 Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
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| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
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| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
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Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 2 | 3 | 5 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 6 | 7 | | 2016 | 1 | 2 | 3 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 4 | 5 | | 2019 | 2 | 5 | 7 | | 2020 | 0 | 3 | 3 | | 2022 | 1 | 2 | 3 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Riddell MC, Li Z, Gal RL, Calhoun P, Jacobs PG, Clements MA, Martin CK, Doyle Iii FJ, Patton SR, Castle JR, Gillingham MB, Beck RW, Rickels MR. Examining the Acute Glycemic Effects of Different Types of Structured Exercise Sessions in Type 1 Diabetes in a Real-World Setting: The Type 1 Diabetes and Exercise Initiative (T1DEXI). Diabetes Care. 2023 04 01; 46(4):704-713.
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McVean J, Forlenza GP, Beck RW, Bauza C, Bailey R, Buckingham B, DiMeglio LA, Sherr JL, Clements M, Neyman A, Evans-Molina C, Sims EK, Messer LH, Ekhlaspour L, McDonough R, Van Name M, Rojas D, Beasley S, DuBose S, Kollman C, Moran A. Effect of Tight Glycemic Control on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial. JAMA. 2023 03 28; 329(12):980-989.
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Patton SR, Fox L, Cushing CC, McDonough R, Clements MA. Cash-Only INcentives to promote insulin DOSE engagement: A protocol paper for the pilot randomized controlled trial of COIN2DOSE. Contemp Clin Trials. 2022 12; 123:107008.
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Yang CH, Fagnocchi L, Apostle S, Wegert V, Casan?-Gald?n S, Landgraf K, Panzeri I, Dror E, Heyne S, W?rpel T, Chandler DP, Lu D, Yang T, Gibbons E, Guerreiro R, Bras J, Thomasen M, Grunnet LG, Vaag AA, Gillberg L, Grundberg E, Conesa A, K?rner A, Pospisilik JA. Independent phenotypic plasticity axes define distinct obesity sub-types. Nat Metab. 2022 09; 4(9):1150-1165.
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Li X, Shao X, Bazzano LA, Xue Q, Koseva BS, Grundberg E, Shai I, Bray GA, Sacks FM, Qi L. Blood DNA methylation at TXNIP and glycemic changes in response to weight-loss diet interventions: the POUNDS lost trial. Int J Obes (Lond). 2022 06; 46(6):1122-1127.
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Gillingham MB, Li Z, Beck RW, Calhoun P, Castle JR, Clements M, Dassau E, Doyle FJ, Gal RL, Jacobs P, Patton SR, Rickels MR, Riddell M, Martin CK. Assessing Mealtime Macronutrient Content: Patient Perceptions Versus Expert Analyses via a Novel Phone App. Diabetes Technol Ther. 2021 02; 23(2):85-94.
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McConville A, Noser AE, Clements MA, Patton SR. Mealtime insulin BOLUS score increases prior to clinic visits in youth with type 1 diabetes. BMJ Open Diabetes Res Care. 2020 07; 8(1).
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Clements MA, Patton SR, McDonough RJ, Artman M. Are we there yet? Advanced technologies for young children with type 1 diabetes: comment in response to "Type 1 diabetes mellitus management in young children: implementation of current technologies". Pediatr Res. 2020 03; 87(4):616-618.
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Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, Knip M, Jacobsen L, Krischer JP, Long SA, Lundgren M, McKinney EF, Morgan NG, Oram RA, Pastinen T, Peters MC, Petrelli A, Qian X, Redondo MJ, Roep BO, Schatz D, Skibinski D, Peakman M. Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes Care. 2020 01; 43(1):5-12.
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Marker AM, Monzon AD, Nelson EL, Clements MA, Patton SR. An Intervention to Reduce Hypoglycemia Fear in Parents of Young Kids with Type 1 Diabetes Through Video-Based Telemedicine (REDCHiP): Trial Design, Feasibility, and Acceptability. Diabetes Technol Ther. 2020 01; 22(1):25-33.
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