 Antimetabolites, Antineoplastic
"Antimetabolites, Antineoplastic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antimetabolites that are useful in cancer chemotherapy.
| Descriptor ID |
D000964
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| MeSH Number(s) |
D27.505.519.186.144 D27.505.954.248.144 D27.888.569.042.030
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Antimetabolites, Antineoplastic".
Below are MeSH descriptors whose meaning is more specific than "Antimetabolites, Antineoplastic".
This graph shows the total number of publications written about "Antimetabolites, Antineoplastic" by people in this website by year, and whether "Antimetabolites, Antineoplastic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2009 | 0 | 3 | 3 | | 2011 | 2 | 1 | 3 | | 2012 | 2 | 2 | 4 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 3 | 0 | 3 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 2 | 3 | 5 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Antimetabolites, Antineoplastic" by people in Profiles.
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Taylor ZL, Miller TP, Board SG, Poweleit EA, Chavana A, Weisnicht A, Brown AL, Bernhardt MB, Schafer ES, O'Brien MM, Castellino SM, Ramsey LB. What Is the Expected Clearance of Methotrexate? A Therapeutic Drug Monitoring Reference Guide for High-Dose Methotrexate Use in Pediatric Malignancies. Pediatr Blood Cancer. 2025 Jul; 72(7):e31744.
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Heldrup J, Bleyer A, Ramsey L, Schaff L, Bernhardt B, Schwartz S, Chatelut E, Hwang M, Ten C, Guscott M, Howard S. New recommendations for reversal of high-dose methotrexate cytotoxicity with folinic acid. Cancer Chemother Pharmacol. 2025 Mar 13; 95(1):41.
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Guest EM, Kairalla JA, Devidas M, Hibbitts E, Carroll AJ, Heerema NA, Kubaney HR, August MA, Ramesh S, Yoo B, Farooqi MS, Pauly MG, Wechsler DS, Miles RR, Reid JM, Kihei CD, Gore L, Raetz EA, Hunger SP, Loh ML, Brown PA. Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children's Oncology Group trial AALL15P1. Haematologica. 2024 Dec 01; 109(12):3918-3927.
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Christensen SR, Jensen CF, Heldrup J, Taylor Z, Ramsey LB, Rosth?j S. Hypoalbuminemia in children with acute lymphoblastic leukemia: relation to asparaginase therapy and impact on high dose methotrexate elimination. Cancer Chemother Pharmacol. 2024 Dec; 94(6):775-785.
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Tentoni N, Hwang M, Villanueva G, Combs R, Lowe J, Ramsey LB, Taylor ZL, Carrillo TM, Aumente MD, L?pez-Vi?au L?pez T, Rizzari C, Howard SC. Early therapeutic drug monitoring of methotrexate and its association with acute kidney injury: A retrospective cohort study. Cancer Med. 2024 Sep; 13(17):e70176.
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Chavana AN, Taylor ZL, DeGroote N, Lindsay HB, Sauer HE, Mason EJ, Schafer ES, Miller TP, Castellino SM, Pommert L, O'Brien MM, Ramsey LB, Bernhardt MB, Brown AL. Toxicity profile of high-dose methotrexate in young children with central nervous system tumors. Pediatr Blood Cancer. 2024 Oct; 71(10):e31213.
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Turner AJ, Haidar CE, Yang W, Boone EC, Offer SM, Empey PE, Haddad A, Tahir S, Scharer G, Broeckel U, Gaedigk A. Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clin Transl Sci. 2024 01; 17(1):e13699.
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Taylor ZL, Miller TP, Poweleit EA, DeGroote NP, Pommert L, Awoniyi O, Board SG, Ugboh N, Joshi V, Ambrosino N, Chavana A, Bernhardt MB, Schafer ES, O'Brien MM, Castellino SM, Ramsey LB. Clinical covariates that improve the description of high dose methotrexate pharmacokinetics in a diverse population to inform MTXPK.org. Clin Transl Sci. 2023 11; 16(11):2130-2143.
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Higgerson K, Flatt T. Skin Toxicity Due to Mercaptopurine in Maintenance Therapy Among Children With Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2023 05 01; 45(4):e514-e517.
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Ibarra M, Combs R, Taylor ZL, Ramsey LB, Mikkelsen T, Buddington RK, Heldrup J, Barreto JN, Guscott M, Lowe J, Hurmiz C, Marada S, Howard SC, Schaiquevich P. Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing. Br J Clin Pharmacol. 2023 02; 89(2):660-671.
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