 Terrie G. Flatt, DO, MA
| Title | Physician and Director, Spanish Language Clinic |
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| Institution | Children's Mercy Kansas City |
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| Department | Pediatrics |
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| Address | 2401 Gillham Rd
Kansas City MO 64108
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| Title | Associate Professor of Pediatrics |
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| Institution | University of Missouri-Kansas City |
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| Department | Pediatrics |
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| Title | Clinical Assistant Professor of Pediatrics |
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| Institution | University of Kansas Medical Center |
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| Department | Pediatrics |
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 Biography | University of North Texas Health Science Center, Fort Worth, Texas | DO | | | | Driscoll Children's Hospital, Corpus Christi, TX | Residency | | Pediatrics | | Children's Mercy Hospital, Kansas City, MO | Fellowship | | Pediatric Hematology/Oncology |
| 2012 - 2013 | Kaleidoscope Award , Chidren's Mercy Hospital | | 2013 | Golden Apple Mentor Award, Children's Mercy Hosptial | | 2018 | Golden Apple Mentor Award, Children's Mercy Hosptial | | 2019 - 2020 | Shining Star Patient Care Award, Children's Mercy Hosptial | | 2020 | Shining Star Patient Care Award, Children's Mercy Hosptial | | 2019 - 2020 | Best Division Teaching Award, Children's Mercy Hosptial |
Overview Research My research interest focus on pediatric cancer outcomes among Hispanic children. The goal of our team is to better understand the biologic and socio-cultural factors that affect cancer outcomes among Hispanic children. We have 3 international current studies that include over 8 hospitals in Mexico. Our primary focus is acute lymphoblastic leukemia and childhood sarcomas. My primary research team includes Dr. Lilia Garcia Rodriguez, MD who oversees all studies in Mexico and Dr. Elizabeth Gonzalez Dominguez, MD/PhD Candidate who is performing bench research at CMH for our sarcoma study. I am committed to global health and educating physicians and PhDs from Mexico and Latin America.
(Terrie Flatt, DO)Jan 1, 2013 - Dec 31, 2014 AMC Cares Cancer Grant
Developing a Bilingual Clinical Model of Care
Role Description: Program grant to develop bilingual clinic model at CMH |
| (Terrie Flatt, DO)Oct 1, 2013 - Sep 30, 2015 Hyundai Hope on Wheels Scholar Grant
Development of Bilingual Clinic Model
Role: PI |
| (Terrie Flatt, DO)Oct 1, 2015 - Sep 30, 2015 Hyundai Hope on Wheels Impact Grant
Development of language navigator program for Spanish speakers with limited English proficiency
Role Description: This purpose of this funding was to establish a dedicated bilingual language navigator to the HOPE Clinic at CMH.
Role: PI |
| (Terrie Flatt, DO)Oct 1, 2015 - Oct 1, 2020 Midwest Cancer Alliance Grant for Study
The Role of Ethnicity in Pediatric ALL
Role Description: The goal of this study is to better understand how ancestral markers pre-dispose Hispanic patients to Pre-B ALL.
Role: PI |
| (Terrie Flatt, DO)Jun 1, 2017 - Aug 18, 2020 Midwest Cancer Alliance Grant
Variations in the TPMT and NUDT15 Genes among Mexican Children
Role Description: The goal of this study is better understand why Hispanic children experience profound toxicities with the administration of 6-Mercaptopurine, a key drug used to cure ALL.
Role: PI |
Bibliography
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Vacek M, Z?rraga Vargas LC, Gonz?lez Dom?nguez E, Garcia Rodriguez L, Tello Teran OA, Mojica Cardoso C, Ocampo Roosens LV, Acevedo Fernandez JJ, Li W, Lee B, Olalla Tapia JS, Flatt T. Increased Incidence of TdT-negative Pre-B Acute Lymphoblastic Leukemia Associated With Poor Prognostic Features Among Mexican Children in Central Mexico. J Pediatr Hematol Oncol. 2024 03 01; 46(2):e131-e136. PMID: 38132672.
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Gonzalez E, Flatt TG, Farooqi M, Johnson L, Ahmed AA. Polypyrimidine Tract Binding Protein: A Universal Player in Cancer Development. Curr Mol Med. 2023 Oct 24. PMID: 37877563.
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Gonzalez E, Ahmed AA, McCarthy L, Chastain K, Habeebu S, Zapata-Tarres M, Cardenas-Cardos R, Velasco-Hidalgo L, Corcuera-Delgado C, Rodriguez-Jurado R, Garc?a-Rodr?guez L, Parrales A, Iwakuma T, Farooqi MS, Lee B, Weir SJ, Flatt TG. Perinucleolar Compartment (PNC) Prevalence as an Independent Prognostic Factor in Pediatric Ewing Sarcoma: A Multi-Institutional Study. Cancers (Basel). 2023 Apr 10; 15(8). PMID: 37190159.
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Higgerson K, Flatt T. Skin Toxicity Due to Mercaptopurine in Maintenance Therapy Among Children With Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2023 05 01; 45(4):e514-e517. PMID: 37027323.
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McElroy S, Myers GD, Flatt T. A Pediatric Case of Treatment-related Myelodysplastic Syndrome While on Therapy for Pre-B Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2023 05 01; 45(4):e518-e521. PMID: 36706304.
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Mc Dermott S, Dargan C, Gonzalez Dominguez E, Music Aplenc L, Flatt T, Iqbal N. Therapeutic plasma exchange for multiorgan dysfunction among critically ill pediatric patients with leukemia: A single-institutional experience. J Clin Apher. 2022 Aug; 37(4):367-375. PMID: 35405029.
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Ahmed AA, Farooqi MS, Habeebu SS, Gonzalez E, Flatt TG, Wilson AL, Barr FG. NanoString Digital Molecular Profiling of Protein and microRNA in Rhabdomyosarcoma. Cancers (Basel). 2022 Jan 21; 14(3). PMID: 35158790.
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Ahmed AA, Habeebu S, Farooqi MS, Gamis AS, Gonzalez E, Flatt T, Sherman A, Surrey L, Arnold MA, Conces M, Koo S, Dioufa N, Barr FG, Tsokos MG. MYOD1 as a prognostic indicator in rhabdomyosarcoma. Pediatr Blood Cancer. 2021 09; 68(9):e29085. PMID: 33913590.
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Hall EM, Yin DE, Goyal RK, Ahmed AA, Mitchell GS, St Peter SD, Flatt TG, Ahmed IA, Li W, Hendrickson RJ, August KJ, Myers GD. Tisagenlecleucel infusion in patients with relapsed/refractory ALL and concurrent serious infection. J Immunother Cancer. 2021 01; 9(1). PMID: 33472856.
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Stoner A, Miller JO, Flatt T, Wallisch JS. Extracorporeal Membrane Oxygenation as a Bridge to Chimeric Antigen Receptor T-cell Therapy for Severe Refractory Sepsis in the Setting of Relapsed Refractory Pediatric Acute Lymphoblastic Leukemia: A Case Report. Crit Care Explor. 2020 Apr; 2(4):e0093. PMID: 32426735.
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McCarthy LC, Chastain K, Flatt TG, Taboada E, Garola R, Herriges J, Cooley LD, Ahmed AA. Neuroblastoma in Adolescents and Children Older than 10 Years: Unusual Clinicopathologic and Biologic Features. J Pediatr Hematol Oncol. 2019 11; 41(8):586-595. PMID: 30973487.
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Garcia Rodriguez L, Cole, T Flatt, T . Pediatric Blood and Cancer. Pre-B ALL among Hispanic Children at a Single Institution. 2019; 66.
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Garcia Rodriguez, L MD, Jefferson M; Radhi, M; Sherman, A; Chignola, B; Flatt, T. The Role of Hispanic Ethnicity on Outcomes in Pediatric Hematopoietic Stem Cell Transplantation at a Single Institution. 2017; 64.
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Garcia Rodriguez, L. Juárez Villegas L; Flatt, T. Pediatric Blood and Cancer. Hodgkin Lymphoma: Characteristics and Overall Survival at a Single Institution in Mexico. 2017; 64.
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Reddavallia, N.; Li, W; Sherman, A; Santa-Olalla Tapia, J; Flatt, T. Pediatric Blood and Cancer. Ki-67 Proliferative Index as a Prognostic Marker for Therapeutic Response among Pediatric Patients with De-Novo Acute Lymphoblastic Leukemia. 2017; 64.
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Flatt, T; Donnelly, S; Torres, T. Pediatric Blood and Cancer. Improving Patient Care for Hispanic Pediatric Oncology Patients with Limited English Proficiency. 2017; 64(S3).
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Flatt, T; Ramphal, A. Pediatric Blood and Cancer. Utilizing Focus Groups to Improve Health Care Among Children with Hematologic and Oncologic Diseases. 2015; 62(s4).
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Lopez-Guardeño, N, Tello, O, Raya, S., Santa-Olalla Tapia, J, Zwick, D, Flatt, T. Pediatric Blood and Cancer. A Comparison of Acute Lymphoblastic Leukemia in the US and Mexico at Two Single Institutions. 2015; 62.
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Flatt, T., Hayes, A, Woods, G. . Building a new model of clinical care: Hospitalist coverage on the Hematology/Oncology in-patient service. 2012.
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Flatt T, Neville K, Lewing K, Dalal J. Successful treatment of fanconi anemia and T-cell acute lymphoblastic leukemia. Case Rep Hematol. 2012; 2012:396395. PMID: 22937327.
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Elliott, A, Flatt, T, Shore, R. Pediatric Blood & Cancer. Isolated de novo CNS AML in a 3-year-old Child: Case Report. 2011; 56.
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Flatt, T, Dalal, J. . Characteristics and Outcome of Pediatric Stem Cell Transplant Patients with Invasive Fungal Infection. 2010.
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Flatt T, Lewing K, Gonzalez C, Anthony K, Ryan R, Jones R, Gamis A, Dalal J. Successful mobilization with AMD3100 and filgrastim with engraftment of autologous peripheral blood stem cells in a heavily pretreated pediatric patient with recurrent Burkitt lymphoma. Pediatr Hematol Oncol. 2010 Mar; 27(2):138-49. PMID: 20201695.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2010 | 2 | | 2011 | 1 | | 2012 | 2 | | 2015 | 2 | | 2017 | 4 | | 2019 | 2 | | 2020 | 1 | | 2021 | 2 | | 2022 | 2 | | 2023 | 5 |
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a) “Not Everyone is the Same: Understanding Pediatric ALL among Hispanics” Invited lecturer at Hospital del Niño Morelense, Cuernavaca, Mexico, June 2014b) “Point-Counterpoint: Patients' vs. Clinicians' Definitions of Engagement—One Size Does Not Fit All” (invited speaker ASPHO, Minneapolis, MN, May 2016.Not Everyone is the Same: Understanding Pediatric ALL among Hispanics” Keynote Speaker, Hospital del Nino, DIF, Congreso International de Calidad;, Pachuca, Hidalgo Mexico, June 2016c) Pediatric Lymphoma, (invited speaker) Society of Pediatric Oncology in Latin America (SLAOP), Lima Peru, May 2016Not Everyone is the Same: Understanding Acute Lymphoblastic Leukemia among Hispanic Children.” Keynote speaker. First International Pediatric Oncology Conference, Hospital del Nino Mexicano, Federico Gomez, Mexico City, Mexico, May 21, 2017EL Futuro del Niño con Cancer”. First International Pediatric Cancer Conference. Cuernavaca, Morelos, Mexico, Keynote Speaker, Feb 9, 2018Not Everyone is the Same: The Role of Hispanic Ancestry and Acute Lymphoblastic Leukemia”; Grand Rounds, Children’s Mercy Hospital, Kansas City, MO August 9, 2018My Child is Sick and You Do Not Speak My Language” Minority Health Care Symposium, Invited Speaker; University of North Texas Health Science Center, Fort Worth, Texas September 18-19, 2018Population Health: Why it Matters?” Grand Rounds, University of North Texas Health Science Center, September 19, 2018El Futuro de Oncología” Terapias Dirigidas”, Keynote Speaker, 36th National Congress, Mexican Society of Oncology Guadalajara, Mexico, November 7, 2018El Papel de la Etnicidad en la Leucemia Linfoblástica Aguda” Invited Speaker. 36th National Congress, Mexican Society of Oncology Guadalajara, Mexico, November 8, 2018Adenopatia ¿Que Pensar y Hacer? Invited Speaker; XXX Congreso Latinoamericano De Oncología Pediátrica, SLAOP Guayaquil Ecuador, April 3, 2019Las Actualizaciones del Linfoma Burkitt’s” Invited Speaker; XXX Congreso Latinoamericano De Oncología Pediátrica, SLAOP Guayaquil Ecuador, April 4, 2019El Papel del PET-CT en los Linfomas no Hodgkin” Invited Speaker; XXX Congreso Latinoamericano De Oncología Pediátrica, SLAOP Guayaquil Ecuador, April 4, 2019m) “¿Cómo se Trata el Sarcoma Sinovial Hoy en Día?” Invited Speaker; XXX Congreso Latinoamericano De Oncología Pediátrica, SLAOP Guayaquil Ecuador, April 5, 2019Como Diagnosticar la Leucemia?” Invited Speaker XXV Congreso Internacional de Hematología y Oncología Pediatría Mexicana, Acapulco, Mexico June 21, 2019o) “¿La Etnicidad Influye el Pronóstico?” (Does Ethnicity Influence Outcomes?) Keynote Speaker; XXV Congreso Internacional de Hematología y Oncología Pediatría Mexicana, Acapulco, Mexico June 20, 2019La Realidad del Hispano en los EUA (The Reality of the Hispanic Patient in the US);” Invited Speaker XXV Congreso Internacional de Hematología y Oncología Pediatría Mexicana, Acapulco, Mexico June 21, 2019
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