 Hirschsprung Disease
"Hirschsprung Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Descriptor ID |
D006627
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| MeSH Number(s) |
C06.198.439 C06.405.469.158.701.439 C16.131.314.439
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| Concept/Terms |
Hirschsprung Disease- Hirschsprung Disease
- Disease, Hirschsprung
- Megacolon, Congenital
- Hirschsprung's Disease
- Disease, Hirschsprung's
- Hirschsprungs Disease
- Megacolon, Aganglionic
- Aganglionic Megacolon
- Congenital Megacolon
Aganglionosis, Colonic- Aganglionosis, Colonic
- Colonic Aganglionosis
- Total Colonic Aganglionosis
- Aganglionosis, Total Colonic
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Below are MeSH descriptors whose meaning is more general than "Hirschsprung Disease".
Below are MeSH descriptors whose meaning is more specific than "Hirschsprung Disease".
This graph shows the total number of publications written about "Hirschsprung Disease" by people in this website by year, and whether "Hirschsprung Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 3 | 0 | 3 | | 2017 | 2 | 0 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 5 | 0 | 5 | | 2020 | 1 | 0 | 1 | | 2021 | 9 | 0 | 9 | | 2022 | 4 | 0 | 4 | | 2023 | 1 | 0 | 1 | | 2024 | 4 | 1 | 5 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hirschsprung Disease" by people in Profiles.
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Alexander AJ, Short SS, Putnam A, Avansino JR, Badillo A, Crady RC, Dickie BH, Reeder RW, Rentea RM, Speck KE, Wood RJ, Rollins MD. Anorectal Malformation Fistula Evaluation May Aid in Hirschsprung Diagnosis. J Surg Res. 2025 Jun; 310:30-34.
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Bokova E, Elhalaby I, Dow B, Reeves PT, Rentea RM. Hirschsprung-associated Enterocolitis Action Plan: A Pictographic Tool for Caregivers of Children With Hirschsprung Disease. J Pediatr Surg. 2025 Jun; 60(6):162269.
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Alexander AJ, Short SS, Austin K, Avansino JR, Badillo A, Calkins CM, Crady RC, Durham MM, Fuller MK, Reeder RW, Rentea RM, Saadai P, Speck KE, Wood RJ, Harris JC, Rollins MD. Outcomes Following Fecal Diversion for Intractable Hirschsprung Associated Enterocolitis: A Study From the Pediatric Colorectal and Pelvic Learning Consortium. J Pediatr Surg. 2025 Mar; 60(3):162078.
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Rentea RM, Bokova E, Frischer JS, Gosain A, Langer JC, Levitt MA, Nandivada P, Rialon KL, Rollins MD, Segura B, Wood RJ, Lim IIP. Evaluation and Management of Total Colonic Hirschsprung Disease: A Comprehensive Review From the American Pediatric Surgical Association (APSA) Hirschsprung Disease Interest Group. J Pediatr Surg. 2024 Nov; 59(11):161677.
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Lim IIP, Rentea RM. Commentary- Bridging the Gap: The Impact of Bowel Management Programs on Daily Life in Pediatric Colorectal Disease. J Pediatr Surg. 2024 Oct; 59(10):161624.
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Ullrich S, Austin K, Avansino JR, Badillo A, Calkins CM, Crady RC, Durham MM, Fuller MK, Rana A, Reeder RW, Rentea RM, Rollins MD, Saadai P, Speck KE, Wood RJ, van Leeuwen K, Frischer JS. Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium. J Pediatr Surg. 2024 Jul; 59(7):1250-1255.
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Bokova E, Prasade N, Lewis WE, Feira CN, Lim IIP, Oyetunji TA, Rentea RM. Evaluation of Post-neonatal Intensive Care Unit Home Irrigations Prior to Pull-through: Implications for Hirschsprung Disease Management. J Pediatr Surg. 2024 Jul; 59(7):1245-1249.
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Encisco EM, Lim IIP, Velazco CS, Rosen NG, Garrison AP, Rymeski B, Frischer JS. Hirschsprung-Associated Enterocolitis at a Referral Institution: A?Retrospective Review. J Pediatr Surg. 2023 Aug; 58(8):1578-1581.
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Sutthatarn P, Lapidus-Krol E, Smith C, Halaweish I, Rialon K, Ralls MW, Rentea RM, Madonna MB, Haddock C, Rocca AM, Gosain A, Frischer J, Piper H, Goldstein AM, Saadai P, Durham MM, Dickie B, Jafri M, Langer JC. Hirschsprung-associated inflammatory bowel disease: A multicenter study from the APSA Hirschsprung disease interest group. J Pediatr Surg. 2023 May; 58(5):856-861.
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Berrios C, Bollinger J, Yan J, Biesecker B, Chakravarti A. Identifying Needs, Challenges, and Benefits Among Adults and Parents of Children With Hirschsprung Disease. J Pediatr Gastroenterol Nutr. 2022 05 01; 74(5):e103-e108.
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