MS, Goldman JL. Trimethoprim-Sulfamethoxazole-associated Fulminant Respiratory Failure in Children and Young Adults. Am J Respir Crit Care Med. 2021 04 01; 203(7):918-921.Am J Respir Crit Care Med2021-04-01T00:00:002021Trimethoprim-Sulfamethoxazole-associated Fulminant Respiratory Failure in Children and Young Adults.35169303Goldman JL, Miller JO, Miller N, Eveleigh R, Gibson A, Phillips EJ, Pastinen TThe pharmacogenomics journalGoldman JL, Miller JO, Miller N, Eveleigh R, Gibson A, Phillips EJ, Pastinen T. HLA-B*07:02 and HLA-C*07:02 are associated with trimethoprim-sulfamethoxazole respiratory failure. Pharmacogenomics J. 2022 03; 22(2):124-129.Pharmacogenomics J2022-02-16T00:00:002022HLA-B*07:02 and HLA-C*07:02 are associated with trimethoprim-sulfamethoxazole respiratory failure.true1Director, Analytical Chemistry CoreDirector, Analytical Chemistry Coretrue1Director, Center for Pediatric Genomic Medicine Director, Center for Pediatric Genomic Medicine true1PhysicianPhysiciantrue1Director, Drug Safety ServiceDirector, Drug Safety Servicetrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research Institute