16291717Shelepova T, Nafziger AN, Victory J, Kashuba AD, Rowland E, Zhang Y, Sellers E, Kearns G, Leeder JS, Gaedigk A, Bertino JSJournal of clinical pharmacologyArylamine N-Acetyltransferase; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Ethinyl Estradiol; NorgestrelAdult; Caffeine; Cross-Over Studies; Dextromethorphan; Drug Combinations; Drug Interactions; Female; Genotype; Humans; Midazolam; Omeprazole; Therapeutic Equivalency; Vitamin K; Warfarin; Xanthine OxidaseShelepova T, Nafziger AN, Victory J, Kashuba AD, Rowland E, Zhang Y, Sellers E, Kearns G, Leeder JS, Gaedigk A, Bertino JS. Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail. J Clin Pharmacol. 2005 Dec; 45(12):1413-21.J Clin Pharmacol2005-12-01T00:00:002005Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail.cmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:hasSubjectAreaMajorTopicListhas major subject area listprns:hasSubjectAreaMinorTopicListhas minor subject area listprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifiervivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasSubjectAreahas subject areavivo:hrJobTitleHR job titleInformation Resourcevivo:informationResourceInAuthorshipauthorsvivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonD008874Chemicals & Drugs3110.997377MidazolamD009644Chemicals & Drugs220.999298NorgestrelD009853Chemicals & Drugs3120.995816OmeprazoleAuthorship 23410Authorship 23590.07025050.07025052authors10.2520has subject areaD013810Concepts & Ideas340.999638Therapeutic EquivalencyD014812Chemicals & Drugs350.997213Vitamin KD014859Chemicals & Drugs3120.994453WarfarinD014969Chemicals & Drugs2140.997053Xanthine OxidaseD018592Procedures20320.990306Cross-Over Studies1ProfessorPediatricsResearchPhD, MSAndreaGaedigkAndrea Gaedigk39.08346750000000-94.577112900000001Gaedigk, Andrea0000-0001-6968-1893Director, Pharmacogenetics Core LaboratoryPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteD000328Living Beings11012590.736773AdultChildren's Mercy Kansas CityD001191Chemicals & Drugs4180.995386Arylamine N-AcetyltransferaseD002110Chemicals & Drugs2120.996747Caffeinetrue1Director, Pharmacogenetics Core LaboratoryDirector, Pharmacogenetics Core Laboratorytrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research InstituteD003276Chemicals & Drugs220.999298Contraceptives, OralD003577Chemicals & Drugs6880.933256Cytochrome P-450 Enzyme SystemD003915Chemicals & Drugs4570.975487DextromethorphanD004338Chemicals & Drugs8180.996389Drug CombinationsD004347Physiology9300.989511Drug InteractionsD004997Chemicals & Drugs220.999298Ethinyl EstradiolD005260Physiology11835990.534568FemaleD005838Physiology404010.883905GenotypeD006801Living Beings12067970.397999Humans