D014150Chemicals & DrugsPhysiologyD27.505.696.277.950.040D27.505.954.427.210.950.040D27.505.954.427.700.872.3316140.974281Antipsychotic Agentscmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson3.248990.04516036research area of0.9899920.16706510subject area forMDRyanFischerRyan T. Fischer0.000000000000000.00000000000000101Fischer, RyanChief, Section of Hepatology and Transport Medicine 1Professor23DirectorPediatricsResearchClinicalPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteChildren's Mercy Kansas CityPhDPaulTorenPaul C. Toren0.000000000000000.00000000000000164Toren, PaulDirector, Analytical Chemistry Core32847865Chapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JSDrug metabolism and disposition: the biological fate of chemicalsChapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JS. The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites. Drug Metab Dispos. 2020 11; 48(11):1113-1120.Drug Metab Dispos2020-08-26T00:00:002020The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites.33147643Bousman CA, Bengesser SA, Aitchison KJ, Amare AT, Aschauer H, Baune BT, Asl BB, Bishop JR, Burmeister M, Chaumette B, Chen LS, Cordner ZA, Deckert J, Degenhardt F, DeLisi LE, Folkersen L, Kennedy JL, Klein TE, McClay JL, McMahon FJ, Musil R, Saccone NL, Sangkuhl K, Stowe RM, Tan EC, Tiwari AK, Zai CC, Zai G, Zhang J, Gaedigk A, M?ller DJPharmacopsychiatryBousman CA, Bengesser SA, Aitchison KJ, Amare AT, Aschauer H, Baune BT, Asl BB, Bishop JR, Burmeister M, Chaumette B, Chen LS, Cordner ZA, Deckert J, Degenhardt F, DeLisi LE, Folkersen L, Kennedy JL, Klein TE, McClay JL, McMahon FJ, Musil R, Saccone NL, Sangkuhl K, Stowe RM, Tan EC, Tiwari AK, Zai CC, Zai G, Zhang J, Gaedigk A, M?ller DJ. Review and Consensus on Pharmacogenomic Testing in Psychiatry. Pharmacopsychiatry. 2021 Jan; 54(1):5-17.Pharmacopsychiatry2020-11-04T00:00:002020Review and Consensus on Pharmacogenomic Testing in Psychiatry.33603025Hongkaew Y, Gaedigk A, Wilffert B, Ngamsamut N, Kittitharaphan W, Limsila P, Sukasem CScientific reportsHongkaew Y, Gaedigk A, Wilffert B, Ngamsamut N, Kittitharaphan W, Limsila P, Sukasem C. Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone. Sci Rep. 2021 02 18; 11(1):4158.Sci Rep2021-02-18T00:00:002021Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone.true1Director, Analytical Chemistry CoreDirector, Analytical Chemistry CorePhDLauraRamseyLaura Ramsey0.000000000000000.00000000000000221Ramsey, Laura0000-0001-6417-3961Doctoral Research Facultytrue1Doctoral Research FacultyDoctoral Research Faculty34032507Rossow KM, Vaughn SE, Strawn JR, Van Driest SL, Ramsey LBPharmacogenomicsRossow KM, Vaughn SE, Strawn JR, Van Driest SL, Ramsey LB. The need for a refined understanding of CYP2D6 in second-generation antipsychotic outcomes in children and adolescents. Pharmacogenomics. 2021 06; 22(8):447-450.Pharmacogenomics2021-05-25T00:00:002021The need for a refined understanding of CYP2D6 in second-generation antipsychotic outcomes in children and adolescents.38377522Kanu AA, Johnston MM, Poweleit EA, Vaughn SE, Strawn JR, Ramsey LBJournal of child and adolescent psychopharmacologyKanu AA, Johnston MM, Poweleit EA, Vaughn SE, Strawn JR, Ramsey LB. Influence of CYP2D6 Metabolizer Status on Risperidone and Paliperidone Tolerability in Children and Adolescents. J Child Adolesc Psychopharmacol. 2024 Feb; 34(1):34-41.J Child Adolesc Psychopharmacol2024-02-01T00:00:002024Influence of CYP2D6 Metabolizer Status on Risperidone and Paliperidone Tolerability in Children and Adolescents.true1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Chief, Section of Hepatology and Transport Medicine Chief, Section of Hepatology and Transport Medicine true1Deputy Director, Children's Research InstituteDeputy Director, Children's Research Institute