 Cell Differentiation
"Cell Differentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
| Descriptor ID |
D002454
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| MeSH Number(s) |
G04.299.151
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| Concept/Terms |
Cell Differentiation- Cell Differentiation
- Differentiation, Cell
- Cell Differentiations
- Differentiations, Cell
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Below are MeSH descriptors whose meaning is more general than "Cell Differentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Differentiation".
This graph shows the total number of publications written about "Cell Differentiation" by people in this website by year, and whether "Cell Differentiation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 3 | 5 | | 2012 | 1 | 3 | 4 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 2 | 2 | | 2017 | 0 | 2 | 2 | | 2018 | 2 | 2 | 4 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 3 | 4 | | 2021 | 0 | 2 | 2 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 2 | 2 | | 2024 | 2 | 1 | 3 | | 2025 | 0 | 1 | 1 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cell Differentiation" by people in Profiles.
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Geanes ES, Greening G, Aggelakopoulou M, Truong LH, Khanal S, LeMaster C, Herman M, McLennan R, Borrow P, Bradley T. Bromodomain and extra-terminal protein inhibitors modulate natural killer cell function and differentiation. Sci Rep. 2026 Jan 03; 16(1):3465.
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Varberg KM, Moreno-Irusta A, Novoa A, Musser B, Varberg JM, Goering JP, Saadi I, Iqbal K, Okae H, Arima T, Williams J, Pisarska MD, Soares MJ. Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells. Commun Biol. 2025 Jul 01; 8(1):964.
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Morrison JA, Pushel I, McLennan R, McKinney MC, Gogol MM, Scott A, Krumlauf R, Kulesa PM. Comparative analysis of neural crest development in the chick and mouse. Dev Biol. 2025 03; 519:142-149.
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Mbah NE, Myers AL, Sajjakulnukit P, Chung C, Thompson JK, Hong HS, Giza H, Dang D, Nwosu ZC, Shan M, Sweha SR, Maydan DD, Chen B, Zhang L, Magnuson B, Zhu Z, Radyk M, Lavoie B, Yadav VN, Koo I, Patterson AD, Wahl DR, Franchi L, Agnihotri S, Koschmann CJ, Venneti S, Lyssiotis CA. Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma. Nat Commun. 2024 10 17; 15(1):8983.
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Gong M, Li J, Qin Z, Machado Bressan Wilke MV, Liu Y, Li Q, Liu H, Liang C, Morales-Rosado JA, Cohen ASA, Hughes SS, Sullivan BR, Waddell V, van den Boogaard MH, van Jaarsveld RH, van Binsbergen E, van Gassen KL, Wang T, Hiatt SM, Amaral MD, Kelley WV, Zhao J, Feng W, Ren C, Yu Y, Boczek NJ, Ferber MJ, Lahner C, Elliott S, Ruan Y, Mignot C, Keren B, Xie H, Wang X, Popp B, Zweier C, Piard J, Coubes C, Mau-Them FT, Safraou H, Innes AM, Gauthier J, Michaud JL, Koboldt DC, Sylvie O, Willems M, Tan WH, Cogne B, Rieubland C, Braun D, McLean SD, Platzer K, Zacher P, Oppermann H, Evenepoel L, Blanc P, El Khattabi L, Haque N, Dsouza NR, Zimmermann MT, Urrutia R, Klee EW, Shen Y, Du H, Rappaport L, Liu CM, Chen X. MARK2 variants cause autism spectrum disorder via the downregulation of WNT/?-catenin signaling pathway. Am J Hum Genet. 2024 Nov 07; 111(11):2392-2410.
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Shukla V, Moreno-Irusta A, Varberg KM, Kuna M, Iqbal K, Galligos AM, Aplin JD, Choudhury RH, Okae H, Arima T, Soares MJ. NOTUM-mediated WNT silencing drives extravillous trophoblast cell lineage development. Proc Natl Acad Sci U S A. 2024 Oct; 121(40):e2403003121.
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Varberg KM, Dominguez EM, Koseva B, Varberg JM, McNally RP, Moreno-Irusta A, Wesley ER, Iqbal K, Cheung WA, Schwendinger-Schreck C, Smail C, Okae H, Arima T, Lydic M, Holoch K, Marsh C, Soares MJ, Grundberg E. Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape. Nat Commun. 2023 08 10; 14(1):4826.
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Thorpe J, Perry MD, Contreras O, Hurley E, Parker G, Harvey RP, Hill AP, Vandenberg JI. Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia. Stem Cell Res Ther. 2023 07 27; 14(1):183.
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McLennan R, Giniunaite R, Hildebrand K, Teddy JM, Kasemeier-Kulesa JC, Bolanos L, Baker RE, Maini PK, Kulesa PM. Colec12 and Trail signaling confine cranial neural crest cell trajectories and promote collective cell migration. Dev Dyn. 2023 05; 252(5):629-646.
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Shi L, Racedo SE, Diacou A, Park T, Zhou B, Morrow BE. Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation. Hum Mol Genet. 2022 04 22; 31(8):1197-1215.
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