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Daniel E. Forsha, MD, MHS

TitleDirector, Cardiovascular Imaging Research
InstitutionChildren's Mercy Kansas City
DepartmentHeart Center
Address2401 Gillham Rd
Kansas City MO 64108
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    Other Positions
    TitleAssiatant Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics

    TitleClinical Assistant Professor of Pediatrics
    InstitutionUniversity of Kansas School of Medicine
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    University of Colorado, Boulder, COBS2000Molecular, Cellular & Developmental Biology
    University of Colorado Health Sciences Center, Denver, COMD2007MD
    Duke University Medical Center, Durham, NC2010Pediatric Residency
    Duke University Medical Center, Durham, NCMasters2013Health Sciences in Clinical Research
    Duke University Medical Center, Durham, NC2014Pediatric Cardiology Fellowship

    Collapse Research 
    Collapse research overview
    Daniel Forsha, MD is an Associate Professor of Pediatrics in the Ward Family Heart Center at Children’s Mercy Kansas City. His broad research interests include the use of non-invasive imaging to measure patient outcomes in congenital heart disease with a special interest in measuring the beneficial impact of various types of exercise in this population. His research career began in a yeast bench research lab at the University of Colorado studying the interactions of a molecular chaperone protein before transitioning to clinical research during his pediatric residency and cardiology fellowship at Duke. Currently, Dr Forsha is the Director of Cardiovascular Imaging Research within the Heart Center and Co-Chairs the American Society of Echocardiography (ASE) Research Committee. His current and past research support is over one million dollars from the NIH, Additional Ventures Single Ventricle Research Fund, AHA, and a philanthropic donor. These funds support his research across multiple areas: 1) the impact of exercise and fitness on outcomes in the Down syndrome population, 2) the relationship between skeletal muscle health and Fontan fitness levels and cardiac function in the single ventricle population, 3) the effect of COVID on the heart as part of the Pediatric Heart Network MUSIC and CAMP studies, and 4) evaluating the negative effects of ventricular electro-mechanical dyssynchrony on cardiac function. This research has translated into over 40 peer reviewed publications and book chapters. He has regularly been invited to give educational and research lectures at conferences for the ASE, AHA, ACC, World Congress, and Euro-Echo. Dr. Forsha also mentor's young researchers in the field at Children’s Mercy, through his work at the ASE and the PRIISM initiative.

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gross RS, Thaweethai T, Rosenzweig EB, Chan J, Chibnik LB, Cicek MS, Elliott AJ, Flaherman VJ, Foulkes AS, Gage Witvliet M, Gallagher R, Gennaro ML, Jernigan TL, Karlson EW, Katz SD, Kinser PA, Kleinman LC, Lamendola-Essel MF, Milner JD, Mohandas S, Mudumbi PC, Newburger JW, Rhee KE, Salisbury AL, Snowden JN, Stein CR, Stockwell MS, Tantisira KG, Thomason ME, Truong DT, Warburton D, Wood JC, Ahmed S, Akerlundh A, Alshawabkeh AN, Anderson BR, Aschner JL, Atz AM, Aupperle RL, Baker FC, Balaraman V, Banerjee D, Barch DM, Baskin-Sommers A, Bhuiyan S, Bind MC, Bogie AL, Bradford T, Buchbinder NC, Bueler E, B?k?lmez H, Casey BJ, Chang L, Chrisant M, Clark DB, Clifton RG, Clouser KN, Cottrell L, Cowan K, D'Sa V, Dapretto M, Dasgupta S, Dehority W, Dionne A, Dummer KB, Elias MD, Esquenazi-Karonika S, Evans DN, Faustino EVS, Fiks AG, Forsha D, Foxe JJ, Friedman NP, Fry G, Gaur S, Gee DG, Gray KM, Handler S, Harahsheh AS, Hasbani K, Heath AC, Hebson C, Heitzeg MM, Hester CM, Hill S, Hobart-Porter L, Hong TKF, Horowitz CR, Hsia DS, Huentelman M, Hummel KD, Irby K, Jacobus J, Jacoby VL, Jone PN, Kaelber DC, Kasmarcak TJ, Kluko MJ, Kosut JS, Laird AR, Landeo-Gutierrez J, Lang SM, Larson CL, Lim PPC, Lisdahl KM, McCrindle BW, McCulloh RJ, McHugh K, Mendelsohn AL, Metz TD, Miller J, Mitchell EC, Morgan LM, M?ller-Oehring EM, Nahin ER, Neale MC, Ness-Cochinwala M, Nolan SM, Oliveira CR, Osakwe O, Oster ME, Payne RM, Portman MA, Raissy H, Randall IG, Rao S, Reeder HT, Rosas JM, Russell MW, Sabati AA, Sanil Y, Sato AI, Schechter MS, Selvarangan R, Sexson Tejtel SK, Shakti D, Sharma K, Squeglia LM, Srivastava S, Stevenson MD, Szmuszkovicz J, Talavera-Barber MM, Teufel RJ, Thacker D, Trachtenberg F, Udosen MM, Warner MR, Watson SE, Werzberger A, Weyer JC, Wood MJ, Yin HS, Zempsky WT, Zimmerman E, Dreyer BP. Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. PLoS One. 2024; 19(5):e0285635. PMID: 38713673.
      View in: PubMed
    2. Lopez L, Saurers DL, Barker PCA, Cohen MS, Colan SD, Dwyer J, Forsha D, Friedberg MK, Lai WW, Printz BF, Sachdeva R, Soni-Patel NR, Truong DT, Young LT, Altman CA. Guidelines for Performing a Comprehensive Pediatric Transthoracic Echocardiogram: Recommendations From the American Society of Echocardiography. J Am Soc Echocardiogr. 2024 Feb; 37(2):119-170. PMID: 38309834.
      View in: PubMed
    3. Madan N, Aly D, Kathol M, Buddhavarapu A, Rieth T, Sherman A, Forsha D. Relationship Between Obesity and Global Longitudinal Strain in the Pediatric Single Ventricle Fontan Population Across Ventricular Morphologies. J Am Heart Assoc. 2024 Feb 06; 13(3):e028616. PMID: 38240220.
      View in: PubMed
    4. Frank L, Helsel B, Dodd D, Bodde AE, Danon JC, Sherman JR, Forsha DE, Szabo-Reed A, Washburn RA, Donnelly JE, Ptomey LT. The association between cardiovascular health and cognition in adults with Down syndrome. J Neurodev Disord. 2023 12 06; 15(1):43. PMID: 38057709.
      View in: PubMed
    5. Forsha D, Eidem BW. The Pivotal Role of ASE in Promoting Early Career Clinician Scientists. J Am Soc Echocardiogr. 2023 Nov; 36(11):A13. PMID: 37925192.
      View in: PubMed
    6. McIntosh AM, Goyal A, Moser-Dungan C, Harvey B, Heching HJ, Aly DG, Madan N, Forsha D. Echocardiographic findings in non-hospitalised children and adolescents following acute COVID-19. Cardiol Young. 2024 Mar; 34(3):540-546. PMID: 37560822.
      View in: PubMed
    7. Krzywda K, Teson KM, Watson JS, Goudar S, Forsha D, Wagner JB, White DA. Peak Oxygen Consumption (V?O 2peak ) Recovery Delay in a Pediatric Fontan Population. Med Sci Sports Exerc. 2023 11 01; 55(11):1961-1967. PMID: 37418236.
      View in: PubMed
    8. Nagueh SF, Klein AL, Scherrer-Crosbie M, Fine NM, Kirkpatrick JN, Forsha DE, Nicoara A, Mackensen GB, Tilkemeier PL, Doukky R, Cheema B, Adusumalli S, Hill JC, Tanguturi VK, Ouyang D, Bdoyan SB, Strom JB. A Vision for the Future of Quality in Echocardiographic Reporting: The American Society of Echocardiography ImageGuideEcho Registry, Current and Future States. J Am Soc Echocardiogr. 2023 08; 36(8):805-811. PMID: 37256252.
      View in: PubMed
    9. Gross R, Thaweethai T, Rosenzweig EB, Chan J, Chibnik LB, Cicek MS, Elliott AJ, Flaherman VJ, Foulkes AS, Witvliet MG, Gallagher R, Gennaro ML, Jernigan TL, Karlson EW, Katz SD, Kinser PA, Kleinman LC, Lamendola-Essel MF, Milner JD, Mohandas S, Mudumbi PC, Newburger JW, Rhee KE, Salisbury AL, Snowden JN, Stein CR, Stockwell MS, Tantisira KG, Thomason ME, Truong DT, Warburton D, Wood JC, Ahmed S, Akerlundh A, Alshawabkeh AN, Anderson BR, Aschner JL, Atz AM, Aupperle RL, Baker FC, Balaraman V, Banerjee D, Barch DM, Baskin-Sommers A, Bhuiyan S, Bind MC, Bogie AL, Buchbinder NC, Bueler E, B?k?lmez H, Casey BJ, Chang L, Clark DB, Clifton RG, Clouser KN, Cottrell L, Cowan K, D'Sa V, Dapretto M, Dasgupta S, Dehority W, Dummer KB, Elias MD, Esquenazi-Karonika S, Evans DN, Faustino EVS, Fiks AG, Forsha D, Foxe JJ, Friedman NP, Fry G, Gaur S, Gee DG, Gray KM, Harahsheh AS, Heath AC, Heitzeg MM, Hester CM, Hill S, Hobart-Porter L, Hong TKF, Horowitz CR, Hsia DS, Huentelman M, Hummel KD, Iacono WG, Irby K, Jacobus J, Jacoby VL, Jone PN, Kaelber DC, Kasmarcak TJ, Kluko MJ, Kosut JS, Laird AR, Landeo-Gutierrez J, Lang SM, Larson CL, Lim PPC, Lisdahl KM, McCrindle BW, McCulloh RJ, Mendelsohn AL, Metz TD, Morgan LM, M?ller-Oehring EM, Nahin ER, Neale MC, Ness-Cochinwala M, Nolan SM, Oliveira CR, Oster ME, Payne RM, Raissy H, Randall IG, Rao S, Reeder HT, Rosas JM, Russell MW, Sabati AA, Sanil Y, Sato AI, Schechter MS, Selvarangan R, Shakti D, Sharma K, Squeglia LM, Stevenson MD, Szmuszkovicz J, Talavera-Barber MM, Teufel RJ, Thacker D, Udosen MM, Warner MR, Watson SE, Werzberger A, Weyer JC, Wood MJ, Yin HS, Zempsky WT, Zimmerman E, Dreyer BP. Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. medRxiv. 2023 May 12. PMID: 37214806.
      View in: PubMed
    10. Buddhavarapu A, Chauhan D, Erickson LA, Elliott MD, Warren M, Forsha DE. The Evolution of Longitudinal Strain Across Various Univentricular Morphologies Prior to Superior Cavopulmonary Anastomosis. J Am Soc Echocardiogr. 2023 10; 36(10):1100-1109. PMID: 37141928.
      View in: PubMed
    11. Carey PM, Yeh HW, Krzywda K, Teson KM, Watson JS, Goudar S, Forsha D, White DA. Moderators of peak respiratory exchange ratio during exercise testing in children and adolescents with Fontan physiology. Cardiol Young. 2023 Nov; 33(11):2334-2341. PMID: 36776115.
      View in: PubMed
    12. Elias MD, Truong DT, Oster ME, Trachtenberg FL, Mu X, Jone PN, Mitchell EC, Dummer KB, Sexson Tejtel SK, Osakwe O, Thacker D, Su JA, Bradford TT, Burns KM, Campbell MJ, Connors TJ, D'Addese L, Forsha D, Frosch OH, Giglia TM, Goodell LR, Handler SS, Hasbani K, Hebson C, Krishnan A, Lang SM, McCrindle BW, McHugh KE, Morgan LM, Payne RM, Sabati A, Sagiv E, Sanil Y, Serrano F, Newburger JW, Dionne A. Examination of Adverse Reactions After COVID-19 Vaccination Among Patients With a History of Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2023 01 03; 6(1):e2248987. PMID: 36595296.
      View in: PubMed
    13. Haligheri G, Johnson T, Kathol M, Kuzava L, Goth N, Staggs VS, Donnelly JE, Ptomey LT, Forsha D. Early cardiac dysfunction in obese adolescents with Down syndrome or autism. Cardiol Young. 2023 Sep; 33(9):1678-1685. PMID: 36184834.
      View in: PubMed
    14. Azar FM, Beck VDY, Matthews AM, Forsha DE, Hilgenkamp TIM. Cardiac Structure and Function in Adults with Down Syndrome. Int J Environ Res Public Health. 2022 09 28; 19(19). PMID: 36231610.
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    15. Goudar S, Forsha D, White DA, Sherman A, Shirali G. Single ventricular strain measures correlate with peak oxygen consumption in children and adolescents with Fontan circulation. Cardiol Young. 2023 Jul; 33(7):1136-1142. PMID: 35864813.
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    16. Heching HJ, Goyal A, Harvey B, Malloy-Walton L, Follansbee C, Mcintosh A, Forsha D. Electrocardiographic changes in non-hospitalised children with COVID-19. Cardiol Young. 2022 Dec; 32(12):1910-1916. PMID: 34986922.
      View in: PubMed
    17. Kohli U, Desai L, Chowdhury D, Harahsheh AS, Yonts AB, Ansong A, Sabati A, Nguyen HH, Hussain T, Khan D, Parra DA, Su JA, Patel JK, Ronai C, Bohun M, Freij BJ, O'Connor MJ, Rosanno JW, Gupta A, Salavitabar A, Dorfman AL, Hansen J, Frosch O, Profita EL, Maskatia S, Thacker D, Shrivastava S, Harris TH, Feingold B, Berger S, Campbell M, Idriss SF, Das S, Renno MS, Knecht K, Asaki SY, Patel S, Ashwath R, Shih R, Phillips J, Das B, Ramachandran P, Sagiv E, Bhat AH, Johnson JN, Taggart NW, Imundo J, Nakra N, Behere S, Patel A, Aggarwal A, Aljemmali S, Lang S, Batlivala SP, Forsha DE, Conners GP, Shaw J, Smith FC, Pauliks L, Vettukattil J, Shaffer K, Cheang S, Voleti S, Shenoy R, Komarlu R, Ryan SJ, Snyder C, Bansal N, Sharma M, Robinson JA, Arnold SR, Salvatore CM, Kumar M, Fremed MA, Glickstein JS, Perrotta M, Orr W, Rozema T, Thirumoorthi M, Mullett CJ, Ang JY. mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis?in?Adolescents: A Survey Study. J Pediatr. 2022 04; 243:208-213.e3. PMID: 34952008.
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    18. Truong DT, Dionne A, Muniz JC, McHugh KE, Portman MA, Lambert LM, Thacker D, Elias MD, Li JS, Toro-Salazar OH, Anderson BR, Atz AM, Bohun CM, Campbell MJ, Chrisant M, D'Addese L, Dummer KB, Forsha D, Frank LH, Frosch OH, Gelehrter SK, Giglia TM, Hebson C, Jain SS, Johnston P, Krishnan A, Lombardi KC, McCrindle BW, Mitchell EC, Miyata K, Mizzi T, Parker RM, Patel JK, Ronai C, Sabati AA, Schauer J, Sexson Tejtel SK, Shea JR, Shekerdemian LS, Srivastava S, Votava-Smith JK, White S, Newburger JW. Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults: Suspected Myocarditis After COVID-19 Vaccination. Circulation. 2022 02; 145(5):345-356. PMID: 34865500.
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    19. Truong DT, Trachtenberg FL, Pearson GD, Dionne A, Elias MD, Friedman K, Hayes KH, Mahony L, McCrindle BW, Oster ME, Pemberton V, Powell AJ, Russell MW, Shekerdemian LS, Son MB, Taylor M, Newburger JW. The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives. Am Heart J. 2022 01; 243:43-53. PMID: 34418362.
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    20. Aly D, Ramlogan S, France R, Schmidt S, Hinzman J, Sherman A, Goudar SP, Forsha D. Intervendor Agreement for Right Ventricular Global Longitudinal Strain in Children. J Am Soc Echocardiogr. 2021 07; 34(7):786-793. PMID: 33561494.
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    21. Ptomey LT, Szabo-Reed AN, Martin LE, Mayo MS, Washburn RA, Gorczyca AM, Lepping RJ, Lee P, Forsha DE, Sherman JR, Danon JC, Donnelly JE. The promotion of physical activity for the prevention of Alzheimer's disease in adults with Down Syndrome: Rationale and design for a 12?Month randomized trial. Contemp Clin Trials Commun. 2020 Sep; 19:100607. PMID: 32642594.
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    22. Ramlogan S, Aly D, France R, Schmidt S, Hinzman J, Sherman A, Goudar SP, Forsha D. Reproducibility and Intervendor Agreement of Left Ventricular Global Systolic Strain in Children Using a Layer-Specific Analysis. J Am Soc Echocardiogr. 2020 01; 33(1):110-119. PMID: 31668503.
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    23. Forsha D, Li L, Joseph N, Kutty S, Friedberg MK. Association of left ventricular size with regional right ventricular mechanics in Hypoplastic Left Heart Syndrome. Int J Cardiol. 2020 01 01; 298:66-71. PMID: 31402159.
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    24. Doshi AR, Opfer EK, Forsha D. Anomalous aortic origin of the right coronary artery from the non-coronary sinus of Valsalva. Cardiol Young. 2019 Apr; 29(4):531-533. PMID: 30957729.
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    25. Ptomey LT, Szabo AN, Willis EA, Greene JL, Danon JC, Washburn RA, Forsha DE, Donnelly JE. Remote Exercise for Adults with Down Syndrome. Transl J Am Coll Sports Med. 2018 Apr 15; 3(8):60-65. PMID: 29930988.
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    26. Forsha D, Risum N, Barker P. Activation delay-induced mechanical dyssynchrony in single-ventricle heart disease. Cardiol Young. 2017 Sep; 27(7):1390-1391. PMID: 28597808.
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    27. Forsha D, Risum N, Smith PB, Kanter RJ, Samad Z, Barker P, Kisslo J. Frequent Activation Delay-Induced Mechanical Dyssynchrony and Dysfunction in the Systemic Right Ventricle. J Am Soc Echocardiogr. 2016 11; 29(11):1074-1083. PMID: 27624591.
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    28. Forsha D, Slorach C, Chen CK, Sherman A, Mertens L, Barker P, Kisslo J, Friedberg MK. Patterns of Mechanical Inefficiency in Pediatric Dilated Cardiomyopathy and Their Relation to Left Ventricular Function and Clinical Outcomes. J Am Soc Echocardiogr. 2016 Mar; 29(3):226-36. PMID: 26711366.
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    29. Malowitz JR, Forsha DE, Smith PB, Cotten CM, Barker PC, Tatum GH. Right ventricular echocardiographic indices predict poor outcomes in infants with persistent pulmonary hypertension of the newborn. Eur Heart J Cardiovasc Imaging. 2015 Nov; 16(11):1224-31. PMID: 25851325.
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    30. Thattaliyath BD, Forsha DE, Stewart C, Barker PC, Campbell MJ. Evaluation of Right Ventricular Myocardial Mechanics Using Velocity Vector Imaging of Cardiac MRI Cine Images in Transposition of the Great Arteries Following Atrial and Arterial Switch Operations. Congenit Heart Dis. 2015 Jul-Aug; 10(4):371-9. PMID: 25655213.
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    31. Forsha D, Risum N, Rajagopal S, Dolgner S, Hornik C, Barnhart H, Kisslo J, Barker P. The influence of angle of insonation and target depth on speckle-tracking strain. J Am Soc Echocardiogr. 2015 May; 28(5):580-6. PMID: 25655402.
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    32. Forsha D, Slorach C, Chen CK, Stephenson EA, Risum N, Hornik C, Wagner G, Mertens L, Barker P, Kisslo J, Friedberg MK. Classic-pattern dyssynchrony and electrical activation delays in pediatric dilated cardiomyopathy. J Am Soc Echocardiogr. 2014 Sep; 27(9):956-64. PMID: 25063467.
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    33. Rajagopal S, Forsha DE, Risum N, Hornik CP, Poms AD, Fortin TA, Tapson VF, Velazquez EJ, Kisslo J, Samad Z. Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views. J Am Soc Echocardiogr. 2014 Jun; 27(6):657-665.e3. PMID: 24656881.
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    34. Forsha D, Risum N, Kropf PA, Rajagopal S, Smith PB, Kanter RJ, Samad Z, Sogaard P, Barker P, Kisslo J. Right ventricular mechanics using a novel comprehensive three-view echocardiographic strain analysis in a normal population. J Am Soc Echocardiogr. 2014 Apr; 27(4):413-22. PMID: 24508364.
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    35. Hill KD, Lodge AJ, Forsha D, Fleming GA, Green AS, Rhodes JF. A strategy for atrial septal defect closure in small children that eliminates long-term wall erosion risk. Catheter Cardiovasc Interv. 2013 Mar; 81(4):654-9. PMID: 22639441.
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    36. Forsha D, Rhodes JF, Williams DA, Lodge AJ, Li JS. A rare coronary collateral in pulmonary atresia and intact septum with coronary sinusoids. World J Pediatr Congenit Heart Surg. 2012 Apr 01; 3(2):255-9. PMID: 23804785.
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    37. Forsha D, Li JS, Smith PB, van der Ploeg AT, Kishnani P, Pasquali SK. Cardiovascular abnormalities in late-onset Pompe disease and response to enzyme replacement therapy. Genet Med. 2011 Jul; 13(7):625-31. PMID: 21543987.
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    38. Church C, Goehring B, Forsha D, Wazny P, Poyton RO. A role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant. J Biol Chem. 2005 Jan 21; 280(3):1854-63. PMID: 15507444.
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    39. Forsha D, Church C, Wazny P, Poyton RO. Structure and function of Pet100p, a molecular chaperone required for the assembly of cytochrome c oxidase in Saccharomyces cerevisiae. Biochem Soc Trans. 2001 Aug; 29(Pt 4):436-41. PMID: 11498004.
      View in: PubMed
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