18463198Pearce RE, Lu W, Wang Y, Uetrecht JP, Correia MA, Leeder JSDrug metabolism and disposition: the biological fate of chemicalsAnticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme SystemAnimals; Biotransformation; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Mice; Microsomes, LiverPearce RE, Lu W, Wang Y, Uetrecht JP, Correia MA, Leeder JS. Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine. Drug Metab Dispos. 2008 Aug; 36(8):1637-49.Drug Metab Dispos2008-05-07T00:00:002008Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine.cmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD008862Anatomy6420.967198Microsomes, LiverAuthorship 310Authorship 31160.332580.166292authors10.2510has subject areaD013058Procedures8170.993175Mass Spectrometry1ProfessorD051379Living Beings513120.910614MicePediatricsResearchPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteChildren's Mercy Kansas CityD000818Living Beings726640.834746AnimalsD000927Chemicals & Drugs8250.981365AnticonvulsantsD001711Physiology5490.980439BiotransformationD002220Chemicals & Drugs2100.992771Carbamazepinetrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research InstituteD002851Procedures13410.981746Chromatography, High Pressure LiquidD003577Chemicals & Drugs6880.933256Cytochrome P-450 Enzyme SystemD006801Living Beings12067970.397999Humans